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Post-fire Study on Mechanical Properties of Damaged Ultra-high Strength Concrete
Xiao Lyu,Guang-Hao Jia,Gan-Ping Shu,Xin Zhang,Er-Feng Du,Wen-Ming Wang 한국강구조학회 2022 International Journal of Steel Structures Vol.22 No.6
In order to study the eff ect of steel tube, pre-load and temperature on residual performance of heated ultra-high strength concrete (UHSC), an experimental program was carried out to investigate the physical and mechanical properties of UHSC post-fi re in room temperature. With total of 54 standard cylindrical concrete specimens subjected to various temperatures ranging from 62 °C to 496 °C, their residual compressive strength, elastic modulus, peak strain was measured after natural cooling down. By comparing the test results of standard cylindrical concrete specimens with the results of the bare specimens in and after fi re, it is known that the residual compressive strength of standard cylindrical concrete specimens decayed more serious after exposing to same temperature. Seen from the results, the temperature which the specimens suff ered was found to be responsibility to the reduction of the compressive strength, elastic modulus, peak strain. As the temperature up to 300 °C, the strength reduction coeffi cient of UHSC was 0.67 ~ 0.68 and the elastic modulus reduction coeffi cient of UHSC was 0.41 ~ 0.51 with peak strain coeffi cient ε cr ( T ) /ε 0 1.57 ~ 1.67. Finally, based on the analysis of test results, simple formulae were proposed to describe the eff ect of temperature on residual performance of heated UHSC which infi lled the steel tube.
Liu, Jia,Ge, Yang-Yang,Zhu, Hong-Cheng,Yang, Xi,Cai, Jing,Zhang, Chi,Lu, Jing,Zhan, Liang-Liang,Qin, Qin,Yang, Yan,Yang, Yue-Hua,Zhang, Hao,Chen, Xiao-Chen,Liu, Zhe-Ming,Ma, Jian-Xin,Cheng, Hong-Yan,S Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.16
Radiation therapy is an important treatment for head and neck squamous cell carcinoma (HNSCC). However, how to promote radiation sensitivity in HNSCC remains a challenge. This study aimed to investigate the radiosensitizing effects of fenofibrate on HNSCC and explore the underlying mechanisms. HNSCC cell lines CNE-2 and KB were subjected to ionizing radiation (IR), in the presence or absence of fenofibrate treatment. Cell growth and survival, apoptosis and cell cycle were evaluated. In addition, CNE-2 cells were xenografted into nude mice and subjected to IR and/or fenofibrate treatment. The expression of cyclinB and CDK1 was detected by Western blotting. Our results showed that fenofibrate efficiently radiosensitized HNSCC cells and xenografts in mice, and induced apoptosis and G2/M arrest via reducing the activity of the CDK1/cyclinB1 kinase complex. These data suggest that fenofibrate could be a promising radiosensitizer for HNSCC radiotherapy.
Ma Gao,Xu Xiao-Quan,Zhu Liu-Ning,Jiang Jia-Suo,Su Guo-Yi,Hu Hao,Bu Shou-Shan,Wu Fei-Yun 대한영상의학회 2021 Korean Journal of Radiology Vol.22 No.2
Objective: To compare and correlate the findings of intravoxel incoherent motion (IVIM) magnetic resonance (MR) imaging and arterial spin labeling (ASL) imaging in characterizing parotid gland tumors. Materials and Methods: We retrospectively reviewed 56 patients with parotid gland tumors evaluated by MR imaging. The true diffusion coefficient (D), pseudo-diffusion coefficient (D*), and fraction of perfusion (f) values of IVIM imaging and tumor-to-parotid gland signal intensity ratio (SIR) on ASL imaging were calculated. Spearman rank correlation coefficient, chi-squared, Mann-Whitney U, and Kruskal-Wallis tests with the post-hoc Dunn-Bonferroni method and receiver operating characteristic curve assessments were used for statistical analysis. Results: Malignant parotid gland tumors showed significantly lower D than benign tumors (p = 0.019). Within subgroup analyses, pleomorphic adenomas (PAs) showed significantly higher D than malignant tumors (MTs) and Warthin’s tumors (WTs) (p < 0.001). The D* of WTs was significantly higher than that of PAs (p = 0.031). The f and SIR on ASL imaging of WTs were significantly higher than those of MTs and PAs (p < 0.05). Significantly positive correlation was found between SIR on ASL imaging and f (r = 0.446, p = 0.001). In comparison with f, SIR on ASL imaging showed a higher area under curve (0.853 vs. 0.891) in discriminating MTs from WTs, although the difference was not significant (p = 0.720). Conclusion: IVIM and ASL imaging could help differentiate parotid gland tumors. SIR on ASL imaging showed a significantly positive correlation with f. ASL imaging might hold potential to improve the ability to discriminate MTs from WTs.
Optimal Structure Design of Multi-functional Folding Drawing Board based on TRIZ Theory
Jiang Jin-gang,Xu Xiao-lei,Wang Zhao,Liu Yun-feng,Cui Shi-jia,Sun Jing-hao 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.2
In drawing area, aiming at the problems of drawing breadth and angle cannot be adjusted individually and not convenient to carry, a kind of multi-functional folding drawing board is designed by us. The appearance of the multi-functional folding drawing board is kind of drawing board, some light materials like basswood and rigid plastics are used in main structure of the drawing board to make it light and convenient to carry. The main structure can be folded and it is suitable for A1 and A2 drawings. In the designing procedure, dip angle adjusted mechanism by worm wheel and gear, magnetic pull-in mechanism, leading rail, slide-way, drawer, tool library, paper bag and horn locks are applied based on modularity designing theory. Finite element analysis of key components of drawing board is analyzed.
Seismic behavior of cross-shaped concrete-filled steel tubular columns
Ji-Cheng Zhang,Xiao-Yu Liu,Lei Zeng,Guo-Feng Du,Jia-Hao Xiao 국제구조공학회 2021 Steel and Composite Structures, An International J Vol.40 No.3
This paper experimentally investigated the behavior of a cross-shaped concrete-filled steel tubular (C-CFST) column subjected to a constant axial load and a low-cycle repeated loading. Nine C-CFST columns with different length-width ratio, width-thickness ratio and axial compression ratio were designed, and the failure mode, hysteresis curve, skeleton curve, ductility, stiffness degradation and energy dissipation capacity of each specimen were studied and analyzed. The results indicated that the cross-shaped steel tube had a strong restraining effect on the core concrete, and C-CFST columns of different sectional dimensions all exhibited favorable seismic behavior, which is suitable for middle-high residential buildings. An increase of length-width ratio enhanced the initial stiffness with a decrease of ductility, and more rapid stiffness degradation during loading. Specimens with smaller width-thickness ratios had higher ductility, stiffness, and energy dissipation capacity. A larger axial compression ratio could reduce the bearing capacity, and cause the stiffness to degrade faster. Moreover, a hysteretic model of C-CFST columns was also proposed based on an analysis of the test results.
A Novel Distributed Equivalent Circuit Model for Single-Core Cables
Li Rui-Fang,Hu Hao,Cao Xiao-Bin,Li Zhong-Mei,Li Jun-Hao,Zhu Chuan-Lin,Liu Le-Jia 대한전기학회 2024 Journal of Electrical Engineering & Technology Vol.19 No.1
The number of cables used for urban power supply increases rapidly. The sheath current in these cables, which is generated via induction, produces a current loss. When the situation is serious, the ground lead and the middle connector of the cable will be burned. In this paper, the existing single-core cable equivalent circuit model is used to calculate the sheath current of a 3-phase cable under the condition of non-transposition and cross connection. By comparing the calculated results with the simulation and the experimental results, it is found that the current distribution law for the sheath, which was obtained using the existing model, difers substantially from both the simulation and actual measurements. The error reason of the existing model is revealed, and it is found that the magnitude and phase of the current in the metal sheath of the cable varies with the position under the combined efect of distributed capacitances in the cable and the core-current fux, especially for a 3-phase cross connection, each section of the cable does not meet Kirchhof’s laws, but the sheath electric current in the existing models are considered equal everywhere. Therefore, a novel cable equivalent model is proposed in this paper, which is based on a distributed circuit, and an equation to calculate the sheath current is derived. The model presented in this paper corrects the problems of the existing model, which can be applied to power system, subway, high-speed rail, and any application of single-core cables.
Insect-specific microRNA involved in the development of the silkworm Bombyx mori
Yong Zhang,Xue Zhou,Xie Ge,Jiang-Hao Jiang,Mu-Wang Li,Shi-Hai Jia,Xiao-Nan Yang,Yun-Chao Kan,Xue-Xia Miao,Guo-Ping Zhao,Fei Li,Yong-Ping Huang 한국응용곤충학회 2009 한국응용곤충학회 학술대회논문집 Vol.2009 No.10
MicroRNAs (miRNAs) are endogenous non-coding genes that participate in post-transcription regulation by either degrading mRNA or blocking its translation. It is considered to be very important in regulating insect development and metamorphosis. Insects are the largest group of animals and are extremely valuable in biological and agriculture research. Insects are also important pests to human health and agriculture, and efforts are necessary protect both humans and plants from disease and damage. Despite their importance, insects lag behind mammals, nematodes, and plants in miRNA research. At present, only 279 insect miRNAs have been identified from Drosophila melanogaster, Anopheles gambiae, Apis mellifera, Bombyx mori, and D. pseudoobscura in miRBase, and most of these miRNAs were computationally predicted without experimental validation. Functional analysis of insect miRNAs has only been conducted in D. melanogaster.
Staged Improvement in Awareness of Disease for Elderly Cancer Patients in Southern China
Li, Xing,Dong, Min,Wen, Jing-Yun,Wei, Li,Ma, Xiao-Kun,Xing, Yan-Fang,Deng, Yun,Chen, Zhan-Hong,Chen, Jie,Ruan, Dan-Yun,Lin, Ze-Xiao,Wang, Tian-Tian,Wu, Dong-Hao,Liu, Xu,Hu, Hai-Tao,Lin, Jia-Yu,Li, Zhu Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.15
Background: In mainland China, awareness of disease of elderly cancer patients largely relies on the patients' families. We developed a staged procedure to improve their awareness of disease. Materials and Methods: Participants were 224 elderly cancer patients from 9 leading hospitals across Southern China. A questionnaire was given to the oncologists in charge of each patient to evaluate the interaction between family and patients, patient awareness of their disease and participation in medical decision-making. After first cycles of treatment, increased information of disease was given to patients with cooperation of the family. Then patient awareness of their disease and participation in medical decision-making was documented. Results: Among the 224 cancer elderly patients, 26 (11.6%) made decisions by themselves and 125 (55.8%) delegated their rights of decision-making to their family. Subordinate family members tended to play a passive role in decision-making significantly. Patients participating more in medical decision-making tended to know more about their disease. However, in contrast to the awareness of disease, patient awareness of violation of medical recommendations was reversely associated with their participation in medical decision-making. Improvement in awareness of diagnosis, stages and prognosis was achieved in about 20% elderly cancer patients. About 5% participated more actively in medical decision-making. Conclusions: Chinese elderly cancer patient awareness of disease and participation in medical decision-making is limited and relies on their family status. The staged procedure we developed to improve patient awareness of disease proved effective.