혈당 측정에 있어서 반사광 비색법과 전기 화학 전극법의 비교

황유성,이도훈,우재근 충북대학교 의과대학 충북대학교 의학연구소 1995 忠北醫大學術誌 Vol.5 No.1

당뇨병환자에서 적절한 혈당을 유지하기 위한 목적으로 시험지봉 검사 방법이 1970년대 초 처음으로 개발된 이후 많은 자가 혈당기들이 고안되어 사용되고 있으며, 대부분이 반사광 비색법을 이용한 자가 혈당 측정기로 현재 국내에는 Glucometer(Ames), Glucoscan(Eiken), One TouchTRM Ⅱ(Lifescan), Accu-check Ⅲ(BM)등이 사용되고 있다. 저자들은 본원에서 이미 사용하고 있었던 반사광 비색법을 이용한 시험지봉으로 LIFESCAN사의 One TouchTM Ⅱ와 전기 화학 전극법을 이용한 Medisense사의 CompanionTM 2에 대하여 정밀도, 직선성, 비교방법과의 상관관계 및 혈액량과 헤마토크리트에 의한 영향, 관찰자간의 변이, 항응고제가 미치는 영향 등 측정에 영향을 미치는 여러 인자들에 대하여 평가를 시행하였다. 검사일내 정밀성(within day precision)은 두 기기 모두 5% 정도이었고, 검사일간 정밀성(day-to-day precision)은 CompanionTM 2가 3.14%∼6.53%, One touchTM Ⅱ가 4.69%∼8.13%의 변이계수를 보였다. 두 기기 모두 직선성이나 비교방법과의 상관관계가 우수하였다. CompanionTM 2와 One touchTM Ⅱ사이의 상관관계는 y=1.040x+21.679, r=0.9716이었다. 두 기기 모두 혈액량, 관찰자, 항응고제에 의해서는 영향을 받지 않았으며, 헤마토크리트에 의해서는 헤마토크리트가 낮을 때는 높은 혈당치를, 헤마토크리트가 높을 때는 낮은 혈당치를 나타냈다. The purpose of this study is to assess two monitors of blood glucose : One touch?? Ⅱ(Lifescan Inc.), which is using reagent strips by reflectance photometry and CompanionTM 2(Medisense Inc.), which is using electrochemical electrode method. Glucose was determined on capillary and venous blood samples from 70 adult diabetics by three different methodologies : One touchTM Ⅱ, CompanionTM 2 portable glucose meters (capillary) and the Hitachi 7150 analyzer(venous), which is using hexokinase method. In within-run precision studies for One touchTM Ⅱ and CompanionTM 2, coefficient variations (CVs, %) were 1.92∼5.09, 2.95∼4.79 at three different levels, respectively. In between-day percision studies for One touchTM Ⅱ and CompanionTM 2, CVs(%) were 4.69∼8.13, 3.14∼6.53 at three different levels, respectively. The linearity studies revealed r=0.9996 in One touch?? Ⅱ, r=0.9977 in CompanionTM 2, which were satisfactory. Correlation equation and coefficient for results by One touchTM Ⅱ and CompanionTM 2 vs those by hexokinase method(x) were : y=0.8087x-8.9566(r=0.9824) for One touchTM Ⅱ, y=0.8885x+4.4992(r=0.9807) for CompanionTM 2, which were satisfactory. The glucose levels were falsely high at low hematocrit concentration and falsely low at high hematocrit concentration in both monitors. The volume of blood applied to the test strips is not critical. We concluded that "One touchTM Ⅱ" using reagent strip by reflectance photometry and "Companion?? 2" using electrochemical electrode method is suitable for self monitoring of blood glucose.

Optical Third-Harmonic Generation of Poly(2-Bromo-1,4-phenylenevinylene)

Hwang Do-Hoon,Lee Jeong-Ik,Lee Minyung,Shim Hong-Ku Korean Chemical Society 1994 Bulletin of the Korean Chemical Society Vol.15 No.1

Weakly electron withdrawing bromine substituted poly(2-bromo-1,4-phenylenevinylene) (PBrPV) was synthesized th-rough water-soluble precursor method. The linear and nonlinear optical properties of PBrPV were compared with those of poly(1,4-phenylenevinylene) (PPV). The third-order nonlinear optical susceptibility, X^{(3)}$, was measured by using third-harmonic generation (THG) technique at 1907 nm, fundamental wavelength. The calculated $X^{(3)}$ values of PPV and PBrPV were 3${\times}$ 10$^{-12}$ esu and 2${\times}$10$^{-12}$ esu, respectively.

Synthesis and characterization of polystyrene brushes for organic thin film transistors.

Hwang, Do-Hoon,Nomura, Akihiro,Kim, Jeongsik,Kim, Ji-Hoon,Cho, Hyunduck,Lee, Changhee,Ohno, Kohji,Tsujii, Yoshinobu American Scientific Publishers 2012 Journal of Nanoscience and Nanotechnology Vol.12 No.5

<P>We synthesized and characterized polystyrene brushes on a silicon wafer using surface-initiated atom transfer radical polymerization. The thickness of the polymer brush was controlled by adjusting the reaction time. We investigated monomer conversion as well as the molecular weight and density of the polymer brushes. When the monomer conversion reached 100%, the number-average molecular weight and film thickness reached 135,000 and 113 nm, respectively. The estimated densities of the synthesized polystyrene brushes were in the range 0.34-0.54 chains/nm2, high enough to be categorized in the 'concentrated brush' regime. The synthesized polymer brush was used as an insulating layer in an organic thin-film transistor. Organic thin-film transistors were fabricated using pentacene as an active p-type organic semiconductor and a polystyrene brush on a SiO2 layer as a gate dielectric. The pentacene based organic thin-film transistor with the polystyrene brush exhibited a field-effect mobility microFET of 0.099 cm2/(V x s).</P>

Green Light-Emitting Diodes from Poly(2-dimethyloctylsilyl-1.4-phenylenevinylene)

Do Hoon Hwang,Sung Tae Kim,Hong Ku Shim,Andrew B. Holmes,Richard H. Friend 한국고분자학회 1997 한국고분자학회 학술대회 연구논문 초록집 Vol.1997 No.4

Light-emitting devices with polymer-organic heterostructure

Do, Lee-Mi,Hwang, Do-Hoon,Choi, Kang-Hoon,Lee, Hyang-Mok,Jung, Sang-Don,Zyung, Taehyoung Optical Society of Korea 1997 Current Optics and Photonics Vol.1 No.2

Highly quantum efficient and multi-color emissible polymer light emitting devices have been realized utilizing poly (1-dodecyloxy-4-methyl-1, 3-phenylene)(2, 5"-terthienylene)(hereafter, mPTTh polymer) as an emitting layer and tris(8-hydroxyquinoline) aluminum (Alq3) as an electron transport layer. A single layer EL device of mPTTh polymer emits orange-colored light. EL efficiency increases as the thickness of Alq3 layer increases, but the emission color becomes visually broad when the Alq3 layer thickness is greater than 30nm since the relative peak intensity of green EL from Alq3 layer grows. EL color is changed from orange to greenish orange as the thickness of Alq3 layer grows. EL color is changed from orange to greenish orange as the thickness of Alq3 layer increases. EL efficiency of the double layer device was greatly enhanced by 3000 times compared with that of a single layer device. Alq3 layer in device acts as a hole blocking electron transporting layer and an emitting layer as a function of the thickness of Alq3 layer.ayer.

Synthesis and characterization of a solution processible deep blue light-emitting molecule composed of fluorene and pyrene units

Hwang, Do-Hoon,Lee, Sunyoung,Kim, Ji-Hoon,Lee, Jonghee Elsevier 2012 Current Applied Physics Vol.12 No.suppl1

<P><B>Abstract</B></P><P>A solution processible deep blue light-emitting molecule composed of pyrene and dialkylfluorene units, 1,6-bis(9,9′-dioctylfluorene-2-yl)pyrene (BDOFP) was synthesized and characterized. The synthesized compound was soluble in common organic solvents and the solution gave a smooth thin film after spin coating. The compound was characterized by using thermogravimetric analysis (TGA), differential calorimetry (DSC), UV–visible spectroscopy, fluorescence spectroscopy and cyclic voltammetry. The maximum UV–visible absorption and PL emission of BDOFP thin film were more red-shifted than those of BDOFP solution due to strong intermolecular interaction between flat segments. To improve color purity and film stability BDOFP was doped to a well-known charge-transporting polymer, poly(<I>N</I>-vinylcarbazole) (PVK). BDOFP thin film showed it maximum PL at 457 nm but the thin films of BDOFP doped PVK films showed it at 443 nm. Organic light-emitting diodes were fabricated with the simple structure of ITO/PEDOT:PSS/emitter/BmPyPB/LiF/Al configuration. BDOFP or three kinds of BDOFP:PVK blends with different ratios (10:90, 30:70, 50:50 by weight) were used as the emissive layers and [1,3-bis(3,5-dipyrid-3-yl-phenyl)benzene] (BmPyPB) as the electron-transporting layer. All of light-emitting devices showed their electroluminescence in blue region of spectrum, especially EL using BDOFP: PVK (1:9) showed a deep-blue light emission with CIE coordinates of (0.14, 0.07). Maximum brightness, external quantum efficiency and current efficiency of the device were 500 cd/m<SUP>2</SUP>, 0.7% and 0.44 cd/A, respectively.</P>

Synthesis and EL Properties of Blue Light-emitting Poly(arylenevinylene)s

Hwang, Do-Hoon The Korean Infomation Display Society 2002 Journal of information display Vol.3 No.1

A series of fully conjugated polymers containing new arylenevinylene units were synthesized and their light-emitting properties were investigated. A bisphosphonate containing tetraphenyl group was made to react with three different dialdehyde monomers to produce fully conjugated alternating copolymers. The photoluminescence (PL) and the electroluminescence (EL) peak wavelengths of the polymers were varied from 500 nm to 460 nm depending on the polymer structure. Single layer EL devices using the polymers as an emissive layer have been fabricated. The single layer EL devices became visible between 12-22 V and emitted blue light.

Organic light-emitting diode using a new DCM derivative as an efficient orange-red doping molecule

Do-Hoon Hwang,Jong-Don Lee,Moon-Jae Lee,Changhee Lee 한국물리학회 2005 Current Applied Physics Vol.5 No.3

A new DCM derivative containing the phenoxazine moiety (DCPXZ) has been synthesized for use as a red uorescent dyemolecule in organic light-emitting diodes (OLEDs). The photoluminescence and electroluminescence properties of DCPXZ wereexamined. The maximum photoluminescence of DCPXZ in chloroform solution (10. 5 mol) was observed at 616 nm. EL deviceswere fabricated with the structure ITO/PEDOT-PSS/Cu-PC(15 nm)/a-NPD(45 nm)/Alq3:DCPXZ(30 nm)/Alq3(30 nm)/LiF(0.5 nm)/Al. The maximum EL emission for the 2.0% DCPXZ-doped device was at 608 nm with CIE coordinates (0:57;0:42). The EL deviceexhibited a maximum brightness of 15,000 cd/m2 at 19.4 V and a power eciency of 1.04 lm/W at a luminance of 100 cd/m2..

Synthesis and Light-emitting Properties of Poly (fluorene) Copolymers Containing EDOT Comonomer

Hwang, Do-Hoon,Park, Moo-Jin,Lee, Ji-Hoon The Korean Infomation Display Society 2004 Journal of information display Vol.5 No.4

A series of statistical random copolymers of dioctylfluorene (DOF) and 3,4-ethylenedioxythiophene (EDOT) were synthesized by Ni (0) mediated polymerization and their light-emitting properties were compared with poly (9,9-di-n-octylfluorene) (PDOF). The synthesized polymers were characterized using UV-vis spectroscopy, TGA, photoluminescence (PL) & electroluminescence (EL) spectroscopy and by conducting molecular weight studies. The resulting polymers were found to be thermally stable and readily soluble in organic solvents. The UV-visible absorption and PL emission spectra of the copolymers were gradually red-shifted as the fraction of EDOT in copolymers increased. Light-emitting devices were fabricated in an ITO (indium-tin oxide)/PEDOT/polymer/Ca/Al configuration. Interestingly, the EL spectra of these devices were similar to the PL spectra of the corresponding polymer film. However, the EL devices constructed from the copolymer showed more than 10 times higher efficiency level than the devices constructed from the PDOF homopolymer. This higher efficiency is possibly the result of better charge carrier balance in the copolymer systems due to the lower HOMO levels of the copolymers in comparison to that of PDOF homopolymer.

Optimal economic fishing efforts in Korean common octopus <i>Octopus minor</i> trap fishery

KIM, Do Hoon,AN, Heui Chun,LEE, Kyoung Hoon,HWANG, Jin -wook Blackwell Publishing Asia 2008 Fisheries Science Vol.74 No.6

<P>ABSTRACT</P><P>The Korean Government is in the process of establishing a plan for managing fishing effort by setting up the maximum fishing gear usage per fishery type for the recovery of fishery resources. This will aid settlement of disputes between fishery sectors over fishing gears, and the stability of fishing business conditions. Especially in the setting up of the maximum fishing gear usage, economic standards as well as biological standards are being considered as significant factors to promote the sustainable and economically viable development of fisheries. This study is, thus, to analyze the optimal economic fishing gear usage (E<SUB>MEY</SUB>) as the most economically efficient usage for the common octopus trap fishery, one of the most controversial sectors in establishing maximum fishing gear usage. Data from logbooks per trip were used for estimation of E<SUB>MEY</SUB> per trip because it was considered there were limitations of data available for analyses. As a finding drawn from the analyses, the E<SUB>MEY</SUB> of common octopus trap vessels per trip has to be decreased by approximately 13%. That is, reducing the trip trap usage up to the level of E<SUB>MEY</SUB> can lead to the reduction of trip fishing costs, thereby resulting in increased trip profits.</P>