In vivo Effects of Di-n-butyl Phthalate and Di-2-ehthyhexyl Phthalate on the Nonspecific Defense Mechanism of the Bagrid Catfish, Pseudobagrus fulvidraco

Fatima,강주찬,금유화,지정훈 한국수산과학회 2006 Fisheries and Aquatic Sciences Vol.9 No.1

The Nexus between Capital Structure and Firm Value by Profitability Moderation: Evidence from Saudi Arabia

Nadeem FATIMA(Nadeem FATIMA ),Abdul Rahman SHAIK(Abdul Rahman SHAIK ) 한국유통과학회 2022 The Journal of Asian Finance, Economics and Busine Vol.9 No.9

The current study examines the nexus between the capital structure (debt-equity) and firm value (Tobin’s Q) by including profitability (alternatively Return on Assets (ROA) and Return on Equity (ROE)) as a moderator in the companies of Saudi Arabia. The study sample consists of 102 companies listed on Tadawul (the Saudi Arabian stock exchange) from different sectors of Saudi Arabia during the period 2013 to 2020. The study estimates pooled regression, panel regression with fixed and random effects, and dynamic panel regression models to report the results. The study results report that there is a negative and significant association between capital structure and firm value in model 1, while in models 2 and 3 there is a more negative and significant impact between the two study variables compared to model 1 after the inclusion of interaction variable, i.e. profitability in terms of ROA and ROE. The comparative result shows that the companies of Saudi Arabia hold more debt in their capital structure mix, hence evidencing a decrease in the firm value. The reported results also show that models 2 and 3 are better in explaining the impact of capital structure on firm value due to the interaction of profitability compared to model 1.

Modified Puestow Procedure for Chronic Pancreatitis in a Child Due to Annular Pancreas and Duodenal Duplication: A Case Report

Fatima Safira Alatas,Kouji Masumoto,Toshiharu Matsuura,Antonius Hocky Pudjiadi,Tomoaki Taguchi 대한소아소화기영양학회 2020 Pediatric gastroenterology, hepatology & nutrition Vol.23 No.3

An 18-year-old woman with annular pancreas and duodenal duplication presented with recurrent acute pancreatitis and underwent a resection of duodenal duplication. However, the patient experienced recurrent abdominal pain after resection. Abdominal computed tomography and magnetic resonance imaging showed a dilatation of the peripheral pancreatic duct and stenosis and malformation of both the Wirsung's and Santorini's duct due to multiple stones. The modified puestow procedure was performed. The main pancreatic ducts in the body and tail were opened, and the intrapancreatic common bile duct was preserved. A Roux-en-Y pancreatico-jejunostomy was performed for reconstructing the pancreaticobiliary system after removing the ductal protein plug. The patient experienced no abdominal pain, no significant elevation of the serum amylase and lipase levels, and no stone formation during the 2 years of follow-up. This procedure is considered to be beneficial for pediatric patients with chronic pancreatitis due to annular pancreas and duodenal duplication.

Heterologous Expression of Laccase1 Gene from the Chestnut Blight Fungus Cryphonectria parasitica in Saccharomyces cerevisiae

Fatima HERNANDEZ,Seung-Moon PARK,Beom-Tae KIM,Tae-Geum KIM,Dae-Hyuk KIM 한국생물공학회 2023 한국생물공학회 학술대회 Vol.2023 No.4

Effect of Light-Ions Implantation on Resistivity of GaN Thin Film

Fatima Tuz Johra,정우광 대한금속·재료학회 2014 ELECTRONIC MATERIALS LETTERS Vol.10 No.4

GaN is a very well-known semiconductor because of its properties, making it useful in different types of electronic devices. In electronics applications, the resistivity of the starting materials is very important. In this study, the resistivity of GaN thin films has been investigated upon its modification with ion implantation using both n-type and p-type GaN. Ionic implantation was performed with H, He, and Ar ions. The ion beam energy (60 and 120 keV) and flux (1.0 × 1012 and 1.0 × 1015 cm−2·s−1), as well as post-implantation annealing temperature (100°C - 500°C), were varied to analyze their influence on GaN resistivity. It was observed that the resistivity changed in all samples with the change in ion beam flux and energy. At room temperature, the resistivity of ntype GaN increased from 1.9 × 10−2 to 17.7 × 10−2 Ω·cm. Among all modified samples, He-ion-implanted samples show higher resistivity. During the post-annealing treatment, n-type GaN implanted with He showed more consistency compared to p-type GaN. On the contrary, p-type showed some anomalous character upon postannealing.

Molecular Approach to Allergy Diagnosis and Therapy

Fatima Ferreira,Martin Wolf,Michael Wallner 연세대학교의과대학 2014 Yonsei medical journal Vol.55 No.4

Presently, allergy diagnosis and therapy procedures are undergoing a transition phase in which allergen extracts are being step-by-step replaced by molecule-based products. The new developments will allow clinicians to obtain detailed informationon sensitization patterns, more accurate interpretation of allergic symptoms,and thus improved patients’ management. In this respect, recombinant technology has been applied to develop this new generation of molecule-based allergyproducts. The use of recombinant allergens allows full validation of identity, quantity, homogeneity, structure, aggregation, solubility, stability, IgE-binding and the biologic potency of the products. In contrast, such parameters are extremely difficult to assay and standardize for extract-based products. In addition to the possibilityof bulk production of wild type molecules for diagnostic purposes, recombinanttechnology opened the possibility of developing safer and more efficacious products for allergy therapy. A number of molecule-based hypoallergenic preparationshave already been successfully evaluated in clinical trials, bringing forward the next generation of allergy vaccines. In this contribution, we review the latest developments in allergen characterization, molecule-based allergy diagnosis, and the application of recombinant allergens in therapeutic setups. A comprehensive overview of clinical trials using recombinant allergens as well as synthetic peptidesis presented.

Conception and Manufacturing of a Planar Inductance on NiFe Substrate

Fatima Zohra Medjaoui,Azzedine Hamid,Yacine Guettaf,Pierre Spiteri,Vincent Bley 한국전기전자재료학회 2019 Transactions on Electrical and Electronic Material Vol.20 No.2

The present paper presents the study, realization and characterization of a micro-coil sandwiched using a relatively thick layer of magnetic material. The integration of this micro-coil with as a starting point a set of specifi cations, requires the following steps: Identifi cation and validation of geometric parameters for the calculation of electrical parameters. Losses dissipated as heat in these electronic systems are becoming a major concern for designers. This prompted to take into account the thermal design. The results obtained have allowed to realize a micro-coil micro square planar coil sandwiched shaped between two magnetic materials. Several carried measures focused on the inductance and resistance which are related to the frequency f , the module and phase of the impedance, and the gap g . The operation of these data is used to trace the evolution of theinductance value L s , the quality factor Q and the resistor R s as a function of frequency.

A refined HSDT for bending and dynamic analysis of FGM plates

Fatima Zohra Zaoui,Abdelouahed Tounsi,Djamel Ouinas,Jaime A. Viña Olay 국제구조공학회 2020 Structural Engineering and Mechanics, An Int'l Jou Vol.74 No.1

In this work, a novel higher-order shear deformation theory (HSDT) for static and free vibration analysis of functionally graded (FG) plates is proposed. Unlike the conventional HSDTs, the proposed theory has a novel displacement field which includes undetermined integral terms and contains fewer unknowns. Equations of motion are obtained by using Hamilton’s principle. Analytical solutions for the bending and dynamic investigation are determined for simply supported FG plates. The computed results are compared with 3D and quasi-3D solutions and those provided by other plate theories. Numerical results demonstrate that the proposed HSDT can achieve the same accuracy of the conventional HSDTs which have more number of variables.

Antimicrobial activity and toxicity of Quisqualis indica

Fatima N Jahan,Mohammad S Rahman,Mahboob Hossain,Mohammad A Rashid 경희대학교 융합한의과학연구소 2008 Oriental Pharmacy and Experimental Medicine Vol.8 No.1

The plant Quisqualis indica (Compositae) has ehnopharmcological reputation of being used as a healing agent in Bangladesh. In this study, preliminary screenings were conducted to look at the antimicrobial susceptibility and cytotoxicity of the plant extract. The extractives of the plant were subjected to screening for inhibition of microbial growth by the disc diffusion method. The zones of inhibition demonstrated by the n-hexane, carbon tetrachloride, chloroform and aqueous soluble partitionates of the methanolic extract ranged from 8 - 15 mm, 8 - 18 mm, 12 - 20 mm and 10 - 16 mm, respectively at a concentration of 400 μg/disc. All the extractives were also subjected to brine shrimp lethality bioassay for primary cytotoxicity evaluation. Here, the carbon tetrachloride soluble materials demonstrated the highest cytotoxicity with LC50 of 0.826 μg/ml, while n-hexane, chloroform and aqueous soluble partitionates of the methanolic extract revealed the LC50 of 1.254, 3.866 and 5.366 μg/ml, respectively. This is the first report of the antimicrobial activity and cytotoxicity Q. indica. The plant Quisqualis indica (Compositae) has ehnopharmcological reputation of being used as a healing agent in Bangladesh. In this study, preliminary screenings were conducted to look at the antimicrobial susceptibility and cytotoxicity of the plant extract. The extractives of the plant were subjected to screening for inhibition of microbial growth by the disc diffusion method. The zones of inhibition demonstrated by the n-hexane, carbon tetrachloride, chloroform and aqueous soluble partitionates of the methanolic extract ranged from 8 - 15 mm, 8 - 18 mm, 12 - 20 mm and 10 - 16 mm, respectively at a concentration of 400 μg/disc. All the extractives were also subjected to brine shrimp lethality bioassay for primary cytotoxicity evaluation. Here, the carbon tetrachloride soluble materials demonstrated the highest cytotoxicity with LC50 of 0.826 μg/ml, while n-hexane, chloroform and aqueous soluble partitionates of the methanolic extract revealed the LC50 of 1.254, 3.866 and 5.366 μg/ml, respectively. This is the first report of the antimicrobial activity and cytotoxicity Q. indica.

Comparable Ablation Efficiency of 30 and 100 mCi of I-131 for Low to Intermediate Risk Thyroid Cancers Using Triple Negative Criteria

Fatima, Nosheen,Zaman, Maseeh uz,Zaman, Areeba,Zaman, Unaiza,Tahseen, Rabia Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.3

Background: There is controversy about ablation efficacy of low or high doses of radioiodine-131 (RAI) in patients with differentiated thyroid cancers (DTC). The purpose of this prospective study was to determine efficacy of 30 mCi and 100 mCi of RAI to achieve successful ablation in patients with low to intermediate risk DTC. Materials and Methods: This prospective cross sectional study was conducted from April 2013 to November 2015. Inclusion criteria were patients of either gender, 18 years or older, having low to intermediate risk papillary and follicular thyroid cancers with T1-3, N0/N1/Nx but no evidence of distant metastasis. Thirty-nine patients were administered 30 mCi of RAI while 61 patients were given 100 mCi. Informed consent was acquired from all patients and counseling was done by nuclear physicians regarding benefits and possible side effects of RAI. After an average of 6 months (range 6-16 months; 2-3 weeks after thyroxin withdrawal), these patients were followed up for stimulated TSH, thyroglobulin (sTg) and thyroglobulin antibodies, ultrasound neck (U/S) and a diagnostic whole body iodine scan (WBIS) for ablation outcome. Successful ablation was concluded with stimulated Tg< 2ng/ml with negative antibodies, negative U/S and a negative diagnostic WBIS (triple negative criteria). ROC curve analysis was used to find diagnostic strength of baseline sTg to predict successful ablation. Results: Successful ablation based upon triple negative criteria was 56% in the low dose and 57% in the high dose group (non-significant difference). Based on a single criterion (follow-up sTg<2 ng/ml), values were 82% and 77% (again non-significant). The ROC curve revealed that a baseline sTg level ${\leq}7.4ng/ml$ had the highest diagnostic strength to predict successful ablation in all patients. Conclusions: We conclude that 30 mCi of RAI has similar ablation success to 100 mCi dose in patients with low to intermediate risk DTC. A baseline $sTg{\leq}7.4ng/ml$ is a strong predictor of successful ablation in all patients. Low dose RAI is safer, more cost effective and more convenient for patients and healthcare providers.