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      • Acupuncture Stimulation Alleviates Corticosterone-Induced Impairments of Spatial Memory and Cholinergic Neurons in Rats

        Lee, Bombi,Sur, Bong-Jun,Kwon, Sunoh,Jung, Euntaek,Shim, Insop,Lee, Hyejung,Hahm, Dae-Hyun Hindawi Publishing Corporation 2012 Evidence-based Complementary and Alternative Medic Vol.2012 No.-

        <P>The purpose of this study was to examine whether acupuncture improves spatial cognitive impairment induced by repeated corticosterone (CORT) administration in rats. The effect of acupuncture on the acetylcholinergic system was also investigated in the hippocampus. Male rats were subcutaneously injected with CORT (5 mg/kg) once daily for 21 days. Acupuncture stimulation was performed at the HT7 (Sinmun) acupoint for 5 min before CORT injection. HT7 acupoint is located at the end of transverse crease of ulnar wrist of forepaw. In CORT-treated rats, reduced spatial cognitive function was associated with significant increases in plasma CORT level (+36%) and hippocampal CORT level (+204%) compared with saline-treated rats. Acupuncture stimulation improved the escape latency for finding the platform in the Morris water maze. Consistently, the acupuncture significantly alleviated memory-associated decreases in cholinergic immunoreactivity and mRNA expression of BDNF and CREB in the hippocampus. These findings demonstrate that stimulation of HT7 acupoint produced significant neuroprotective activity against the neuronal impairment and memory dysfunction.</P>

      • 비정렬격자상의 효율적인 고정도 비압축성 유동해석

        이은택(Euntaek LEE),권순은(SunEun Kwon),안형택(Hyung Taek AHN) 한국전산유체공학회 2014 한국전산유체공학회 학술대회논문집 Vol.2014 No.11

        In Shipbuilding fields, there are strong demands for the CFD code which could simulate flow around a complex geometry, for example a marine propeller, perhaps the most complex shape among the parts of ship. In this paper, we discussed the way to simulate flow around a complex geometry with high-order accuracy. We solved the incompressible flow using artificial compressibility formulation. And High-order(>2nd order) solution is obtained by using a high-order solution reconstruction. We simulated various kind of simulations. And we showed the numerical results.

      • KCI등재

        석탄 화력 발전소 배출 미세먼지 측정을 위한 복사전달 방정식 해석

        이은택(Euntaek Lee) 대한환경공학회 2019 대한환경공학회지 Vol.41 No.8

        목적: 본 연구에서는 화력 발전소에서 배출되는 미세먼지 측정을 위한 복사전달 방정식의 해석을 알아보고자 한다. 일반적으로 광산란법이나 광소멸법은 미세먼지 농도 측정에 사용된다. 방법: 이 논문에서는 two-flux approximation을 사용하여 복사전달 방정식을 풀고 무차원 입사 복사를 구하여 보았다. 또한, Lorenz-Mie 이론을 사용하여 미세먼지 입자의 복사특성을 예측하여 보았다. 미세먼지 입자의 크기 분포는 기하 평균 입경 지름 10 nm, 100 nm 그리고 1 μm의 3가지 경우를 고려하였다. 결과 및 토의: 흡수, 산란 단면과 비대칭 인자를 파장의 함수로 예측하고 서로 다른 기하 평균 입경에 대하여 비교하였다. 또한 미세먼지의 질량 농도를 사용하기 위하여 질량 흡수, 산란 단면을 구하였다. 배출에서 무차원 입사복사를 계산하고 질량 농도 10 mg/m3와 50 mg/m3에 대하여 Beer-Lambert와 비교하였다. 결론: 입자의 흡수와 비교하여 산란의 영향이 적을 때 Beer-Lambert 법칙이 타당하다는 것을 알아냈다. 그리고 무차원 입사 복사는 미세먼지의 복사 특성에 큰 영향을 받는다는 사실을 알아냈다. Objectives: This study represents the analysis of radiative transfer equation (RTE) for measurement of particulate matter emitted from coal-fired power plants. Generally, the light extinction method is used to measure the mass concentration of particulate matter. Methods: In this paper, the two-flux approximation is used to solve the radiative transfer equation and obtain the nondimensional incident radiation within emission outlet. Also, the radiation characteristics of the particulate matter are predicted with Lorenz-Mie theory. The particulate matter has three size distributions with geometric mean particle diameters 10 nm, 100 nm and 1 μm. Results and Discussion: Absorption and scattering cross-sections and asymmetric factor are predicted as a function of wavelength and compared with respect to geometric mean particle diameters. Also, mass absorption and scattering cross-sections are predicted for conversion of particulate matter mass concentration. The nondimensional incident radiations at the emission outlet are calculated and compared with that of Beer-Lambert law for mass concentration 10 mg/㎥ and 50 mg/㎥. Conclusions: Beer-Lambert law is valid for low scattering medium compared with absorption of medium. Nondimensional incident radiations at the emission are highly affected by the radiation characteristics of particulate matter.

      • KCI등재

        최근 5년간 국내 소아청소년에서 분리된 Haemophilus influenzae의 항생제 감수성 분석

        이은택 ( Euntaek Lee ),박세라 ( Sera Park ),김미나 ( Mina Kim ),이진아 ( Jina Lee ) 대한소아감염학회 2020 Pediatric Infection and Vaccine Vol.27 No.3

        목적: 최근 β-lactam 계 항생제에 대한 내성을 보이는 Haemophilus influenzae가 증가하고 있다. 본 연구는 최근 5년간 서울아산병원 어린이 병원에서 분리된 H. influenzae 균주의 항생제 내성 양상을 분석하고자 한다. 방법: 2014년 3월부터 2019년 4월까지 서울아산병원 어린이병원을 내원한 18세 미만의 소아청소년 환자의 임상 검체에서 분리된 H. influenzae 균주를 대상으로 항생제 내성 양상을 분석하였다. 결과: 최근 5년간 총 69례의 H. influenzae가 분리되었으며 이들 환자의 연령 중앙값은 5.0 (2.8-8.6)세였다. 총 69례 중 3례(4.3%)가 혈액 배양에서 분리되었으며, 66례(95.7%)가 비침습성 균주로서 대부분 호흡기 검체(59례)에서 분리되었다. 항생제 감수성 분포는 ampicillin (AMP) 감수성/amoxicillin-clavulanate (AMC) 감수성 균주 15례(21.7%), AMP 내성/AMC 감수성 21례(30.4%), AMP 내성/AMC 내성 33례(47.8%)였으며, 최근 5년에 걸쳐 AMP 내성/AMC 내성 균주는 지속적으로 증가하는 경향을 보였다 (2014-2015: 42.1% [8/19], 2016-2017: 46.4% [13/28], 2018-2019: 54.5% [12/22], P for trend=0.342). 2014-2015년에 비해 2018-2019년 기간에는 cefuroxime과 ceftriaxone에 대한 내성률은 각각 31.6%에서 77.3% 및 0.0% 에서 59.1% 로 유의하게 증가하였다(P for trend 0.003 및 <0.001). 결론: 최근 국내의 3차 의료기관에 입원한 소아에서 분리되는 H. influenzae 균주는 AMP및 AMC에 대해 모두 내성인 경우가 흔하며, cefuroxime 및 ceftriaxone 에 대한 내성률이 유의하게 증가하였다. 이러한 균주의 내성 기전 분석과 함께 이의 출현과 확산을 최소화하기 위한 노력이 필수적이다. Purpose: We investigated the trend of antibiotic susceptibility of Haemophilus influenzae over 5 consecutive years. Methods: We analyzed the antibiotic susceptibility of H. influenzae isolated from children aged <18 years, who were admitted to the Asan Medical Center Children's Hospital from March 2014 to April 2019. Antibiotic susceptibility of H. influenzae was determined by the disk diffusion test according to the European Committee on Antimicrobial Susceptibility Testing guidelines. Results: Excluding duplicates, 69 isolates were obtained over the past 5 years. The median age of the patients was 5 years (range, 2.8-8.6 years). The antibiotic susceptibility patterns were as follows: ampicillin (AMP)-susceptible/amoxicillin-clavulanate (AMC)-susceptible (AS/ACS; n=15 [21.7%]), AMP-resistant/AMC-susceptible (AR/ACS; n=21 [30.4%]), and AMP-resistant/AMC-resistant (AR/ACR; n=33 [47.8%]). The prevalence of isolates with AR/ACR phenotype tended to increase from 42.1% in 2014-2015 to 54.5% in 2018-2019 (P=0.342). Compared to 2014-2015, the resistance rates to cefuroxime and ceftriaxone in 2018-2019 increased from 31.6% to 77.3% and from 0.0% to 59.1%, respectively (P=0.003 and P<0.001, respectively). Conclusions: Over the last 5 years, H. influenzae isolates with AR/ACR phenotype and ceftriaxone resistance were frequently observed at our institute. The incidence of resistance to cefuroxime and ceftriaxone has increased significantly.

      • KCI등재
      • KCI등재
      • KCI우수등재

        국내 언론인의 도덕발달단계에 관한 연구

        이은택(Lee Euntaek) 한국언론학회 2002 한국언론학보 Vol.46 No.3

        This study was designed to explore the moral stages of acting Korean newspaper journalists. Lawrence Kohlberg developed six stages for exploring the moral development of youth. The researcher applied Ko hlberg's moral developmental theory to draw a moral map of Korean journalists. Using Q methodology, which emphasizes the subjective side of the subject, the researcher extracted five types of journalists based on the responses from Q sorting. Interpreting the characteristics of each type is as follows. The first group is designated as the Universal Moral Seekers. They value the universal moral principle more than any other groups. Especially, female journalists represent dominant opinion of this group. From their responses, they are believed to reach the final stage of moral development. The second group is called Idealists. They are mostly fresh new journalists just out of college. Six out of nine journalists have no journalism experience. Compared with other groups, they think they should follow the superior's order and value group conformity. The third group is defined as Law Followers. They feel people should follow law and code of ethics and journalists are not the exception. From their points of view, it is natural that journalists who used illegal means be punished. The fourth group is called Realists. They emphasize the good relationship 'kith the sources and colleagues. While expressing the importance of conscience and morality, they think accepting free lunch is permissible. The fifth group is named as Existentialists. Compared with other groups, they cherish individual ethics and conscience. They try to keep their autonomous judgment. In sum, it is good sign that most Korean journalists reached high stages of moral development. However, there are tremendous difference between the attitude and actual behavior. To encourage moral thinking and behavior, there should be more media ethics courses and workshop for Korean journalists.

      • KCI우수등재

        비만의 사회적 구성

        이은택(Euntaek Lee),노성종(Sungjong Roh),최은경(Eunkyoung Choi),강충구(Chungku Kang) 한국언론학회 2010 한국언론학보 Vol.54 No.2

        Obesity is a daily life matter. However, to understand its cause requires beyond common knowledge; It demands scientific knowledge. Hence, news about obesity might exert significant influences on public opinion towards related governmental policy by shaping and swaying people's perception about obesity. The authors tried to uncover how Korean news media frame obesity for the past 20 years. In particular, the current study conceptually divides past 20 years period into three distinct phases, which are period of pre-IMF bailout, post-IMF bailout, and well-being boom, in analysing the quantitative(frequency of coverages) and qualitative features(format and content) of news about obesity, including analysis of between(print v. broadcast media) and within(both conservative v. liberal news outlets and public service v. commercial broadcasting) differences of news media coverages. Findings indicate that the news coverage of obesity varies depending on its time phase when it is reported and media outlets where it is reported. Theoretical and practical implications of the study and suggestions for future studies are discussed.

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