구강편평상피암종에서 Aurora-2 kinase 발현에 대한 면역조직화학적 연구

한세진,김세웅,김경욱,Han, Se-Jin,Kim, Se-Woong,Kim, Kyung-Wook 대한악안면성형재건외과학회 2010 Maxillofacial Plastic Reconstructive Surgery Vol.32 No.2

Aurora kinases represent a novel family of serine/threonine kinases crucial for cell cycle control. Aurora-2 kinase is mainly involved in centrosome function, mitotic entry, and spindle assembly. Aurora-2 kinase overexpression causes centrosome amplification and the formation of multipolar mitotic spindles, which leads to tumor aneuploidy and so it has been found to play an important role in tumorigenicity in many cancers such as colorectal cancer, breast cancer and cervical cancer. Hence, the goal of this study is to identify the correlation of clinicopathlogical factors and overexpression of Aurora-2 kinase in oral squamous cell carcinoma. We studied the immunohistochemical staining of Aurora-2 kinase in 20 specimens of 20 patients with oral squamous cell carcinoma and the relationships between Aurora-2 kinase over expression and each of the clinico-pathological parameters were analyzed by Pearson correlation analysis. Statistical significance was set at P < 0.05. The results were as follows. 1. In the immunohistochemical study of poorly differentiated and invasive oral squamous cell carcinoma, the high level staining of Aurora-2 kinase was observed. 2. The correlation between immunohistochemical Aurora-2 kinase expression and histopathological differentiation of specimens was significant. These findings suggest that overexpression of Aurora-2 kinase may play a important role in carcinogenesis of oral squamous cell carcinoma.

전자상거래 지급결제의 핀테크 활성화를 위한 보안 및 법제도적 과제

한세진,Han, Se Jin 한국융합보안학회 2015 융합보안 논문지 Vol.15 No.2

정보통신의 발전과 금융서비스의 첨단화로 전자적 방식의 지급수단이 증가하고 혁신기술을 보유한 IT비금융권의 지급결제 참여가 활발해지고 있다. 시대적 요구에 부합하기 위해 정부에서도 최근 지급결제 간소화와 비금융기관 진출 여건 마련 정책을 발표한 바 있다. 그러나 전자금융 침해사고 빈도가 높은 국내 환경에서 안전성 담보가 없는 간소화 정책과 무분별한 비금융기관의 참여 확대는 보안과 책임문제에 있어 많은 문제점을 내포하고 있다. 당국에서는 비금융 참여기관의 요건을 강화하는 등의 조치를 마련하고 있으나, 강제성에 있어 민간차원의 자율에 맡기고 있는 실정이다. 본 연구는 정부의 전자상거래 규제완화 정책에 부응하여 지급결제시스템의 핀테크 활성화를 유도하기 위한 문제점과 해결방안을 검토해 보려는 것이다. 이를 위해 기존 지급결제서비스에 혁신기술을 접목함에 있어 발생할 수 있는 안전성 문제와 비금융회사의 법적 지위에 따른 책임 문제 등을 짚어보고 바람직한 법제 개선 방향을 제안하고자 한다. While information and communication develop, the Electronic commerce payment system is progressing. Recently, a government established the electronic commerce activation policy which simplified a payment Through this policy, the information which the financial company monopolizes can be fused with the other industry and create the popularization use of the electronic payment service and value added services. But on the other hand, the concern for the security is very high, Accordingly, the finnancial institute take a restriction of the requirements for the participation company according to the financial scale, this policy is led by the private institue, rather making a participation of fin tech venture difficulty. This paper tries to deal with the technical and legal problems for the activation of electronic payment system and fin tech. So I will examine the security matter that follows in grifting the innovation technology onto the existing payment service and propose a desirable way to improve the current legislation.

해외파병 구강악안면외과 전문의의 역할: 증례보고

한세진,Han, Se Jin 대한악안면성형재건외과학회 2013 Maxillofacial Plastic Reconstructive Surgery Vol.35 No.2

After the Iraq war, the Korean government established an Iraq Peace and Reconstruction Division, 'Zaytun'. Zaytun division has been dispatched in northern Iraq, since August 3, 2004. As one of our missions, 'Zaytun Hospital' was built to support the demand for the insufficient medical facilities and supplies in Iraq, which was opened on November 27, 2004. Zaytun Hospital, equipped with modern operation room and general ward, has been composed of 12 clinical departments. Although we had many problems, such as difficulty of communication with Iraqis, connection with medical facilities of Iraq and risk of terrorism, we overcame these difficulties and were able to achieve our missions successfully. I wish that our special experience in Iraq are will be the guideline to other oral and maxillofacial surgeons, who want to help those individual in unfortunate areas such as Iraq.

정신지체장애환자에서 Computer-Guided Surgery를 이용한 임플란트 식립 및 즉시 보철물 장착: 증례보고

한세진(Se-Jin Han) 대한턱관절교합학회 2014 구강회복응용과학지 Vol.30 No.3

악교정 수술과 함께하는 mandibular angle management

한세진(Se-Jin Han) 대한치과의사협회 2012 대한치과의사협회지 Vol.50 No.11

Orthognathic surgery(2-jaw or 1-jaw surgery) is very famous one of cosmetic techniques. However, primary purpose of orthognathic surgery is to improve the occlusion of jaw and secondary purpose is to improve the esthetic result. Unfortunately, many patients don’t only confuse often primary and secondary purpose of orthognathic surgery but they think the esthetic result is more important than the occlusion. Therefore, oral and maxillofacial surgeon has to fully understand cosmetic needs of patient and reflect that in the treatment plan. Patients with prominent mandibular angle want to have the narrower face of so called ‘V-line’ shape. Various techniques like the angle shaving, ostectomy of the lateral cortex around the mandibular angle and masseter musclectomy can be used for improving the mandibular angle hypertrophy. These techniques also can be applied in orthognathic surgery at the same time. We operated patients of orthognathic surgery, especially, with wide lower face and post-operative results were satisfactory in all cases. So, we propose mandibular angle management for improving the esthetic result of orthognathic surgery.

「申さる」에 관한 사적(史的) 고찰(考察) -중고(中古),중세(中世)의 물어(物語)를 중심으로-

한세진 ( Se Jin Han ) 한국일어일문학회 2015 日語日文學硏究 Vol.92 No.1

Mousu in a modern language is strongly known in standard as the honorific word but results of researches have been continually announced that it also has the meanings of main operation and operation object. Further, "Mousareru" is treated as a respect to the subject of the movement as well. This paper relates to the usage of respect of the subject of the movement of the modern word "Mousareu" and analyzes around the 233 examples of situations and subjects of the usage for "Mousaru" that has been extracted from 7 types of "Monogatari" that was classic in the Heian-Period and the Middle Ages where the first usage example of "Mousaru" appeared. The result of discussion is as follows. "Mousaru" that was used in "Monogatari" of the Heian-Period and the Middle Ages have been showing an overwhelming figure of 82% and 91% respectfully to the determining usage that proves where "Mousaru" pays respect for both the action object and the subject of the movement. However, similar to the modern word, an example that can be determined as a respect toward the subject of the movement was 12% and 8 % respectfully. Specifically, "Monogatari" of the Heian -Period where "Mousaru" is used in a situation where the subject of the movement is a listener and the upper person compared to the narrator was able to be determined as a respect for the subject of the movement. Additionally, when the subject, the action object is not clear or when the action object is an object, the "Mousaru" can be determined to be used as a respect for the subject of the movement. Lastly, the example of "Mousaru" used passively was 6% and 1% respectively. In such case, "Mousu" represents a respect for the audience as polite word "say" while the auxiliary verb "Ru" is considered to have a passive meaning.

「お~あ(や)る」考 : 虎明本狂言を中心に

韓世眞(Han Se-Jin) 한국일본문화학회 2004 日本文化學報 Vol.0 No.22

인공위성을 이용한 전력설비 모니터링 기술

한세진(Se-Jin Han),김경열(Kyoung-Yul Kim),정주환(Ju-Hwan Jung),이강렬(Kang-Ryul Lee) 대한전기학회 2020 대한전기학회 학술대회 논문집 Vol.2020 No.7

반도체 칩 캡슐화 성형 공정에 있어서 와이어 스윕 및 패들 변형에 관한 연구

한세진(Se-Jin Han),허용정(Yong-Jeong Huh),이성철(Sung-Cheol Lee) Korean Society for Precision Engineering 2001 한국정밀공학회지 Vol.18 No.2

일본어학(日本語學),일본어교육학(日本語敎育學) 편(篇) : 天草本『平家物語』에 보이는 「~(ら)るる」의 존경용법(尊敬用法) -경의(敬意)의 대상(對象)과 경의도(敬意度)를 중심으로-

한세진 ( Han Se Jin ) 한국일어일문학회 2011 日語日文學硏究 Vol.77 No.1

本稿では、天草本『平家物語』においての尊敬の助動詞「~(ら)るる」の意味用法を依据本である覺一本『平家物語』と對照し、「~(ら)るる」が表わす敬意の對象と敬意度について考察した。その結果は、以下のとおりである。覺一本に比べて、天草本では「~(ら)るる」が多く使われていたことが明らかになった。特に天草本では「會話文」よりは「地の文」での增加が目立つことがわかった。まず、「~(ら)るる」が第一のグル―プに使われた場合、次のように整理することができる。「~(ら)るる」が第一のグル―プに使われた場合、「會話文」と「地の文」ともに同じ文脈で使われた他の敬語と同じレベルの敬意で用いられたと言える。次に、「~(ら)るる」が第二のグル―プに使われた場合は次のように整理することができる。「會話文」では、話者が上位者に對して敬意を表わすために「~(ら)るる」を使った例と對等な關係でお互いに尊敬を表わすために「~(ら)るる」を使った例が見えた。また、話者が自分より下位のグル―プに對して使った場合は、自分の品位を表わすために使うか、または、威壓的な態度を表わすために「~(ら)るる」が用いられた。なお、「地の文」では、主に第二のグル―プに屬する話題の人物に敬意を表わすために「~(ら)るる」が使われていた。しかし第一のグル―プの「~(ら)るる」が同じ文脈で使われた他の敬語と同じ敬意度をもって用いられたことについては『平家物語』の他の版本との對照も必要であり、同時代の他の文獻との對照硏究も必要であると思われる。これについては今後の課題にしたい。