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박희윤,이종만 성신여자대학교 기초과학연구소 2001 基礎科學硏究誌 Vol.19 No.-
The surface pressure - mean molecular area isotherms for valinomycin, a cyclic dodecadepsipeptide ionophore antibiotic, at the air/water interface have been investigated under various subphases and temperatures using Langmuir - type Film Balance in order to obtain the physical properties of monolayer of horizontally oriented valinomycin which is one component of mitochondria membrane. Pure valinomycin apparently forms reasonably stable monolayer at various temperatures. These curves give the extrapolated mean molecular area which is 383.77Å2 at 33℃, monolayer compressibility which is 0.0264cm/dyne and collapse pressure which is 16.06mN/m at 33℃. As the KCl concentration in subphase was increased more than 1.0M, an inflection, phase transition in the valinomycin force-area curve occured at successively lower surface pressure and higher mean molecular area. In contrast, Li+, Na+ and Cs+ ions showed no phase transition. When valinomycin complexes a cation, K+ at the membrane/water interface, it undergoes a rearrangement that is evident from a decrease in mean molecular area of approximately 15∼ 20Å2. And also the surface pressure versus mean molecular area curves of the mixed monolayer of valinomycin with L-α-Dipentadecanoyl Phosphatidylcholine (DPPC) were obtained at various compositions. By addition of DPPC, it was observed that the mean molecular area of mixed monolayer becames somewhat smaller than the value to be calculated theoretically. An equimolar mixture of valinomycin and DPPC gave an isotherm contour that indicates considerable condensation.
이규윤,김용배,이영만,양순재,박종섭 大韓成形外科學會 1991 Archives of Plastic Surgery Vol.18 No.1
Significant soft-tissue defects in the lower extremity including the tibia and the foot are best managed with free skin-muscle of skin-grafted free muscle transfers. While free flap donor sites useful for lower exremity reconstruction include the latissimus dorsi, the rectus abdominis, the gracilis, and the scapular flaps, the latissimus dorsi seems ideal. This muscle has a reliably long vascular pedicle of wide diameter, making microsurgical anastomosis of the thoracodorsal vessels straightforward. Because it is so large, it can cover virtually and size defect. Furthermore, its flat configuration makes it especially easy to fold on itself to that it can be used to closure wounds with complex three-dimensional geometry and dead space. Although the gracilis and rectus abdominis muscles have their roles, in most cases the latissimus dorsi should serve well. We described technical considerations in each case and the advantages of free latissimus dorsi myocutaneous flap on the reconstruction of the soft tissue defect in the lower extremity.
ATYPICAL MESOBLASTIC NEPHROMA 1례
박만수,이중화,윤율로,설종구 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.1
Atypical mesoblastic nephroma is a rare infantile renal tumor that may behave aggressively in older infants. The features that distinguish atypical mesoblastic nephroma from congenital mesoblastic nephrorma are as follows; (1) atypical gross features consisting of one or more of the follwing: flesh areas, foci of hemorrhage, necrosis, involvement of adjacent structures; and (2) high cellularity and mitotic index. Treatment is not established whether additional modes of therapy are indicated in completely resected atypical mesoblastic nephroma. A close and regular periodic follow-up is indicated in all cases of atypical mesoblastic nephroma. A case of atypical mesoblastic nephroma in 45-day-old-male is presented with brief review of literatures.
金瑩洙,河泰原,朴滿洙,姜瞬求,李重禾,尹栗老,薛鍾求 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.2
Rhabdomyosarcoma, which is a very rare and highly malignant disease in urologic field, has three categories-pleomorphic, alveolar, embryonal, and may arise from any part of the body that contains embryonal mesenchyme, whether striated muscle tissue is present or not. The common site in the genitourinary tract are prostate, bladder, and vagina. Herein we experienced a rhabdomyosarcoma of the pelvic cavity and reviewed literature briefly.
간장 ( 肝臟 ) 및 담도 ( 膽道 ) : 간성뇌증에 대한 경구용 Branched - Chain Amino Acid ( AminolebanR EN ) 의 임상 효과
윤종만(Chong Man Yoon),최흥재(Heung Jai Choi),기춘석(Choon Suhk Kee),문한규(Han Kyu Moon),이창홍(Chang Hong Lee),김부성(Boo Sung Kim),이상인(Sang In Lee),장린(Rin Chang),이창돈(Chang Don Lee),류종선(Jong Sun Rew),곽규식(Kyu Sik Kwak 대한소화기학회 1991 대한소화기학회지 Vol.23 No.2
N/A The effects of oral branched-chain amino acids (Aminoleban EN) were investigated in 44 patients (male: 33, famale: 11, Mean age: 50.6 +- 8.4 years old) with decompensated liver cirrhosis and hepatic encephalopathy or history thereof in a multicenter collabo-ative clinical study. The following results were obtained. 1) Significant improvements were observed in indicators of neuropsychiatric symptoms such as asterixis, ability to make caIculations, number connection test times, encephalopathic grade and performance status among patients. 2) Plasma levels of branched-chain amino acids elevated significantly in the second week of treatment, and those of aromatic amino acids were in the decreasing trend after treatment, Fischers ratio were significanthy improved. 3) Serum levels of albumin in the patients with hypoalbuminemia (less than 3.0 gm%) were significantly elevated. 4) Adverse reactions reported in 3 cases (6.8%) out of 44 cases were abdominal pain, vomiting and abdominal distension with massive ascites. These results suggested that the supplementation of the diet with oral branched-chain amino acids may be beneficial effects in the patients with hepatic encephalopathy through the improvement of encephalopathy and nutritional status.
윤종만 ( Chong Man Yoon ),조국현 ( Kook Hyun Cho ),조영구 ( Young Koo Cho ),김연길 ( Yun Kil Kim ),이태희 ( Tae Hee Lee ) 대한내과학회 1970 대한내과학회지 Vol.13 No.2
A case of acquired diaphramatic hernia with gastric volvulus is presented, and clinical and etiological aspect are briefly reviewed. Forty-eight year old man was admitted with complaint of repeated vomiting, hematemesis, severe constant epigastric pain and
윤종만 ( Chong Man Yoon ),박승조 ( Seung Jo Park ),이찬헌 ( Chan Hun Lee ),김봉한 ( Bong Han Kim ) 대한내과학회 1973 대한내과학회지 Vol.16 No.2
A 47 year-old male was hospitalized for longstanding diabetes with peripheral neuropathy which had been difficult to control with insulin over seven years. Regular insulin and phenformin were given according to the urine sugar determinations. During hospit