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      • KCI등재

        담도내 종양전을 동반한 양측성 간암에서의 2단계 간절제술

        정화경(Hwa-Kyung Jung),이동식(Dong-Shik Lee),윤성수(Sung-Su Yun),김홍진(Hong-Jin Kim) 대한외과학회 2008 Annals of Surgical Treatment and Research(ASRT) Vol.74 No.2

        Curative hepatectomy is the most important prognostic factor for hepatic cancer, but also has a high rate of morbidity and mortality. Liver failure due to insufficient liver volume is the main cause of postoperative mortality. Preoperative portal vein embolization can induce hypertrophy of the remnant liver, and a two-stage hepatectomy, with or without portal vein embolization, could be used to treat patients with unresectable liver tumors. We report the case of a successful two-staged hepatectomy for bilateral hepatocellular carcinoma with tumor thrombi.

      • KCI등재

        성인에서 발생한 세프트리악손 가성담석증의 증례보고 및 임상적 고찰

        정화경 ( Hwa Kyung Jung ),이동식 ( Dong Shik Lee ) 대한소화기학회 2014 대한소화기학회지 Vol.63 No.6

        Although ceftriaxone can be used safely in most instances, it can sometimes induce biliary sludge or stone formation. Most of the patients remain asymptomatic and children are more susceptible to develop this condition, but adults can be affected as well. Because sludge or stones disappear after discontinuing ceftriaxone, this condition is referred to as ceftriaxone-associated pseudolithiasis. A 54-year-old woman was admitted to a local clinic for management of ileus. During admission, she had received ceftriaxone and metronidazole, and had been on nil per os for the past 6 days. She was then referred to our hospital for cholecystectomy due to persistent right upper quadrant pain. Although imaging studies showed gallbladder sludge, pseudolithiasis was suspected because of ceftriaxone administration history and prolonged fasting. After careful watch-and-wait, the condition resolved spontaneously after ceftriaxone discontinuation. Our clear understanding on ceftriaxone-associated gallbladderpseudolithiasis allowed us to avoid an unnecessary cholecystectomy. Herein, we report the case of a 54-year-old woman with ceftriaxone-associated gallbladder pseudolithiasis that was successfully managed by ceftriaxone discontinuation alone. (Korean J Gastroenterol 2014;63:378-381)

      • KCI등재

        부인과 악성종양 환자에서 복합 항암화학요법에 따른 세포독성에 대한 Amifostine 의 임상효과에 관한 연구

        이린화(Lynn Hwa Lee),지현준(Hyun Jun Jee),정화경(Hwa Kyung Jung),정유아(Yu A Jung),신정호(Jung Ho Shin),오희숙(Hee Suk Oh),박용균(Yong Kyun Park),허준용(Jun Young Hur),조수용(Soo Yong Chough),서호석(Ho Suk Saw) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.11

        N/A Objective : Amifostine (Ethyol(R)), an organic thiophosphate, has shown the ability to protect normal, but not neoplastic, tissues from the damaging effects of chemotherapy and radiotherapy in various kinds of cancers. This study was designed to determine ifostine could reduce the serious hematologic and nephrologic toxicities associated with cisplatin based combination chemotherapy in gynecologic cancer patients. Patients and Methods : Forty patients who received cisplatin-based combination chemotherapy were randomized into two groups. They received chemotherapy with or without pretreatment of amifostine before each course. The occurrence of hematologic and renal toxicities were evaluated. Stastical analysis was done by independent t-test and Chi-square test. Results : Hematologic toxicity was evaluated with nadir count of neutrophil and platelet. The nadir count of neutrophil was 2034.2±1199.20/μl in group with pretreatment using amifostine vs 1070.85±472.66/μl in control group (p<0.01). Platelet count was not statistically different. (p<0.16) Grade 3 neutropenia was observed in nine (45%) patients in pretreatment group vs four (20%) patients with control group (p<0.09). Grade 4 neutropenia occurred in one patient only in control group. Renal toxicity was evaluated by serum creatinine and creatinine clearance. Protracted serum creatinine elevation was not significant in both groups. (p<0.14) Reduction of creatinine clearance was less in patients with pretreatment (p<0.01). There were no significant side reactions in subjects using amifostine. Conclusion : Pretreatment with amifostine reduces the neutropenia and nephrotoxicity associated with cisplatin-based combination chemotherapy with gynecologic cancer patients.

      • KCI등재

        한국 성인 여성의 월경지수에 관한 연구

        지현준(Hyun Jun Jee),정화경(Hwa Kyung Jung),조수용(Soo Yong Chough),박용균(Yong Kyun Park),서호석(Ho Suk Saw),오민정(Min Jeong Oh),허준용(Jun Young Hur) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.10

        목적 : 우리나라 성인 여성의 월경양상과 월경과다 시 쉽게 이용할 수 있는 진단방법, 월경 과다에 대한 인식정도에 대하여 알아보고자 하였다. 대상 및 방법 : 초등학교 여교사 77명을 대상으로 정기 신체검사시 설문지를 통해 월경양상과 월경과다에 대한 인식정도를 조사하였고 그림표를 사용하여 월경지수를 계산하고 신체검사시 시행한 혈색소량을 조사 하였다. 월경지수와 혈색소량을 Spearman correlation test를 시행하여 상관관계를 알아보았다. 결과 : 조사 대상 여성들의 월경주기는 29.8일 (SD±5.1), 월경기간은 평균 5.6일 (SD±1.3)이었고, 월경지수는 평균 170 (SD±89.2)으로 12에서 411의 분포를 보였고, 혈색소량은 평균 12.3 g/dL 이었다. 월경지수와 혈색소량 간에는 통계적으로 유의하게 선형관계를 보였다 (r=-0.29, p=0.01). 혈색소량이 12 g/dL 이하로 빈혈이 있는 여성은 20명 (26%) 중 17명 (85%)과 월경지수가 200 이상으로 월경과다인 여성 26명 (34%) 중 25명 (96%)이 본인의 생리가 정상이라고 생각하고 있었다. 결론 : 월경과다나 이로 빈혈이 있는 여성들 중 많은 경우에서 심각성을 느끼지 못하고 있으므로 보다 간편하고 정확하게 여성 스스로가 월경과다를 의심하고 병원을 찾을 수 있게 하는 방법이 필요하고 그림표를 이용하여 스스로 작성하는 월경일지가 이를 위한 유용한 방법이 될 수 있다. Objective : This study was designed to evaluate the patterns of menstruation including menorrhagia using menstrual index, to find out correlations between patient`s own judgement and actual patterns of menstruation in Korean women, and to develop the menstrual diary using menstrual index as a screening of menstrual disorders. Methods : Seventy-seven women teachers of elementary school undergoing routine health screening test were asked to complete a pictorial blood loss assessment chart and a set of interview sheets regarding menstrual history and their subjective judgement on their amount of menstruation. Spearman correlation test was used to assess the correlation between menstrual index which was obtained from pictorial chart and serum hemoglobin concentration. Results : The mean menstrual intervals were 29.8 days (SD±5.1), the mean menstrual duration was 5.6 days (SD±1.3), the mean value of menstrual index was 170.3 (SD±89.2) which varied from 12 to 411, the mean serum hemoglobin concentration was 12.3 g/dL. Significant correlation was found between the serum hemoglobin concentration and the menstrual index (r=-0.29, p=0.01). Seventeen of 20 women who had anemia (serum hemoglobin concentration below 12.0 g/dL) and 25 of 26 women who had menorrhagia (menstrual index above 200) considered her menstruation as `normal`. Conclusion : Many women who have anemia due to menorrhagia are not aware of the serious consequences of menorrhagia. Writing a ‘menstrual diary` using menstrual index would be easier and more practical method in predicting menorrhagia.

      • KCI등재

        자궁내막에 발생한 투명세포암 1 예

        지현준(Hyun Jun Jee),정화경(Hwa Kyung Jung),조수용(Soo Yong Chough),박용균(Yong Kyun Park),서호석(Ho Suk Saw),오민정(Min Jeong Oh),허준용(Jun Young Hur) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.10

        Clear cell carcinoma of the endometrium is a relatively rare malignancy that is considered to be one of the most aggressive types of endometrial carcinoma. It is an infrequent variant sharing a common Mullerian origin, accounting for 1 to 5 percent of all endometrial cancers. Histologically, these tumors consists of hobnail cells which have translucent or slightly eosinophilic cytoplasm and protrude to lumen of gland. These tumors occur predominantly in postmenopausal women and carry a relatively unfavorable prognosis comparing with other histologic types of endometrial cancer. We experienced a case of clear cell carcinoma of endometrium in a 81-year old women and this case is presented with a brief review of the literaturs.

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