미숙아에서 발견된 태생기 회장-회장형 장중첩증 1예

이보영,김여향,황진복,김천수,이상락,권태찬,이희정,박우현,Lee, Bo Young,Kim, Yeo Hyang,Hwang, Jin Bok,Kim, Chun Soo,Lee, Sang Lak,Kwon, Tae Chan,Lee, Hee Jung,Park, Woo Hyun 대한소아소화기영양학회 2005 Pediatric gastroenterology, hepatology & nutrition Vol.8 No.2

미숙아에서 드물기는 하나 심한 복부 팽만과 담즙이 섞인 구토, 혈변 등의 증상이 비교적 일찍 초래되는 경우 장중첩증을 감별 진단으로 고려하여야 한다. 저자들은 극소 저출생 체중 미숙아에서 괴사성 장염과 유사한 증상을 보였으나 생후 11일경에 수술로 진단된 회장 폐쇄를 동반한 태생기 회장-회장형 장중첩증 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Intussusception in a preterm neonate is a very rare disorder. We experienced a case of intrauterine intussusception presented with symptoms of the small bowel obstruction in a preterm infant whose gestational age was $28^{+2}$ weeks. Urgent ultrasonography of abdomen revealed no definite intussuscepted segment. At emergent surgery performed on the 11th days of life under the diagnosis of distal small bowel obstruction, an ileo-ileal intussusception with distal ileal atresia without perforation was found.

보수용접기술 기초

이보영,Lee Bo-Young 대한용접접합학회 2005 대한용접·접합학회지 Vol.23 No.1

일개 대학병원에서 제한 항생제 전산 프로그램 운용에 따른 항생제 사용량 변화

이보영,김천수,류성열,권기영,임정근,임태진,민병우,류남희,차순도,Lee, Bo Young,Kim, Chun Soo,Ryu, Seong Yeol,Kwon, Ki Yung,Lim, Jung Geun,Lim, Tae Jin,Min, Byung Woo,Ryoo, Nam Hee,Cha, Soon Do 대한소아감염학회 2006 Pediatric Infection and Vaccine Vol.13 No.2

목 적 : 감염병 치료를 위해서 항생제의 적절한 선택은 필수적이며 잘못된 사용은 내성균주의 출현과 확산, 치료의 실패, 약물 부작용, 의료비 상승 등의 다양한 문제점을 초래한다. 저자들은 임상에서 특정 항생제의 사용을 제한하는 전산 프로그램의 운용이 항생제의 부적절한 사용을 억제하고 약제 사용량 감소에 도움이 되는지 알아보고자 본 연구를 시행하였다. 방 법 : 항생제관리위원회의 의결로 내성의 우려가 있는 고가의 항생제와 과거에 부적절한 사용 경향을 보였던 약제 등 총 7계열의 16개 품목을 제한 항생제로 선정하였다. 입원환자를 대상으로 제한 항생제 관리용 전산 프로그램 운용 후인 2004년과 2005년 5~7월(연구군) 및 운용 전인 2002년과 2003년 동일기간(대조군)에 처방된 항생제의 사용 내역을 후향적으로 조사하였다. 항생제 사용량 비교를 위한 지표는 1일당 재원환자 100명당 항생제 사용자수(명)로 하였으며 일별 항생제 사용 환자수를 조사한 후 재원환자 100명당 사용자수를 산정하였으며, 계열별로 양군간 비교를 시도하였다. 결 과 : 1일 재원 환자수는 대조군($823.5{\pm}37.1$명)이 연구군($809.2{\pm}39.3$명)보다 많았으며(P<0.001), 1일 퇴원 환자수(연구군 : $81.2{\pm}16.0$명 vs. 대조군 : $81.5{\pm}16.9$명)와 재원일수(연구군 : $9.9{\pm}1.6$ vs. 대조군 : $10.0{\pm}2.1$)는 양군간 비슷하였다. 1일당 재원환자 100명당 항생제 사용자수(연구군 vs. 대조군)는 항진균제($0.6{\pm}0.3$명 vs. $0.7{\pm}0.4$명)와 glycopeptides ($4.1{\pm}0.7$명 vs. $4.2{\pm}0.6$명)는 양군간 비슷하였고, carbapenems($1.9{\pm}0.5$명 vs. $0.9{\pm}0.3$명)과 piperacillin-tazobactam($0.7{\pm}0.3$명 vs. $0.3{\pm}0.2$명), quinolones ($2.2{\pm}0.6$명 vs. $1.6{\pm}0.5$명)은 연구군에서 더 많았으며(P<0.001), 고가의 광범위 cephalosporins($1.3{\pm}0.4$명 vs. $1.6{\pm}0.3$명)와 부적절한 사용 경향을 보였던 약제($1.1{\pm}0.5$명 vs. $6.0{\pm}1.4$명)는 연구군에서 유의하게 감소하였다(P<0.001). 결 론 : 항생제 사용을 제한하는 전산 프로그램의 운용은 임상자료 분석에서 부적절한 사용 경향을 가진 항생제의 사용을 줄이는데 효과적이나 내성균 치료제나 고가 약제의 사용량 감소를 위해서는 미흡한 조치이며 이에 대한 추가적인 대책이 필요하다. Purpose : Appropriate use of antimicrobials is an essential factor to treat infectious diseases and prevent acquisition of antimicrobial resistant pathogens. This study was undertaken to search that application of computerized management program for restriction of antimicrobials use in a hospital is helpful to decrease antimicrobial use density. Methods : Antibiotics utilization committee decided to restrict the use of 16 antimicrobials(14 expensive drugs having fear of drug resistance by pathogens and additional two drugs with inappropriate using tendency). Retrospective evaluation of antimicrobial user numbers between May and July of 2004 and 2005(study group) was conducted to compare with previous use density during same period of 2002 and 2003(control group). Results : Inpatients number of control group($823.5{\pm}37.1$ persons) was more than study group($809.2{\pm}39.3$ persons, P<0.001), but, outpatients number and hospitalized duration were equal in two groups. Antimicrobial user number/100 inpatients per day of glycopeptides and antifungal agents was equal in two groups, and study group was significantly higher density than control group in the use of carbapenems, piperacillin-tazobactam and quinolones(P<0.001). But study group was significantly lower density than control group in the use of drugs with inappropriately using tendency and expensive cephalosporins having broad antimicrobial spectrum(P<0.001). Conclusion : Application of computerized management program for restriction of antimicrobials use in a hospital is effective to decrease the use density of antimicrobials with inappropriately using tendency, but it is an insufficient measures for the restricted use of other antimicrobials on the whole.

연구논문 - Properties of Welded Joints - : 용접부의 기계적 성질에 미치는 Ni 과 Mn 의 복합 효과

이보영,정재필 ( Bo Young Lee,Jae Pil Jung ) 대한금속재료학회 ( 구 대한금속학회 ) 1988 재료강도 심포지엄 Vol.- No.-

전이성 췌장암의 치료

이보영,우상명,Bo Young Lee,Sang Myung Woo 대한소화기암연구학회 2018 Journal of digestive cancer reports Vol.6 No.2

Pancreatic ductal adenocarcinoma is a dismal prognosis and 5^th leading cause of cancer related death in Korea. A large proportion of patients are diagnosed at advanced or metastatic stage. Therefore systemic chemotherapy has become the mainstay of treatment for pancreatic cancer. For most patients advanced or metastatic pancreatic cancer that has a good Eastern Cooperative Oncology Group performance status (ECOG PS) 0 or 1, we can recommend for FOLFIRINOX (leucovorin, 5-fluorouracil [5-FU], irinotecan and oxaliplatin) and gemcitabine plus nanoparticle albumin-bound paclitaxel (nab-paclitaxel). Currently, steps towards improved therapeutic efficacy of palliative chemotherapy have been made by introducing these regimens. For patients with an ECOG PS of 2, gemcitabine monotherapy or S1 alone is recommended. The second-line therapy for patients initially treated with gemcitabine-based chemotherapy includes provide FOLFOX (leucovorin, 5-FU, and oxaliplatin), capecitabine plus oxaliplatin, and 5-FU plus liposomal irinotecan. The gemcitabine-based chemotherapy is a reasonable choice for patients treated with FOLFIRINOX. Currently, studies on selecting patients for biomarkers related to molecular biologic features of tumors are underway for the realization of precise medicine, and the development and verification of preclinical models for the development of new therapeutic agents are being carried out continuously.

사향(麝香)이 생쥐의 뇌손상(腦損傷)에 미치는 영향(影響)

이보영,강석봉,Lee, Bo-Young,Kang, Seok-Bong 대한한의학회 1995 대한한의학회지 Vol.16 No.2

The studies were investigated in the coma time and the survival time induced by KCN, the duration of breathing after decapitation, the survival time following ligation of both common carotid arteries and the survival time after it is treated for normobaric bypoxia with a nitrogen gas, a carbon dioxide gas or a vaccum in mice. The results were as follows: 1. In histotoxic anoxia, Moschus(0.4mg/kg, p.o) demonstrated a protective effect on coma induced by a sublethal dose of KCN(1.8mg/kg, i.v.) in mice. 2. Mice subjected to a lethal dose of KCN(3.0mg/kg, i.v.) did not die by administration of Moschus. 3. Moschus was significantly extended the duration of breathing after decapitation in mice. 4. Moschus showed a significant extension of survival time in mice following ligation of both common carotid arteries. 5. In the normobaric hypoxia with a nitrogen gas, Moschus showed a significant extension of survival time in mice. 6. In the normobaric hypoxia with a carbon dioxide gas, Moschus showed a significant shortness of survival time in mice. 7. In the normobaric hypoxia with a vaccum, Moschus showed a significant extension of survival time in mice. From the above results, it is suggested that Moschus demonstrated protective effects on the brain damages induced by cerebral anoxia.

자금세탁방지법제에 대한 형법적 검토

이보영(Lee, Bo-Young) 한국형사법학회 2009 刑事法硏究 Vol.21 No.1

money laundering is the process by which criminal funds are turned in to clean money which appears to have been obtained from a legitimate source. The process is commonly used by drug traffickers, terrorists and organised crime syndicates. The Process involves three key stages ① placement of the proceeds of crime into the financial system ② layering to separate the money it's origins ③ integration, where the funds are integrated back into the economy to appear legitimate in order that the launderer can use the funds. The current Anti-Money Laundering System in Korea is severely below the 40 recommendations made by FATF(Financial Action Task Force on Money Laundering), the international standard in the area. Although the recommendations by FATF are not legally binding, the recent warnings given by FATF of measures to be taken with respect to countries that do not or insufficiently comply with the FATF Recommendation calls for a more concrete analysis of the content and the problems in reformation of the policies in preventing money laundering in South Korea. The contents of this paper is as follows. ① Introduction ② Concept of money laundering ③ Money laundering regulations ④ Current statue and problem in Korean money laundering regulations. ⑤ A criminal Examination on Regulations of money laundering ⑥ Conclusion

형벌의 의미와 정당성 -언제나 형벌은 필요한가?-

이보영 ( Bo Young Lee ),송경석 ( Keyong Seog Song ) 법조협회 2011 法曹 Vol.60 No.5

This article mainly explores next some questions: (i) should not the purpose and meaning of criminal penalty place not only on retribution and precaution, but also on governing of the conflict? (ii) Does argument regarding justification of criminal punishment under the purpose of the criminal penalty needed? (iii) How are the discussion about the justification of criminal punishment?, and (iv) Do we always need the criminal penalty. The vital point of this work as follows: First, regarding the issue on what basis of the criminal punishment imposed is may be answered with it lies in that the criminal punishment may be assigned via the state, the justification of the law, protection of community, etc. If criminal penalty has lack in the justification, it is better that criminal punishment is less being applied. Second, concerning the questions that the criminal punishment should be unconditionally put it on to defendant may be answered with the state criminal punishment power is subject to the principle of responsibility and it should restrictively be used within the limitations. Third, about the inquiry that always the criminal punishment is necessary may be response by applying the notion that the necessity of criminal penalty required by supplemental and effectiveness of the criminal penalty as a precondition. That is to say, to suppress the harmful act and behavior in the society it must be minimal methods or tools that are necessary and the criminal penalty which are lacks in effectiveness are unnecessary as a criminal penalty. Fourth, is the purpose of criminal punishment only retribution and precaution? An attempt to resolve the long-pending trouble of the nature of criminal penalty shall be put in restored or restitution judicature by focusing the managing the conflicts. Ultimately, the criminal penalty must be required the justification, and if not, it is better that the power of imposition of criminal punishment shall be minimally applied. Moreover, we should be out from the traditional perspective of the criminal penalty and exert to rehabilitate the damages of the victim and require adjusting conflict between victim and perpetrator. Note that the states` power of imposition of the criminal penalty may find the justification in that the power may only use within the limitation of ``rule of law`` principle and if it is applied beyond the liberalism with the dignity of human beings it deviate from the modern general idea.

수형자들을 위한 교정 프로그램과 심리검사의 타당성

이보영(Lee Bo-Young),홍기원(Hong Ki-Won) 숭실대학교 법학연구소 2012 法學論叢 Vol.27 No.-

Punishment has changed across time and cultures. It is likely that some of the current trends in punishment will be rejected in a few years time. Punishment is a constantly evolving aspect of society and is linked to thoughts about safety, the effectiveness of the criminal justice system and emotional responses to victimization. The unique physical and social environment in prison does seem particularly prone to causing stress. And prisoners are individuals, and vary in the stressors they experience and how they try to cope with these. The prison environment also seems to limit the means by which prisoners can cope with stress. We have to heed on some populations of prisoners who suffer particular stressors: life-sentence prisoners and prisoners who are mothers. The questions of rehabilitation of offenders, so called 'What Works' debate, is whether treatment is effective. A couple of examples of the programmes were suggested with the related evidence. And the results are the rehabilitation of offenders may be successful for certain individuals and under certain conditions as "Think First" or "ART"(Aggression Replacement Training). PCL-R test for determining whether a offender poses a risk of further violence if released. "Lifer" like Robert Dixon took a test to determine whether he was a psychopath for a parole hearing. This test has incredible power in the American criminal justice system. Many psychologists believe that psychopaths are so devoid of normal human emotion, so cold and remorseless and impulsive, that they are bound, almost by their very nature, to do harm and violence. But this assumptions could lead error prone decision like Robert Dixons case. Predictive power of psychological test is assumed on the determination of nature rather than nurture. Recently, more studies support of environmental power compared to biological characteristics. Hence more studies are needed to answer for the right individuals targeted for the right programmes and tests.

성폭력범죄자의 성충동약물 치료에 관한 법률의 정당성 및 실효성 검토

이보영 ( Lee Bo-young ),홍기원 ( Hong Ki-won ) 한국외국어대학교 법학연구소 2011 외법논집 Vol.35 No.4

Throughout history, surgical castration has been used to punish sex offenders. In the developed world, the practice of removing the testes was considered a viable treatment that is able to prevent recidivism in offenders who commit crimes of sexual nature. With the advent of medicine in the seventies of the last century, drugs that can produce the same, if not better, effect were discovered. This prompted most of the countries practicing castration on sex offenders to abandon the surgical treatment and continue using chemical castration to achieve the same goals instead. In 1996, the California legislative assembly intensified the competition in what seems to be an ever increasing race to enact the most draconian penalties for child molestation. Out of a desire to punish child molesters and to take a tough stance on crime, California’s legislative assembly amended section 645 of the California Penal Code to mandate chemical castration of certain recidivist child molesters upon parole. The statute provides that commencing January 1, 1997, the State of California will chemically castrate all parolees who have more than one conviction for molesting a child under thirteen years of age. Across the nation, the subject of the violent repeat sexual offender elicits strong emotional reaction from the public, which in turn motivates legislators to increase criminal justice sanctions for sexual offense perpetrators. Society’s increasing intolerance of individuals who commit crimes against children is evidenced by the enactment of the so-called “Megan’s Laws” and “Sexually Violent Predator Acts.” Section 645 is another step in an attempt to satiate the public’s desire for retribution. Chemical castration may indeed be an appropriate treatment measure for some offenders, but a question remains concerning whether it is appropriate for a legislative body to make this determination. The medical community does not recognize one standardized treatment or therapy program as appropriate for all child molesters. Therefore, it is troubling that the California legislative assembly has prescribed chemical castration as the mandated course of treatment for all child molesters without providing for any medical consultation on an offender-by-offender basis. Surgically removing the testes is an invasive and irreversible procedure that permanently changes the human body. Aside of diminishing sexual desire and potency, the procedure completely eliminates the ability for procreation. Surgical castration can also lead to adverse side-effects that are both of physical and psychological nature. Taking hormonal drugs that are easily available for purchase, however, restores the sex drive and makes it possible for sex offenders to engage in sexual intercourse even though their testes are removed. This is not the case with chemical castration as testosterone can not reverse the effects of anti-androgyne drugs. Although research shows that surgical castration is a very effective method that significantly reduces recidivism in sex offenders, independent review studies have shown that the positive effects might not be based on genuine scientific evaluation. Today, there are conflicting opinions within the medical community whether the intervention does more to prevent sex offenders from re-offending than other available treatment. Therefore, surgical castration can not be considered as a reliable treatment for sex offenders. This raises the question whether the treatment can be considered legally permissible. It is also questionable if the procedure can pass the constitutionality test with regard to the prohibition of cruel, inhuman, or degrading treatment or punishment, the fundamental rights to marry and found a family as well as to human dignity and integrity. When these fundamental legal questions are combined with the advent of modern medicine and the possibility to reach the desired goal by alternative unobtrusive treatment, it becomes apparent that surgical castration is not only impermissible but also unnecessary. This research will be a deep impact in the area of criminal and constitutional law field.