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      • Exploring Prospects for Cross-Border Development in Southwest China's Border Regions

        Fan Gang(Gang Fan) 아시아사회과학학회 2023 Jornal of Asia Social Science Vol.10 No.2

        This paper explores the opportunities for along-border opening-up in Southwest China's border areas, analyzes the advantages and challenges of this region in opening up, and proposes measures and suggestions for further tapping its potential for opening up. The geographical advantage, economic advantage, and policy advantage of this region in opening up are discussed, as well as the challenges of geographical disadvantage, economic difficulties, and cultural differences. To further tap the potential of along-border opening-up in Southwest China's border areas, the paper suggests strengthening infrastructure construction, promoting industrial upgrading, and enhancing cultural exchange. The research findings offer insights into the development prospects and trends of along-border opening-up in this region.

      • Problems and Challenges Facing the Promotion of Common Prosperity in China's Southwest Border Ethnic Minority Areas

        Fan Gang(Gang Fan) 아시아사회과학학회 2022 Jornal of Asia Social Science Vol.9 No.2

        China's Southwest border areas are home to many ethnic minority groups and have long struggled with poverty and underdevelopment. The promotion of common prosperity in these areas is a critical task for China's overall poverty alleviation strategy. However, there are significant challenges facing the promotion of common prosperity in these regions. Inadequate infrastructure is one of the major challenges facing the promotion of common prosperity in China's Southwest border areas. The region's transportation, electricity, and communication infrastructure are often underdeveloped, which can hinder the region's economic development and make it difficult for residents to access basic services. To address this challenge, the Chinese government has launched a number of infrastructure construction projects, such as the construction of highways and railways, to improve connectivity and promote economic development in the region. Low levels of education and vocational skills are also a significant challenge facing the promotion of common prosperity in China's Southwest border areas. Many residents in these regions lack access to quality education and vocational training opportunities, which can limit their economic opportunities and hinder the region's overall development. To address this challenge, the Chinese government has launched a number of education and vocational training programs to improve the skills and employability of residents in these areas. Limited economic opportunities are also a significant challenge facing the promotion of common prosperity in China's Southwest border areas. The region's economy is often dominated by traditional industries, such as agriculture and mining, which can limit the region's economic growth potential. To address this challenge, the Chinese government has launched a number of measures to promote the development of new and emerging industries, such as high-tech industries and cultural tourism. The promotion of common prosperity in China's Southwest border areas is a critical task for China's overall poverty alleviation strategy. However, there are significant challenges facing the promotion of common prosperity in these regions, including inadequate infrastructure, low levels of education and vocational skills, and limited economic opportunities. To address these challenges, the Chinese government has launched a number of measures and programs to improve infrastructure, education, and economic opportunities in these regions. By addressing these challenges, China can promote the common prosperity of ethnic minority areas and achieve its poverty alleviation goals.

      • Visualization Analysis of Eco-tourism Resources Development Research in China Based on Citespace

        Fan Gang,Liu Chaoyang 아시아사회과학학회 2021 Jornal of Asia Social Science Vol.5 No.3

        This paper analyzes the hot spots and cutting-edge topics in the research field of ecotourism resources development in China in recent 10 years, so as to facilitate relevant researchers to understand the research status in this field. Taking the academic papers related to the development and research of ecotourism resources in China from 2010 to 2019 in the Web of Science database as the research object, the co-occurrence of authors, countries, institutions and subject words was analyzed by using the bibliometric visualization software CiteSpace. A total of 13,820 research papers on the development of China s ecotourism resources were published in the search scope, and the number of published papers showed an increasing trend year by year, which attracted wide attention from many disciplines and fields. In recent years, Chinese researchers have carried out extensive and in-depth research on the development of ecotourism resources from various disciplines and fields.

      • IL-35 Over-expression is Associated with Genesis of Gastric Cancer

        Fan, Yong-Gang,Zhai, Jing-Ming,Wang, Wei,Feng, Bing,Yao, Guo-Liang,An, Yan-Hui,Zeng, Chao Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.7

        Overexpression of interleukin (IL)-35 has been found in a variety of malignancies, but the expression status in gastric cancer has yet to be elucidated clearly. In the present study, positive expression of EBI3 and p35 was 63.3% and 70.0% of cases, respectively. EBI3 expression was strongly related with larger tumor size and invasion depth (P<0.05). Similarly, expression of p35 was also correlated with larger tumor size (P<0.05). These results indicate that IL-35 might be involved in growth of gastric cancer. Interestingly, EBI3 and p35 expressions were positive correlated with Ki-67 expression. Moreover, EBI3 immunoreactivity was associated with Bcl-2 staining. Our data suggest IL-35 is correlated with genesis of gastric cancer by regulating growth and apoptosis.

      • KCI등재

        Volatile Compounds of Orange Wines Produced with and without Peel Contact

        Gang Fan,Xiaolin Yao,Yongxia Xu,Huanhuan Li,Hongfei Fu,Kexing Wang,Siyi Pan 한국식품과학회 2009 Food Science and Biotechnology Vol.18 No.6

        The present study focused on the effects of peel contact on the volatile compounds of orange wines. The volatile compounds were analyzed by sensory and instrumental analyses. Solid-phase microextraction (SPME) was used for extraction of volatile compounds. A total of 19 and 27 volatile compounds were identified in without and with peel contact wines respectively. Esters were quantitatively the dominant group of volatile compounds in without peel contact wines, while terpenes were the most abundant compounds in peel contact wines. Totally 11 and 14 new formed compounds were found in without and with peel contact wines, mainly were esters, alcohols, and acids. According to sensory analysis, the peel contact wine showed a more citrus-like and fruity aroma than the wines without peel contact.

      • Comparative Effectiveness of Risk-adapted Surveillance vs Retroperitoneal Lymph Node Dissection in Clinical Stage I Nonseminomatous Germ Cell Testicular Cancer: A Retrospective Follow-up Study of 81 Patients

        Fan, Gang,Zhang, Lin,Yi, Lu,Jiang, Zhi-Qiang,Ke, Yang,Wang, Xiao-Shan,Xiong, Ying-Ying,Han, Wei-Qin,Zhou, Xiao,Liu, Chun,Yu, Xie Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.8

        Purpose: To retrospective assess the potential predictors for relapse and create an effective clinical mode for surveillance after orchidectomy in clinical stage I non-seminomatous germ cell testicular tumors (CSI-NSGCTs). Materials and Methods: We analyzed data for CSI-NSGCTs patients with non-lymphatic vascular invasion, %ECa < 50% (percentage of embryonal carcinoma < 50%), and negative or declining tumor markers to their half-life following orchidectomy (defined as low-risk patients); these patients were recruited from four Chinese centers between January 1999 and October 2013. Patients were divided into active surveillance group and retroperitoneal lymph node dissection (RPLND) group according to different therapeutic methods after radical orchidectomy was performed. The disease-free survival rates (DFSR) and overall survival rates (OSR) of the two groups were compared by Kaplan-Meier analysis. Results: A total of 121 patients with CSI-NSGCT were collected from four centers, and 81 low-risk patients, including 54 with active surveillance and 27 with RPLND, were enrolled at last. The median follow-up duration was 66.2 (range 6-164) months in the RPLND group and 65.9 (range 8-179) months in the surveillance group. OSR was 100% in active surveillance and RPLND groups, and DFSR was 89.8% and 87.0%, respectively. No significant difference was observed between these two groups ($X_2=0.108$, P=0.743). No significant difference was observed between the patients with a low percentage of embryonal carcinoma (<50%) and those without embryonal carcinoma (87.0% and 91.9%, $X_2=0.154$, P=0.645). No treatment-related complications were observed in the active surveillance group whereas minor and major complications were observed in 13.0% and 26.1% of the RPLND group, respectively. Conclusions: Active surveillance resulted in similar DFSR and OSR compared with RPLND in our trial. Patients with low-risk CSI-NSGCTs could benefit from risk-adapted surveillance after these patients were subjected to radical orchidectomy.

      • Present Situation and Countermeasures of Ecotourism Resources Development in Tibet

        Fan Gang,Tang Yumin 아시아사회과학학회 2022 Jornal of Asia Social Science Vol.6 No.2

        With the improvement of people s leisure time and the strengthening of the country s development of the western region, the construction of the western region is speeding up, and people s yearning for the mysterious western region is becoming increasingly prominent. Tibet s unique natural ecology and social and historical process have created its unique tourism resources. Plateau, mountains, snow-capped mountains, glaciers, forests, grasslands, lakes, hot springs, geothermal water, etc. constitute a unique natural landscape. Spectacular temples and ancient buildings, strong religious atmosphere and charming eco-tourism resources in Tibet constitute a unique natural wonder, which has great development potential in developing eco-tourism in Tibet. According to the superior conditions of Tibet s eco-tourism resources, this paper starts with the characteristics of Tibet s eco-tourism resources and the development of Tibet s tourism industry, and concludes that there are some problems in the current development of Tibet s eco-tourism resources, such as backward propaganda and development, single types of tourism products, poor infrastructure conditions, lack of effective management, and weak awareness of environmental protection , and analyzes and summarizes the relevant countermeasures for developing Tibet s eco-tourism resources.

      • KCI등재

        Enhancing Cellulase Production in Thermophilic Fungus Myceliophthora thermophila ATCC42464 by RNA Interference of cre1 Gene Expression

        ( Fan Yang ),( Yanfen Gong ),( Gang Liu ),( Shengming Zhao ),( Juan Wang ) 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.7

        The role of CRE1 in a thermophilic fungus, Myceliophthora thermophila ATCC42464, was studied using RNA interference. In the cre1-silenced strain C88, the filter paper hydrolyzing activity and β-1,4-endoglucanase activity were 3.76-, and 1.31-fold higher, respectively, than those in the parental strain when the strains were cultured in inducing medium for 6 days. The activities of β-1,4-exoglucanase and cellobiase were 2.64-, and 5.59-fold higher, respectively, than those in the parental strain when the strains were cultured for 5 days. Quantitative reverse-transcription polymerase chain reaction showed that the gene expression of egl3, cbh1, and cbh2 was significantly increased in transformant C88 compared with the wild-type strain. Therefore, our findings suggest the feasibility of improving cellulase production by modifying the regulator expression, and an attractive approach to increasing the total cellulase productivity in thermophilic fungi.

      • KCI등재

        Recovery of Native Protein from Potato Root Water by Expanded Bed Adsorption with Amberlite XAD7HP

        Fan-Kui Zeng,Hong Liu,Peng-Jun Ma,Gang Liu 한국생물공학회 2013 Biotechnology and Bioprocess Engineering Vol.18 No.5

        Potato root water (PRW) contains ~1.5%protein. In this study, expanded bed adsorption (EBA)chromatography with Amberlite XAD7HP resin adsorbent was used to isolate native protein from crude PRW. The optimal pH and ionic strength for potato protein binding onto Amberlite XAD7HP were 5.0 and 20 mmol/L. The EBA-refined proteins were dried by vacuum freeze drying and spray drying at varying outlet temperatures. Results indicated that low temperature spray drying was the most cost effective method with respect to retaining protease inhibitor activities. The dried protein concentrates appeared bright yellow or dark reddish brown, with a total glycoalkaloid content of ~170 μg/g. The protease inhibitor activity was ~400 mg/g and 11 ~ 12 mg/g for trypsin inhibition and chymotrypsin inhibition, respectively. The results presented here suggest that EBA using Amberlite XAD7HP as the adsorbent is a feasible strategy for the direct adsorption of native protein from crude PRW.

      • SCIESCOPUSKCI등재

        Study of Hair Melanins in Various Hair Color Alpaca (Lama Pacos)

        Fan, Ruiwen,Yang, Gang,Dong, Changsheng Asian Australasian Association of Animal Productio 2010 Animal Bioscience Vol.23 No.4

        The aim of this study was to measure the hair melanins of various colors and to find the relationship between the quantity of melanins and hair color phenotypes in alpacas. According to the Munsell color system, 3 healthy alpacas were selected for each of the 22 different hair color phenotypes (66 alpacas altogether). Alpaca hair was taken from the lateral thoracic region and then dissolved with different solutions to obtain melanins. The values of alkali-soluble melanins (ASM), eumelanin (EM) and pheomelanin (PM) were measured by spectrophotometric assay, and labeled as Sp.ASM, Sp.EM and Sp.PM, respectively. Data were analyzed using SPSS11.5 software. Results showed that average Sp.ASM and Sp.PM were increased as the color deepened from white to black, ranging from 0.500 to 4.543 for Sp.ASM and from 0.268 to 1.457 for Sp.EM. However, average Sp.PM had no such apparent relationship with color. Based on the value of Sp.ASM and EM, 7 hues were produced and gray was a single hue. Most of the data were in a normal distribution (p>0.10). ANOVA analysis showed that mean values of Sp.ASM, Sp.EM and Sp.PM were significantly different (p<0.05). The results also showed that Sp.ASM was positively correlated with Sp.EM but the correlation between Sp.ASM and Sp.PM was not significantly different from 0. It is concluded that EM is the major constituent of alpaca hair melanin; there is a significant correlation among ASM, EM and alpaca hair colors, and EM is the most reliable parameter for distinguishing these groups.

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