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      • Verification of Recovery Effect on Motor Function of Plegic Upper Limb after Stroke by UR-System 2

        Hitomi Hattori,Ryosuke Takeichi,Norihiro Toya,Yoshifumi Morita,Hirofumi Tanabe,Yoshiaki Takagi,Norio Hasegawa 제어로봇시스템학회 2016 제어로봇시스템학회 국제학술대회 논문집 Vol.2016 No.10

        We have developed a new rehabilitation support system, UR-System 2, for restoring the motor function of a plegic upper limb after a stroke. Its design is based on knowledge gained during clinical testing of the UR-System. The UR-System 2 was equipped with the facilitating function of elbow extension based on the proprioceptive neuromuscular facilitation technique and the measurement function for evaluating isolated movements. In this study, we verified the effectiveness of the facilitating function on a patient. In addition, we verified the immediate recovery effect of training with the UR-System 2 on a patient. In this training, elbow flexion and extension of the paralyzed forearm were repeated 150 times. As a result, we confirmed the improvement of isolated movements, namely the decrease in pronation torque of the paralyzed forearm during training and the suppression of the pronation angle before and after training. Moreover, the active ranges of motion and the modified Ashworth scale score improved after training, which indicated a reduction in spastic paralysis. These results show the immediate recovery effect of training with the UR-System 2 for restoring the motor function of the upper limb.

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        Anatomical study of the bone morphology of the anterior talofibular ligament attachment

        Hitomi Fujishiro,Akimoto Nimura,Mizuki Azumaya,Soichi Hattori,Osamu Hoshi,Keiichi Akita 대한해부학회 2023 Anatomy & Cell Biology Vol.56 No.3

        Anterior talofibular ligament (ATFL) injuries are the most common cause of ankle sprains. To ensure anatomicallyaccurate surgery and ultrasound imaging of the ATFL, anatomical knowledge of the bony landmarks around the ATFL attachment to the distal fibula is required. The purpose of the present study was to anatomically investigate the ATFL attachment to the fibula with respect to bone morphology and attachment structures. First, we analyzed 36 feet using micro-computed tomography. After excluding 9 feet for deformities, the remaining 27 feet were used for chemically debrided bone analysis and macroscopic and histological observations. Ten feet of living specimens were observed using ultrasonography. We found that a bony ridge was present at the boundary between the attachments of the ATFL and calcaneofibular ligament (CFL) to the fibula. These two attachments could be distinguished based on a difference in fiber orientation. Histologically, the ATFL was attached to the anterodistal part of the fibula via fibrocartilage anterior to the bony ridge indicating the border with the CFL attachment. Using ultrasonography in living specimens, the bony ridge and hyperechoic fibrillar pattern of the ATFL could be visualized. We established that the bony ridge corresponded to the posterior margin of the ATFL attachment itself. The ridge was obvious, and the superior fibers of the ATFL have directly attached anteriorly to it. This bony ridge could become a valuable and easy-to-use landmark for ultrasound imaging of the ATFL attachment if combined with the identification of the fibrillar pattern of the ATFL.

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        Running exercise and food restriction affect bone chemical properties in young female rats

        Yuki Aikawa,Yuich Noma,Umon Agata,Yuya Kakutani,Satoshi Hattori,Hitomi Ogata,Ken Kiyono,Naomi Omi 한국운동영양학회 2023 Physical Activity and Nutrition (Phys Act Nutr) Vol.27 No.2

        [Purpose] To investigate the effects of a combination of running and food restriction on the chemical properties of the bone in young female rats using Raman spectroscopy. Furthermore, we investigated whether the chemical property parameters correlated with the bone-breaking strength. [Methods] Female Sprague–Dawley rats (7 weeks old) were randomly divided into four groups: sedentary and ad libitum feeding (SED, n = 8), voluntary running exercise and ad libitum feeding (EX, n = 8), sedentary and 30% food-restricted (SED-FR, n = 8), and voluntary running exercise and 30% food-restricted (EX- FR, n = 8). The experiment was conducted for a period of 12 weeks. Four parameters measured by Raman spectroscopy were used to evaluate the bone chemical quality. [Results] Exercise and restriction had significant interactions on the mineral to matrix ratio. The mineral-to-matrix ratio in the SED-FR group was significantly higher than that in the SED group and significantly lower in the EX-FR group than that in the SED-FR group. Running exercise had significant effects on increasing the crystallinity and carbonate-to-phosphate ratio. In the ad libitum intake condition, there were significant positive correlations between breaking energy and crystallinity (r = 0.593) and between breaking energy and carbonate-to-phosphate ratio (r = 0.854). [Conclusion] Our findings show that running exercise and food restriction, alone or in combination, affect the chemical properties of bone. Furthermore, under ad libitum intake conditions, positive correlations were found between the breaking energy and crystallinity, or carbonate-to-phosphate ratio.

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