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      • Treatment of fever with traditional Chinese medicine according to Zheng on cancer patients (based on case reports)

        Peng Cao,Lan-Ying Liu,Xue-Ting Cai,Xiao-Ning Wang,Jie-Ge Huo,Zhong-Ying Zhou 셀메드 세포교정의약학회 2012 셀메드 (CellMed) Vol.2 No.2

        Fever in cancer patients is often due to the following causes: evil qi and toxity stagnancy, disorders of qi and blood, deficiencies of zang and fu organs, and the disorder of yin and yang. The treatments given to cancer patients with a fever are according to five: (a) Excessive inner heat and toxicants: remove heat and the toxicant, induce purgation. We use Cheng-Qi-Tang plus Qing-Wen-Bai-Du-Yin. (b) Tangle of damp and heat, and qi stagnancy: remove damp and heat, smooth the qi channel. We use Gan-Lu-Xiao-Du-Dan or San-Ren-Tang. (c) Obvious blood and heat stagnancy: remove heat and blood stasis. We use Xue-Fu-Zhu-Yu-Tang. (d) Deficiency of spleen qi, inner heat caused by a yin deficiency: nourish spleen qi and yin to remove the inner heat. We use Bu-Zhong-Yi-Qi-Tang or Xiao-Jian-Zhong-Tang. (e) Prominent yin deficiency and hectic fever: replenish yin and remove inner heat. We use Qing-Hao-Bie-Jia-Tang or Chai-Qian-Mei-Lian-San. The pathogenesis of fever in cancer patients is complicated. We can see both deficiency and excess in one differentiation. Therefore, we must make sure of it, then we can get the most effective treatment.

      • SCIEKCI등재

        Four-year changes in central fatness, risk of diabetes, and metabolic control in older adults: a cohort study with mediation analysis

        ( Xue Cai ),( Dan Luo ),( Shuling Liu ),( Ruxue Li ),( Yanhui Lu ),( Mingzi Li ),( Shanhu Qiu ) 대한내과학회 2022 The Korean Journal of Internal Medicine Vol.37 No.1

        Background/Aims: Older adults are vulnerable to central obesity, while the association of changes in central fatness with risk of diabetes and metabolic control has not been investigated among this particular population. This study was aimed to address these issues. Methods: A total of 1,815 adults aged ≥ 60 years without diabetes at baseline were followed for 4 years. Incident diabetes was ascertained based on plasma glucose, hemoglobin A1c, medical history, and/or the use of anti-diabetic drugs. Central fatness was assessed by waist circumference (WC), waist-height ratio (WHtR), and body roundness index (BRI). Logistic regression analyses were used to assess the association of changes in central fatness with risk of diabetes, along with dose-response and mediation analyses. Results: During the 4-year follow-up, 177 participants developed diabetes. The risk of diabetes was increased by 42%, 41%, and 40% per 1 standard deviation increases in WC, WHtR, and BRI, respectively, in multivariable-adjusted models (all p < 0.01). Moreover, these relationships were all linearly-shaped (all p<sub>nonlinearity</sub> ≥ 0.11). Increases in WC, WHtR, and BRI correlated with increases in hemoglobin A1c, triglycerides-and-glucose index, triglycerides, white blood cell, and C-reactive protein (all p ≤ 0.04). Yet only changes in hemoglobin A1c and triglycerides-and-glucose index were identified as the possible mediators for risk of diabetes, with their mediating effect being about 35% and 21%, respectively. Conclusions: Increases in central fatness were related to elevated risk of diabetes, and this association might be partly explained by the worsening of glycemic control and insulin resistance in older adults.

      • KCI등재

        Association of Perceived Stress With Depression Among Vaccinated Healthcare Workers During the SARS-CoV-2 Variant Outbreak: The Mediating Role of Compassion Fatigue

        Cai Xue,Li Guohong,Feng Haixia,Wang Xiaoyan,He Lijun,Luo Dan,Xu Cuirong,Huang Yingzi,Qiu Shanhu 대한신경정신의학회 2023 PSYCHIATRY INVESTIGATION Vol.20 No.4

        Objective Depression was common during coronavirus disease-2019 (COVID-19) pandemic, while the association of perceived stress with depression among vaccinated healthcare workers has not been investigated. This study aimed to address this issue.Methods We included a total of 898 fully vaccinated healthcare workers during the outbreak of severe acute respiratory syndrome coronavirus 2 Delta variant in Nanjing, 2021. Depression was ascertained by Patient Health Questionnaire-9, with a cut-off score of ≥5 indicative of mild-to-severe depression. Perceived stress, resilience, and compassion fatigue were assessed by Perceived Stress Scale-10, Resilience Scale-25, and Professional Quality of Life Scale version-5, respectively. Logistic regression analyses were used to estimate the odds ratio (OR) and 95% confidence interval (CI), along with subgroup and mediation analyses.Results The prevalence of mild-to-severe depression was 41.1% in vaccinated healthcare workers. The odd of mild-to-severe depression was increased with higher perceived stress. Compared with vaccinated healthcare workers with the lowest tertile of perceived stress, those with the highest tertile had increased odds of mild-to-severe depression by 120% (OR 2.20, 95% CI 1.46 to 3.31) after multivariable-adjustment. However, perceived stress was not associated with mild-to-severe depression in vaccinated healthcare workers with strong resilience, but was in those with weak resilience (p<sub>interaction</sub>=0.004). Further analysis showed that compassion fatigue mediated the relationship between perceived stress and mild-to-severe depression, with a mediating effect of 49.7%.Conclusion Perceived stress was related to an increased odd of mild-to-severe depression in vaccinated healthcare workers during COVID-19 pandemic, and this relationship might be explained by compassion fatigue.

      • KCI등재

        DFT Study for Adsorption and Decomposition Mechanism of Trimethylene Oxide on Al(111) Surface

        Cai-Chao Ye,Jie Sun,Fengqi Zhao,Siyu Xu,Xue-Hai Ju 대한화학회 2014 Bulletin of the Korean Chemical Society Vol.35 No.7

        The adsorption and decomposition of trimethylene oxide (C3H6O) molecule on the Al(111) surface were investigated by the generalized gradient approximation (GGA) of density functional theory (DFT). The calculations employed a supercell (6 × 6 × 3) slab model and three-dimensional periodic boundary conditions. The strong attractive forces between C3H6O molecule and Al atoms induce the C-O bond breaking of the ring C3H6O molecule. Subsequently, the dissociated radical fragments of C2H6O molecule oxidize the Al surface. The largest adsorption energy is about −260.0 kJ/mol in V3, V4 and P2, resulting a ring break at the C-O bond. We also investigated the decomposition mechanism of C3H6O molecules on the Al(111) surface. The activation energies (Ea) for the dissociations V3, V4 and P2 are 133.3, 166.8 and 174.0 kJ/mol, respectively. The hcp site is the most reactive position for C3H6O decomposing.

      • KCI등재

        Robust estimation with a modified Huber’s loss for partial functional linear models based on splines

        Cai Xiong,Xue Liugen,Lu Fei 한국통계학회 2020 Journal of the Korean Statistical Society Vol.49 No.4

        In this article, we consider a new robust estimation procedure for the partial functional linear model (PFLM) with the slope function approximated by spline basis functions. This robust estimation procedure applies a modifed Huber’s function with tail function replaced by the exponential squared loss (ESL) to achieve robustness against outliers. A data-driven procedure is presented for selecting the tuning parameters of the new estimation method, which enables us to reach better robustness and efciency than other methods in the presence of outliers or non-normal errors. We construct robust estimators of both parametric coefcients and function coefcient in the PFLM. Moreover, some asymptotic properties of the resulting estimators are established. The fnite sample performance of our proposed method is studied through simulations and illustrated with a data example.

      • KCI등재

        Experimental Investigation of Measurement Error in Networked Resistors Arrays Based on Zero Potential Method

        Xue-Feng Zhang,Anjiang Cai,Yulong Zhao 한국정밀공학회 2018 International Journal of Precision Engineering and Vol.19 No.4

        This paper provides a comprehensive study on the zero potential method for restriction of the crosstalk-based measurement error in network resistor arrays. We introduce four circuits with different architectures based on the zero potential method to comparatively study the effect of the switches on-resistance on the measurement error. Moreover, the effect of the operational amplifiers with different specifications on the measurement error will be investigated. The results show that the measurement error introduced by the onresistance of the switches can be effectively suppressed by inserting a buffer between the sensing elements and the switches on each driven electrode, and utilizing the virtual ground of the trans-impedance amplifier on each scanned electrode. We will show that, the efficiency of the circuits on elimination of the measurement error may be improved by employing high precision operational amplifiers.

      • SCIESCOPUSKCI등재

        Decomposition Properties of Trifluoroiodomethane under Discharges and Interruptions

        Cai, Fan-Yi,Tan, Dong-Xian,Zhou, Bai-Jie,Xue, Jian,Xiao, Deng-Ming The Korean Institute of Electrical Engineers 2018 Journal of Electrical Engineering & Technology Vol.13 No.6

        This paper is devoted to detecting decomposition characteristics of Iodotrifluoromethane ($CF_3I$) under alternating current (AC) discharges or load current interruptions. The decomposition products are measured utilizing chromatography-mass spectroscopy. It is found that less than 1% $CF_3I$ gas decomposed after several interruptions at load current of 200 A or hundred times of AC discharges. However, under interruptions at a current of 400 A, more than 95% $CF_3I$ gas decomposed into carbon tetrafluoride ($CF_4$) and hexafluoroethane ($C_2F_6$). The equilibrium compositions based on Gibbs free energy minimization of $CF_3I$ was calculated to explain the decomposition mechanism.

      • KCI등재

        Overexpression of TTRAP inhibits cell growth and induces apoptosis in osteosarcoma cells

        ( Cai Hong Zhou ),( Qi Shen ),( Jin Glun Xue ),( Chao Neng Ji ),( Jin Zhong Chen ) 생화학분자생물학회(구 한국생화학분자생물학회) 2013 BMB Reports Vol.46 No.2

        TTRAP is a multi-functional protein that is involved in multiple aspects of cellular functions including cell proliferation, apoptosis and the repair of DNA damage. Here, we demonstrated that the lentivirus-mediated overexpression of TTRAP significantly inhibited cell growth and induced apoptosis in osteosarcoma cells. The ectopic TTRAP suppressed the growth and colony formation capacity of two osteosarcoma cell lines, U2OS and Saos-2. Cell apoptosis was induced in U2OS cells and the cell cycle was arrested at G2/M phase in Saos-2 cells. Exogenous expression of TTRAP in serum-starved U2OS and Saos-2 cells induced an increase in caspase-3/-7 activity and a decrease in cyclin B1 expression. In comparison with wild-type TTRAP, mutations in the 5`-tyrosyl-DNA phosphodiesterase activity of TTRAP, in particular TTRAPE152A, showed decreased inhibitory activity on cell growth. These results may aid in clarifying the physiological functions of TTRAP, especially its roles in the regulation of cell growth and tumorigenesis. [BMB Reports 2013; 46(2): 113-118].

      • KCI등재

        Paint Removal of Airplane & Water Jet Application

        Xue, Sheng-Xiong,Chen, Zheng-Wen,Ren, Qi-Le,Su, Ji-Xin,Han, Cai-Hong,Pang, lei Korean Society for Fluid machinery 2014 International journal of fluid machinery and syste Vol.7 No.3

        The paint removal and recoating are the very important process in airplane maintenance. The traditional technology is to use the chemical way corroding the paint with paint remover. For changing the defects, corrosion & pollution & manual working, of the traditional technology, the physical process which removes the paint of airplane with 250MPa/250kW ultra-high pressure rotary water jetting though the surface cleaner installed on the six axes robot is studied. The paint layer of airplane is very thin and close. The contradiction of water jetting paint removal is to remove the paint layer wholly and not damage the surface of airplane. In order to solve the contradiction, the best working condition must be reached through tests. The paint removal efficiency with ultra-high pressure and move speed of not damaged to the surface. The move speed of this test is about 2m/min, and the paint removal efficiency is about $30{\sim}40m^2/h$, and the paint removal active area is 85-90%. No-repeat and no-omit are the base requests of the robot program. The physical paint removal technology will be applied in airplane maintenance, and will face the safety detection of application permission.

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