Polydipsia as a Precursor of Manic Episode in Bipolar Affective Disorder Patients with Alcohol Use Disorder

Mehmet Emin Ceylan,Bariş Önen Ünsalver,Alper Evrensel 대한정신약물학회 2018 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.16 No.1

Bipolar affective disorder (BD) diagnosis and initiation of appropriate treatment are often delayed, and this is associated with poorer outcomes, such as rapid cycling or cognitive decline. Therefore, identifying certain warning signs of a probable successive episode during the inter-episode phase is important for early intervention. We present the retrospective data of three cases of BD. Our first case had a history of alcohol use disorder (AUD), where he drank in a dipsomaniac manner, and the other two cases had dipsomaniac alcohol use before their manic attacks, and none of them had any AUD after the mood episode was over. Two brothers also had hypertensive episodes during the manic attacks. None of the cases reported increased fluid intake when they were euthymic. We suggest that polydipsia in BD may be a warning sign of an upcoming manic episode, especially in those patients with AUD. Polydipsia in BD may be caused or facilitated by a combination of hyperdopaminergic activity, hypothalamic dysfunction, and dysregulated renin-angiotensin system. To be able to prevent new episodes, a patient’s drinking habits and change in fluid intake should be asked at every visit. Those patients with a history of alcohol abuse should especially be informed about polydipsia and manic episode association.

Failure load prediction of adhesively bonded GFRP composite joints using artificial neural networks

Bahadır Birecikli,Ömer Ali Karaman,Selahattin Bariş Çelebi,Aydın Turgut 대한기계학회 2020 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.34 No.11

There are different process parameters of bonding joints in the literature. The main objective of the paper was to investigate the effects of bonding angle, composite lay-up sequences and adherend thickness on failure load of adhesively bonded joints under tensile load. For this aim, the joint has four types of the bonding angles 30°, 45°, 60° and 75°. Composite materials have three different lay-up sequences and various thicknesses. The bonding angle, adherend thickness and composite lay-up sequences lead to an increase of the failure load. Moreover, artificial neural network that utilized Levenberg-Marquardt algorithm model was used to predict failure load of bonding joints. Mean square error was put into account to evaluate productivity of ANN estimation model. Experimental results have been consistent with the predicted results obtained with ANN for training, validation and testing data set at a rate of 0.998, 0.997 and 0.998 respectively.

Effect of fruit host on wing morphology in Drosophila suzukii (Diptera: Drosophilidae): A first view using geometric morphometrics

Ivana Pajač Živković,Darija LEMIC,Aleksandar MEŠIĆ,Božena BARIĆ,Rodrigo ÓRDENES,Hugo A. BENÍTEZ 한국곤충학회 2018 Entomological Research Vol.48 No.4

The invasive alien fruit pest Drosophila suzukii, (Matsumura 1931) causes economic loss in soft‐skinned fruit production across Europe. After its first detection in 2008, the species has successfully expanded to a wide geographic area and invaded new host plants in a relatively short period of time. The aim of the present study was to analyze the connection between food preferences as host specialization and the morphology of D. suzukii. Population morphological variation in wings was investigated in two different host fruits (grape and strawberry) in which economic damage has been recorded. The geometric morphometric results revealed two noticeable wing shape morphotypes in D. suzukii (i.e. vein configuration) between the grape and strawberry fruits. Flies reared in grapes had wider wings, whereas flies grown in strawberries had more narrow wings. These differences in morphotype could be explained by the effects of wing aerodynamics, which affect the strength of the wings in flight. This, in turn, can lead to better dispersion within the associated fruit host. These results confirm that this extremely invasive species, found worldwide, is successful at spreading in part because of its potential to adapt rapidly under different rearing conditions. Therefore, adaptive variations in the wing shape of D. suzukii can be used to differentiate populations based on food preference (e.g. soft fruits) and can serve as an additional tool for detecting different bioecological types of D. suzukii.

Heat recovery optimization of a shell and tube bundle heat exchanger with continuous helical baffles for air ventilation systems

Bari Md Ashfaqul,Münsch Manuel,Schöneberger Bastian,Schlagbauer Bernhard,Tiu Andrea Alina,WIERSCHEMANDREAS 대한설비공학회 2024 International Journal of Air-Conditioning and Refr Vol.32 No.1

We report a numerical evaluation of the impact of continuous helical baffle on the heat recovery efficiency of counterflow tube bundle heat exchangers. The baffle inclination angle has been varied from to . Since the fluid flows over the tube bundle at an angle due to helical flow inside the shell, the heat exchanger operates in cross counter mode. Fluent simulations with the k- transition shear stress transport turbulence model have been performed to investigate the thermal-hydraulic parameters of the system in terms of heat recovery efficiency, pressure loss, and overall heat transfer rate. Outside air temperature has been varied to mimic cold and warm weather. Pressure loss has been constrained to be less than 250 Pa, conforming to EU guidelines for energy labeling of residential ventilation units. At the maximum volume flow rate of 40 m /h, the device performed with over heat recovery efficiency for the considered temperature difference. Continuous helical baffles helped to improve convective heat transfer by reducing cross flow area and increasing velocity. Smaller angles result in greater pressure loss while having no discernible effect on heat recovery efficiency for the considered geometry. The analysis demonstrates the potential of a compact counterflowing recuperative heat exchanger with continuous helical baffles for decentralized ventilation systems and serves as a basis for further optimization.

Hydrodynamics of single-deadrise hulls and their catamaran configurations

Bari, Ghazi S.,Matveev, Konstantin I. The Society of Naval Architects of Korea 2017 International Journal of Naval Architecture and Oc Vol.9 No.3

Asymmetric planing hulls are often used on high-speed catamarans. In this study, a linearized potential-flow method is applied for modeling steady hydrodynamics of single asymmetric hulls and their catamaran setups. Numerical results are validated with available experimental data and empirical correlations. Parametric calculation results are presented for the lift coefficient and the center of pressure for variable hull geometry, spacings, and speed regimes. The lift coefficient is found to increase at smaller hull spacings and decrease at higher Froude numbers and higher deadrise angles.

Association between Taql polymorphism of vitamin D receptor gene and vertical growth of the mandible: A cross-sectional study

Baris Can Telatar,Gul Yildiz Telatar,Faruk Saydam 대한치과교정학회 2023 대한치과교정학회지 Vol.53 No.5

Objective: To determine whether the gonial angle on digital panoramic radiographs is associated with vitamin D receptor (VDR) Taql polymorphism. Methods: Genomic DNA samples were collected from the buccal mucosa of patients aged 26–43 years. TaqMan assay for single nucleotide polymorphism genotyping was used to detect the genotype of Taql polymorphism. The gonial angle was measured bilaterally on panoramic radiography. The normal gonial angle was fixed as 121.8°, and it represented the cutoff value for the high gonial angle (HGA) and low gonial angle (LGA) groups. Various genetic models were analyzed, namely dominant (homozygous [AA] vs. heterozygous [AG] + polymorphic [GG]), recessive (AA + AG vs. GG), and additive (AA + GG vs. AG), using the chi-squared test. Results: The reliability of the gonial angle measurement was analyzed using a random sample (26%) of the tests, with the intra-examiner correlation showing an intra-class correlation coefficient of 0.99. The frequencies of the AA, AG, and GG genotypes of rs731236 polymorphism were 40.5%, 41.9%, and 17.6% in the HGA group and 21.8%, 51.0%, and 27.2% in the LGA group, respectively (P = 0.042). A statistically significant difference was observed in the allele frequencies between the two groups (P = 0.011). Moreover, a significant correlation was observed in the dominant genetic model. Conclusions: Taql polymorphism in the VDR gene plays a critical role in the vertical growth of the mandible and decreased gonial angle.

Survey on Nucleotide Encoding Techniques and SVM Kernel Design for Human Splice Site Prediction

Bari, A.T.M. Golam,Reaz, Mst. Rokeya,Choi, Ho-Jin,Jeong, Byeong-Soo Korean Society for Bioinformatics 2012 Interdisciplinary Bio Central (IBC) Vol.4 No.4

Splice site prediction in DNA sequence is a basic search problem for finding exon/intron and intron/exon boundaries. Removing introns and then joining the exons together forms the mRNA sequence. These sequences are the input of the translation process. It is a necessary step in the central dogma of molecular biology. The main task of splice site prediction is to find out the exact GT and AG ended sequences. Then it identifies the true and false GT and AG ended sequences among those candidate sequences. In this paper, we survey research works on splice site prediction based on support vector machine (SVM). The basic difference between these research works is nucleotide encoding technique and SVM kernel selection. Some methods encode the DNA sequence in a sparse way whereas others encode in a probabilistic manner. The encoded sequences serve as input of SVM. The task of SVM is to classify them using its learning model. The accuracy of classification largely depends on the proper kernel selection for sequence data as well as a selection of kernel parameter. We observe each encoding technique and classify them according to their similarity. Then we discuss about kernel and their parameter selection. Our survey paper provides a basic understanding of encoding approaches and proper kernel selection of SVM for splice site prediction.

The Impact of Different Anthropometric Measures on Sustained Normotension, White Coat Hypertension, Masked Hypertension, and Sustained Hypertension in Patients with Type 2 Diabetes

Baris Afsar 대한내분비학회 2013 Endocrinology and metabolism Vol.28 No.3

Background: Many studies have aimed to determine whether body mass index (BMI), waist circumference (WC), or waist to hip ratio (WHR) best predicts hypertension in diabetic patients, with conflicting results. However, no study has examined the specific relationship between these anthropometric parameters with sustained normotension (SNT), white coat hypertension (WCHT),masked hypertension (MHT), and sustained hypertension (SHT) based on office and ambulatory blood pressure (BP) measurements in these patients.Methods: Patients with newly diagnosed type 2 diabetes underwent the following procedures: history taking, measurements of anthropometric parameters, office and ambulatory BP measurements, physical examination, laboratory analysis, and random and 24-hour urine analysis.Results: In total, there were 65 dippers and 37 nondipper patients. None of the anthropometric parameters were different between the dippers and the nondippers. There were 25 patients with SNT, 32 with WCHT, seven with MHT, and 38 with SHT. A comparison of anthropometric parameters between these four groups of patients showed that WC (P=0.016) and WHR (P=0.015) were different among all groups. According to regression analysis, only BMI was independently related with MHT (odds ratio [OR],1.373, P=0.022), whereas only WC has been associated with SHT (OR, 1.321, P=0.041).Conclusion: Among anthropometric parameters, only WC and WHR were different in SNT, WCHT, MHT, and SHT in newly diagnosed patients with type 2 diabetes.

Investigation of water length effects on the modal behavior of a prototype arch dam using operational and analytical modal analyses

Baris Sevim,Alemdar Bayraktar,Ahmet Can Altunisik 국제구조공학회 2011 Structural Engineering and Mechanics, An Int'l Jou Vol.37 No.6

This study determines the water length effects on the modal behavior of a prototype arch dam using Operational and Analytical Modal Analyses. Achievement of this purpose involves construction of a prototype arch dam-reservoir-foundation model under laboratory conditions. In the model, reservoir length was taken to be as much as three times the dam height. To determine the experimental dynamic characteristics of the arch dam using Operational Modal Analysis, ambient vibration tests were implemented for empty reservoir and three different reservoir water lengths. In the ambient vibration tests,the dam was vibrated by natural excitations provided from small impact effects and the response signals were measured using sensitive accelerometers. Operational Modal Analysis software process signals collected from the ambient vibration tests, and Enhanced Frequency Domain Decomposition and Stochastic Subspace Identification techniques estimated modal parameters of the dams. To validate the experimental results, 3D finite element model of the prototype arch dam was modeled by ANSYS software for empty reservoir and three different reservoir water lengths, and dynamic characteristics of each model were determined analytically. At the end of the study, experimentally and analytically identified dynamic characteristics compared to each other. Also, changes on the natural frequencies along to water length are plotted as graphs. Results suggest that reservoir water complicates the modal behavior of the arch dam significantly.

Suppressed Induction of Proinflammatory Cytokines by a Unique Metabolite Produced by Vibrio cholerae O1 El Tor Biotype in Cultured Host Cells

Bari, W.,Song, Y.-J.,Yoon, S.S. AMERICAN SOCIETY FOR MICROBIOLOGY 2011 Infection and immunity Vol.79 No.8