http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Frontispiz: A Cytoprotective and Degradable Metal–Polyphenol Nanoshell for Single‐Cell Encapsulation
Park, Ji Hun,Kim, Kyunghwan,Lee, Juno,Choi, Ji Yu,Hong, Daewha,Yang, Sung Ho,Caruso, Frank,Lee, Younghoon,Choi, Insung S. WILEY‐VCH Verlag 2014 Angewandte Chemie Vol.126 No.46
<P><B>Nanoschalen</B> F. Caruso, Y. Lee, I. S. Choi und Mitarbeiter beschreiben in ihrer Zuschrift auf S. 12628 ff., dass einzelne Hefezellen durch die Bildung einer Nanoschale aus Gerbsäure und Fe<SUP>III</SUP>‐Ionen geschützt werden können.</P>
Cho, Woo Kyung,Kang, Kyungtae,Kang, Gyumin,Jang, Min Jee,Nam, Yoonkey,Choi, Insung S. WILEY‐VCH Verlag 2010 Angewandte Chemie Vol.122 No.52
<P><B><I>Die Strukturweite des nanostrukturierten Substrats</I></B> steuert das Wachstum von Nervenzellen in vitro. In ihrer Zuschrift auf S. 10312 ff. zeigen I. S. Choi, Y. Nam et al., dass primäre Hippocampusneuronen auf anodisiertem Aluminiumoxid mit 400 nm Strukturweite viel schneller wachsen – im Zeitraum von einigen Tagen – als auf Oberflächen mit 60 nm Strukturweite.</P>
Organic/inorganic double-layered shells for multiple cytoprotection of individual living cells
Hong, Daewha,Lee, Hojae,Ko, Eun Hyea,Lee, Juno,Cho, Hyeoncheol,Park, Matthew,Yang, Sung Ho,Choi, Insung S. Royal Society of Chemistry 2015 Chemical science Vol.6 No.1
<▼1><P><I>S. cerevisiae</I> encapsulated with a poly(norepinephrine)/silica double-layered shell showed multiple resistance to enzymatic attack, desiccation, and UV-C irradiation. The biochemical response of the encapsulated yeast may also contribute to the UV-C resistance.</P></▼1><▼2><P>The cytoprotection of individual living cells under <I>in vitro</I> and daily-life conditions is a prerequisite for various cell-based applications including cell therapy, cell-based sensors, regenerative medicine, and even the food industry. In this work, we use a cytocompatible two-step process to encapsulate <I>Saccharomyces cerevisiae</I> in a highly uniform nanometric (<100 nm) shell composed of organic poly(norepinephrine) and inorganic silica layers. The resulting cell-in-shell structure acquires multiple resistance against lytic enzyme, desiccation, and UV-C irradiation. In addition to the UV-C filtering effect of the double-layered shell, the biochemical responses of the encapsulated yeast are suggested to contribute to the observed UV-C tolerance. This work offers a chemical tool for cytoprotecting individual living cells under multiple stresses and also for studying biochemical behavior at the cellular level.</P></▼2>
Choi, Won Suk,Choi, Insung S.,Lee, Jungkyu K.,Yoon, Kuk Ro Elsevier 2015 Materials chemistry and physics Vol.163 No.-
<P><B>Abstract</B></P> <P>We demonstrated a new type of visible light-induced photocatalyst, comprising fluorescein molecules, TiO<SUB>2</SUB>, and gold nanoparticles anchored onto polymer fibers. The synthesized fiber composite was fully characterized by thermogravimetric analysis, scanning electron microscopy, transmission electron microscopy, FT-IR spectroscopy, contact angle measurement, and fluorescence microscopy. Under sunlight and visible light irradiation, the photocatalytic activity of the tricomponent system showed 2–3 times greater photodegradation efficiency for methylene blue than a representative photocatalyst, Degussa P25.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Synthesis of a novel composite, polymer fiber/organic dye/TiO<SUB>2</SUB>/gold nanoparticles. </LI> <LI> The composite was characterized by TGA, SEM, TEM, and fluorescence microscopy. </LI> <LI> Improved visible light photocatalytic activity of the sythesized novel composite. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>PSS/PAH-FITC/TiO<SUB>2</SUB>/AuNP composite demonstrated 2–3 times greater visible light photodegradation efficiency for methylene blue than a representative photocatalyst, Degussa P25.</P> <P>[DISPLAY OMISSION]</P>
Cytoprotective Silica Coating of Individual Mammalian Cells through Bioinspired Silicification
Lee, Juno,Choi, Jinsu,Park, Ji Hun,Kim, Mi‐,Hee,Hong, Daewha,Cho, Hyeoncheol,Yang, Sung Ho,Choi, Insung S. WILEY‐VCH Verlag 2014 Angewandte Chemie Vol.126 No.31
<P><B>Abstract</B></P><P>The cytoprotective coating of physicochemically labile mammalian cells with a durable material has potential applications in cell‐based sensors, cell therapy, and regenerative medicine, as well as providing a platform for fundamental single‐cell studies in cell biology. In this work, HeLa cells in suspension were individually coated with silica in a cytocompatible fashion through bioinspired silicification. The silica coating greatly enhanced the resistance of the HeLa cells to enzymatic attack by trypsin and the toxic compound poly(allylamine hydrochloride), while suppressing cell division in a controlled fashion. This bioinspired cytocompatible strategy for single‐cell coating was also applied to NIH 3T3 fibroblasts and Jurkat cells.</P>