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Kefir 및 Yoghurt 에서 분리된 Lactobacillus spp. 와 Non - starter 균주에 의한 돌연변이억제(항암) 활성
윤영호,백영진,허철성,조중근 한국축산학회 1999 한국축산학회지 Vol.41 No.1
The antimutagenic activities of Lactobacillus spp. isolated from European kefir and yoghurt and those of non starter Lactobacillus and Bifidobaterium strains against 2-Nitrofluorene were studied by Ames test utilizing Salmonella typhimurium TA 98 to investigate probiotic effects of the strains. The optimal concentration of mutagen 2-nitrofluorene to produce 3,000 revertant colonies per plate turned out to be 10 ㎍/plate. Thirty six strains out of forty Lactobacillus spp. strains isolated from European kefir and yoghurt revealed antimutagenic activity and L. plantarum CU 722 showed the strongest antimutagenic activity of 50.34%. The antimutagenicity of non starter Lactobacillus and Brfidobacterium strains resulted in average 15% and 20% of mutation inhibition rate respectively. The effect of S-9 mix addition on the antimutagenicity rate against 2-Nitrofluorene was species and strain dependent.