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BFRP 보강이 직사각형 단면 철근콘크리트 기둥의 지진거동에 미치는 영향
이혜린 ( Hyerin Lee ),조정현 ( Junghyun Cho ),이승건 ( Seung-geon Lee ),이수형 ( Su-hyung Lee ),홍기증 ( Kee-jeung Hong ) 한국구조물진단유지관리공학회 2020 한국구조물진단유지관리공학회 논문집 Vol.24 No.6
지진동 하의 구조 시스템에서 기둥은 가장 중요한 구조 요소 중 하나이다. 이러한 관계로, 철근콘크리트(RC) 기둥의 내진 성능에 FRP 보강이 미치는 영행을 평가하기 위하여 광범위한 실험 연구가 이루어졌다. 이 중 상당수는 CFRP 또는 GFRP로 보강된 원형 단면 또는 정사각형 단면의 RC 기둥의 지진 거동에 집중하였다. 단면의 형태가 FRP 보강으로 인한 구속 효과에 영향을 미치기 때문에, 보강 효과와 최종 파괴 패턴이 형상에 따라 상이할 수 있다. 본 연구에서는 현무암 섬유를 함유한 BFRP 시트와 복합섬유 패널로 보강한 직사각형 단면을 가진 RC기둥의 지진 거동을 살펴보기 위하여 반복하중 실험을 수행하였다. 실험 결과는 보강 효과가 크지 않았음을 보여주는데, BFRP 시트와 복합섬유 패널에 의한 구속 효과의 증가가 미미했음을 의미하며, 이는 기둥 단면 형상에 일부 기인하는 것으로 판단된다. Columns are one of the most critical parts of a structural system subjected to earthquake excitations. In this regard, extensive experimental studies have been conducted to evaluate the effect of fiber reinforced polymer (FRP) wrapping on the seismic performance of reinforced concrete (RC) columns. Among them, many studies focused on the behavior of circular or square RC columns strengthened with CFRP or GFRP sheets. Since the cross-sectional shape affects confinement by FRP wrapping, its strengthening effect and final damage pattern may differ with shapes. In this study, a series of cyclic tests was conducted to investigate the seismic behavior of rectangular reinforced concrete columns strengthened with basalt-based fiber reinforced polymer (BFRP) sheets and composite fiber panels. The result shows that the effect of strengthening is not significant, and it implies a little increase of confinement by BFRP sheets and composite fiber panels, which is considered partly due to the cross-sectional shape of the columns.
Flavisolibacter tropicus sp. nov., isolated from tropical soil
Lee, Jae-Jin,Kang, Myung-Suk,Kim, Gyung Soon,Lee, Chang Soek,Lim, Sangyong,Lee, Jidam,Roh, Si Hyeon,Kang, Hyerin,Ha, Jung Min,Bae, Sojung,Jung, Hee-Young,Kim, Myung Kyum Microbiology Society 2016 International journal of systematic and evolutiona Vol.66 No.-
Two-Photon Microscopy of the Mouse Peripheral Cornea Ex Vivo
Lee, Jun Ho,Kim, Ki Hean,Lee, Seunghun,Jeong, Hyerin,Kim, Myoung Joon Wolters Kluwer Health, Inc. All rights reserved. 2016 Cornea Vol.35 No.suppl1
PURPOSE:: To investigate the 3-dimensional (3D) cell and extracellular matrix (ECM) structure of mouse peripheral corneas in normal and corneal neovascularization tissues using 2-photon microscopy (TPM) based on both intrinsic and extrinsic moxifloxacin contrasts. METHODS:: Peripheral corneas in freshly enucleated mouse eyes were imaged by TPM based on both intrinsic and extrinsic contrasts. Intrinsic autofluorescence and second harmonic generation were used to image cells and ECM collagen, respectively. Moxifloxacin ophthalmic solution was applied to image cells. The peripheral cornea, limbus, and sclera were imaged in 3D. In addition to normal mice, mouse models of suture-induced corneal neovascularization were imaged to visualize changes in the microstructure. RESULTS:: Complex 3D cell and ECM structures in the cornea, limbus, and sclera were visualized by TPM. TPM images based on intrinsic contrasts visualized both cell and ECM structures, and TPM images based on moxifloxacin visualized cell structures with enhanced contrast. On the limbus side of the mouse peripheral cornea, TPM images visualized the vasculature in the limbus, the trabecular meshwork/Schlemm canal, iris, and ciliary body. On the scleral side, TPM images visualized cell and ECM structures in the sclera and multiple cell layers below the sclera. TPM images of the peripheral cornea in the corneal neovascularization condition visualized the extension of vasculature from the limbus to the cornea. CONCLUSIONS:: TPM imaging based on both intrinsic and external moxifloxacin contrasts visualized detailed 3D cell and ECM microstructures in the mouse peripheral cornea. TPM based on moxifloxacin might be advantageous for studying cell structures by enhancing image contrast.
A Three-Year Longitudinal Study of Risk Factors for Suicidality in North Korean Defectors
Lee Hyerin,An Ji Hyun,Chang Hyein,Jun Jin Yong,Hong Jin Pyo 대한의학회 2023 Journal of Korean medical science Vol.38 No.28
Background: This longitudinal study examined risk factors for future suicidality among North Korean defectors (NKDs) living in South Korea. Methods: The subjects were 300 NKDs registered with a regional adaptation center (the Hana Center) in South Korea. Face-to-face interviews were conducted using the North Korean version of the World Health Organization’s Composite International Diagnostic Interview to diagnose mental disorders according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Subjects were also asked about sociodemographic and clinical factors at baseline. At follow-up after three years, the NKDs (n = 172 respondents) were asked to participate in an online survey, responding to self-questionnaires about suicidality. Logistic regression analyses were used to explore associations between baseline variables and future suicidality among NKDs. Results: Thirty (17.4%) of the 172 survey respondents reported suicidality at follow-up. The presence of health problems over the past year, any prior suicidality at baseline, a higher score on a trauma-related scale, and a lower score on a resilience scale at baseline were associated with greater odds of suicidality at follow-up after adjusting for age, sex, and educational level. Of all mental disorder categories, major depressive disorder, dysthymia, agoraphobia, and social phobia were also associated with significantly increased odds of suicidality at follow-up after adjusting for age, sex, educational level, and prior suicidality at baseline. Conclusion: Resilience, a previous history of suicidality, and the presence of lifetime depressive disorder and anxiety disorder should be given consideration in mental health support and suicide prevention in NKDs.
Lee, Hyehyeon,Jeong, Hyerin,Lee, Sun Young,Kim, Soo Shin,Jang, Kyung Lib Korean Society for Molecular and Cellular Biology 2019 Molecules and cells Vol.42 No.1
Methylation of HBV cccDNA has been detected in vivo and in vitro; however, the mechanism and its effects on HBV replication remain unclear. HBx derived from a 1.2-mer HBV replicon upregulated protein levels and enzyme activities of DNA methyltransferase 1 (DNMT1), 3a, and 3b, resulting in methylation of the negative regulatory region (NRE) in cccDNA, while none of these effects were observed with an HBx-null mutant. The HBx-positive HBV cccDNA expressed higher levels of HBc and produced about 4-fold higher levels of HBV particles than those from the HBx-null counterpart. For these effects, HBx interrupted the action of NRE binding protein via methylation of the C-1619 within NRE, resulting in activation of the core promoter. Treatment with 5-Aza-2′dC or DNMT1 knock-down drastically impaired the ability of HBx to activate the core promoter and stimulate HBV replication in 1.2-mer HBV replicon and in vitro infection systems, indicating the positive role of HBx-mediated cccDNA methylation in HBV replication.