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Ji, Hong,Wang, Jianfa,Liu, Juxiong,Guo, Jingru,Wang, Zhongwei,Zhang, Xu,Guo, Li,Yang, Huanmin Asian Australasian Association of Animal Productio 2013 Animal Bioscience Vol.26 No.3
Zi geese (Anser anser domestica) belong to the white geese and are excellent layers with a superior feed-to-egg conversion ratio. Quantitative gene expression analysis, such as Real-time qRT-PCR, will provide a good understanding of ovarian function during egg-laying and consequently improve egg production. However, we still don't know what reference genes in geese, which show stable expression, should be used for such quantitative analysis. In order to reveal such reference genes, the stability of seven genes were tested in five tissues of Zi geese. Methodology/Principal Findings: The relative transcription levels of genes encoding hypoxanthine guanine phosphoribosyl transferase 1 (HPRT1), ${\beta}$-actin (ACTB), ${\beta}$-tubulin (TUB), glyceraldehyde-3-phosphate-dehydrogenase (GADPH), succinate dehydrogenase flavoprotein (SDH), 28S rRNA (28S) and 18S rRNA (18S) have been quantified in heart, liver, kidney, muscle and ovary in Zi geese respectively at different developmental stages (1 d, 2, 4, 6 and 8 months). The expression stability of these genes was analyzed using geNorm, NormFinder and BestKeeper software. Conclusions: The expression of 28S in heart, GAPDH in liver and ovary, ACTB in kidney and HPRT1 in muscle are the most stable genes as identified by the three different analysis methods. Thus, these genes are recommended for use as candidate reference genes to compare mRNA transcription in various developmental stages of geese.
( Ji Hong ),( Peng Zhang ),( I Na Yoon ),( Jae Sam Hwang ),( Jin Ku Kang ),( Ho Kim ) 한국미생물 · 생명공학회 2017 Journal of microbiology and biotechnology Vol.27 No.4
Clostridium difficile, which causes pseudomembranous colitis, releases toxin A and toxin B. These toxins are considered to be the main causative agents for the disease pathogenesis, and their expression is associated with a marked increase of apoptosis in mucosal epithelial cells. Colonic epithelial cells are believed to form a physical barrier between the lumen and the submucosa, and abnormally increased mucosal epithelial cell apoptosis is considered to be an initial step in gut inflammation responses. Therefore, one approach to treating pseudomembranous colitis would be to develop agents that block the mucosal epithelial cell apoptosis caused by toxin A, thus restoring barrier function and curing inflammatory responses in the gut. We recently isolated an antimicrobial peptide, Periplanetasin-2 (Peri-2, YPCKLNLKLGKVPFH) from the American cockroach, whose extracts have shown great potential for clinical use. Here, we assessed whether Peri-2 could inhibit the cell toxicity and inflammation caused by C. difficile toxin A. Indeed, in human colonocyte HT29 cells, Peri-2 inhibited the toxin A-induced decrease in cell proliferation and ameliorated the cell apoptosis induced by this toxin. Moreover, in the toxin A-induced mouse enteritis model, Peri-2 blocked the mucosal disruption and inflammatory response caused by toxin A. These results suggest that the American cockroach peptide Peri-2 could be a possible drug candidate for addressing the pseudomembranous colitis caused by C. difficile toxin A.
Visual lock-on to invisible target for unmanned aerial vehicle
Jihong Min,Jungho Kim,Yekeun Jung,In So Kweon IET 2012 Electronics letters Vol.48 No.14
<P>Presented is a robust visual lock-on framework for an unmanned aerial vehicle (UAV) that utilises geometric relations between the UAV pose and the 3D local map defined by the positions of the target and natural landmarks. Experimental results using real datasets demonstrate the robustness of the proposed method compared to state-of-the-art visual tracking methods.</P>
Jihong Lee,남윤미 한국은행 2019 經濟分析 Vol.25 No.4
This paper studies localization effects of knowledge spillovers in Korea using U.S. patents granted over the period 1996-2015. The “sample-matching” analysis initiated by Jaffe, Trajtenberg, and Henderson (1993) is adopted. We do not find evidence of positive localization effects in Korea. In particular, controlling for the existing geographic distribution of knowledge production, the frequency of domestic citations of Korean patents is no more than the citation frequency from overseas, and the difference is decreasing within the sample period. We also examine localization effects across regions and industries, and compare Korea with Taiwan and Japan. 본 연구는 1996-2015년 기간 동안 개인이 아닌 기업이나 기관이 미국 특허청(USPTO)에 출원 및 등록한 특허자료를 사용하여 우리나라 지식전파의 지역화 효과를 분석하였다. 이를 위해 Jaffe, Trajtenberg, and Henderson (1993)이 제시한 ‘샘플-매칭(matched-sample)’ 분석틀을 활용하였으며, 지식 생산의 지리적 집적 분포를 통제한 후 국내에 있는 발명가의 특허를 국내 다른 발명가가 인용할 확률과 해외에 있는 발명가가 인용할 확률을 비교하는 방식으로 지식전파의 지역화 효과를 추정하였다. 분석결과, 우리나라 지식전파의 지역화 효과의 증거를 발견할 수 없었으며 오히려 감소하고 있는 추세를 보이고 있는 것으로 나타났다. 이는 지식 창출의 지리적 집적 정도를 통제한 후에는 국내 발명가의 특허를 타 기관이나 기업 소속의 국내 다른 발명가가 인용할 확률과 해외에 있는 발명가가 인용할 확률이 같거나 오히려 후자가 높은 것을 의미한다. 아울러 본 연구는 국내 지역별 및 산업별 지식전파의 지역화 효과와 함께, 한국의 지역화 효과를 대만과 일본의 경우와 비교분석 하였다.
Cholesterol Granuloma in the Mandible ; A Case Report
Jihong Kim,Seong Doo Hong,Jae lL Lee,Sam Pyo Hong 대한구강악안면병리학회 2007 대한구강악안면병리학회지 Vol.31 No.2
Cholesterol granuloma(CG) occurs frequently in association with chronic middle ear diseases. pa rti cul arly dis eases in the mastoid antrum a nd ai r cells of the tempora l bone. and much less frequent ly in paranasal sinuses, It occurs f1'eq uentJy seconda1'Y to massive hemor1'hage of oral and pal'aol'aJ cysts, Howeve1'. It has nevel' been I'eported to OCCUI' solely wi thout any association of pl'eexisting lesion in the mandibJe We expel'ienced development of unusuaJ cholestel'ol granuloma in the mandible, Seventy year old female pl'e sented diffuse ha1'd swelling on the left mandibular a rea with Iymphadenopathy in the left cer vical Iymph node Radi og1'aphic exarnination showed a well circumsc ribed multi locular radiolucency resembling soap bubble appeara nce with tooth di s placement and root resorption‘ leading to the radiogrphic imp1'ession of dentigerous cyst 0 1' 。dontogenic cys t or amelobJas toma, CT showed bucco-lingua lly undul ating expansi le lesion with co rticated ma l'gin from the left posterior mandibular bocly to the anterior ramus. including #46, #47 ancl #43. and the mass containing in the lesion showed s lightly lower a ttenuation than muscJe leading to the impression of ameloblastoma, The mass aftel' surgical excis ion composed of 3 sac like structures, measuring 4,1 cm, 1, 3cm ancl 1.4cm in diame ter respectively, One sac was t ightl y a ttached to the #46. l'eRembling dentigerous cyst, Mi croscopic examination showed a large numbel' of c h이 es te rol clefts in association with hemol'rhage, hemosiderin pigments and fO l'eign body giant cells, There was no evidence of cyst 0 1' other lesions, CG should be taken into diffe l'enti a l diagnosis in addition to odontogenic cysts and tumors when radiographica lly well ci rcumscribed multilocuJal' radiolucent lesion occurs
A Model of Infinitely Repeated Litigation with Correlated Decisions
Jihong Lee 한국계량경제학회 2010 계량경제학보 Vol.21 No.4
This paper considers a model of repeated litigation in which a single long-lived defendant faces an infinite sequence of short-lived plaintiffs. Court decisions are correlated across periods, rejecting the presence of precedent effects. We derive unique Markov perfect equilibrium payoffs for the long-lived defendant, and compare them to the predictions of a corresponding two-period benchmark model.