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      • 미숙아의 제반사항 및 간호에 관한 임상적 고찰

        李君子 中央醫學社 1974 中央醫學 Vol.26 No.4

        This clinical study was done 85 premature infants among 803 new born babies delivered during three years from the January 1, 1971 to December 31, 1973 at the Department of Obstetrics and Gynecology of Inchon Provincial Hospital. The premature infants who weighed under 2500 gm were chosen as the subject ,of this study and as a result their related matters and considerations on clinical _nursing care were as follows. 1) The birth incidence of the premature infants was 10.6%. 2) The distinction of sex. in premature infants was 48 cases (56.5%) of female and 37 cases (43.5%) of male. 3) The birth weight of premature infants was 23 cases (27.0%) belong to the group of 2251-2500 gm which was the top, and the average birth weight was 1915.5 gm in male and 1898.4 gm in female, therefore their both average birth weight was 1907 gm. It showed that the male weighed more than, the female by 17.1 gin and as they weighed more their numbers increased. 4) The number-of the twins in. the premature infants was 14 cases (16.5%). 5) The birth length of premature infants was 48 cases (68.3%) were under 47 cm and the 7 cases (8.2%) were over 50 cm. 6) The gestation period of premature infants was 55 cases (64.7/) were under 37 weeks and 20 cases (23.5%) were over 40 weeks. 7) The mothers who gave birth to premature infants were from 26 to 30 years old and the number of them was topped by 30 cases (38.0%). 8) The mothers who had maternal diseases in the period of-pregnancy were 39 cases (49. 4%) and no problems or others were 40 cases (50.6%). Judging from what it revealed, toxemia was the greatest . in number by 15 cases (19.0%). 9) The parity of premature infants was the first babies were the greatest in number by 38 cases (44.7%'). It indicated that the higher in parity, the lower in number. 10) Monthly delivery number of premature infants was 28 cases (32.9%) topped in figure were born from March to May. 11) The delivery type of premature infants was .27 cases (31.88%) topped in number were extracted by vacuum. 12) The mothers who gave birth to, premature infants was 49 cases (62.0%) had not received prenatal care and 30 cases (38.00) had. 13) The dead of premature infants was 15 cases (17.7%).

      • SCIESCOPUSKCI등재

        Mouse 신장으로부터 Ornithine Decarboxylase의 정제

        이군자,조영동 한국생화학회 1992 BMB Reports Vol.25 No.5

        자성 mouse의 피하층에 testosterone을 투여하여 ornithine decarboxylase의 활성을 증가시킨 후, 신장으로부터 ornithine decarboxylase를 황산암모늄 분별침전, DEAE-sephacel chromatography, hydroxylapatite chromatography, pyridoxamine-5'-phosphate agarose affinity chromatography를 이용하여 분리 정제하였다. 이 효소의 분자량은 SDS-polyacrylamide gel electrophoresis, Sephacryl S-200 gel chromatography와 ornithine decarboxylase의 효소활성 억제제인 14C-DFMO 을 효소와 결합시켜 얻은 autoradiography를 이용하여 52,000 dalton인 동일한 subunit으로 구성된 dimer임을 알 수 있었다. 정제된 효소의 ornithine에 대한 K_(m) 값과 V_(max) 값은 각각 167㎛과 5 nmol CO_(2)/h로 나타났고, pyridoxal-5-phosphate에 대한 K_(m) 값과 V_(max) 값은 각각 0.142㎛과 2.4nmol CO_(2)/h로 나타났다. 효소의 최적 pH 는 7.0, 최적 온도는 37℃이었으며, 정제된 ornithine decarboxylase는 polyamines(putrescine, spermidine, spermine)에 의해 효소 활성이 영향을 받지 않았다. 본 실험에서는 ornithine decarboxylase의 분리과정 중에서 ornithine decarboxylase 활성을 안정화시키는 물질을 발견하였다. Ornithine decarbosylase (ODC) was purified to homogenity from testosterone treated mice kidney by ammonium sulfate fractionation, DEAE-Sephacel chromatography, hydroxylapatite chromatography, pyridoxamine-5-phosphate-agarose affinity chromatography. The specific activity of ODC was 14,000 U/㎎, and purification fold was 1,180. The enzyme has a Mr. of about 110,000 dalton and is a dimer of subunit Mr. 52,000. The K_(m), for L-ornithine was 167㎛ and for pyridoxamine phosphate, 142 nM. ODC has an optimum pH of 7.0 and optimum temperature of 37℃. The purified enzyme was not inhibited by polyamine (putrescine, spermidine and spermine). During purification process, ODC stabilizing material was found.

      • 최루가스(o-Chlorobenzylidene Malononitrile)가 흰쥐의 각막과 결막에 미치는 영향

        이군자 서울보건대학 1995 서울보건대학 부설 한국보건과학연구소 논문집 Vol.2 No.1

        Two groups of rats were exposed to the o-chlorobenzylidine malononitrile(CS) being used in the control of riots, and sacrificed to examine histological and histochemical changes of the cornea and conjunctiva. 1. In animals exposed to the CS gas (50mg/min./㎥) for 20min., reversible histological changes were observed in the cornea. Epithelial and endothelial Na,^(+) K^(+) -ATPase activity were reduced, wing cells of the epithelium were transformed to the squamous shape and mitotic activity occurred actively in the basal layer. 2. In animals exposed repeatedly to the CS gas (50mg/min./㎥) for 20min. once a day for 10 days, Na^(+), K^(+)-ATPase, Mg^(2+)-ATPase and alkaline phosphatase activities of the corneal epithelium and endothelium were reduced. And there was epithelial shrinkage, irregular basement membrane and irregularly arranged collagen fibers were also observed in the stroma. 3. In animals exposed to the CS gas (50mg/min./㎥) for 20min., reversible histological changes were observed in the conjunctiva. Mucin secreting activity of the goblet cells was reduced and lymphocytes, eosinophils were infiltrated. 4. In animals exposed repeatedly to the CS gas (50mg/min./㎥) for 20min. once a day for 10 days, irreversible changes were observed. Desquamation with oedema and shrinkage of the epithelial cells, and loss of some basement membrane were observed. Mucin secreting activity of the goblet cells was reduced and lymphocytes, eosinophils were infiltrated significantly. As a result when eyes are temporally exposed to the CS gas reversible degenerative changes, desquamation with oedema of the epithelium and infiltration are produced. And when eyes are repeatedly exposed to the CS gas histopathologic changes such as desquamation with oedema of the epithelium, infiltration, and reduced mucin secreting activity are occurred.

      • 신생아 집중치료실에서 퇴원한 환아 부모에게 전화상담한 내용과 간호중재에 대한 조사연구

        이군자 京畿專門大學 2000 京畿專門大學 論文集 Vol.- No.28

        The purpose of this study was to identity the current status of nursing intervention by telephone. A head nurse of the intensive care unit wrote down the content of interview with parents of newborn discharged from hospital from 7 a. m. to 3 p. m. during the period of February through December in 1999. The content of 150 telephone calls except incomplete record among 460 calls were analyzed into frequency of general characteristics, content and nursing intervention by 11 categories. The findings of this study were as follows; 1. The proportion of males to females, male patients(50.0%) female patients(50.0%) by the ratio of 1:1 and the most common age was 1-2 weeks. 2. The most common admission period was within 1 week. 3. The most common diagnosis during admission period was jaundice, premature. 4. The most frequent contents were physical symptoms and vital sign, a jaundice and diarrhea among physical symptoms, fever and respiratory difficulty among vital sign. 5. Nursing intervention through telephone was identified with order to confirmation, direction, education, inducement. 6. The most frequent nursing intervention by telephone was good condition in confirmation, diarrhea in direction, feeding amount in education, follow up care in inducement. These results suggest that telephone call intervention program should be established as afield of extended pediatric nursing role in health care delivery system for the newborn.

      • KCI등재

        운동프로그램이 중년비만여성의 체구성, 체력 및 지질대사에 미치는 효과

        이군자 한국간호과학회 2005 Journal of Korean Academy of Nursing Vol.35 No.8

        Purpose: This study was to examine the effects of an exercise program for middle-aged obese women. Method: The exercise program combined folk dance and resistance training. The subjects group consisted of 85 middle-aged obese women between 40 and 60 years of age. Three 8 week sessions consisted of a 55-80% maximum heart rate (MHR) exercise for 60-90 minutes a day and 3 times a week from March to November, 2004. Data was collected through a pre- and post-exercise test before and after each session. Data was collected with Inbody, dynamometer and blood. This data was analyzed by descriptive statistics, and a paired t-test with an SPSS/PC(10.0 version) program. Results: There were significant positive changes in body weight, body fat mass, body mass index, percent body fat, muscle strength, muscle endurance, flexibility, and balance quality, but no significant positive changes in skeletal mass, fat free mass, percent abdominal fat(waist-hip ratio), visceral fat area, agility, total cholesterol, high density lipoprotein cholesterol, or triglycerides. Conclusion: This study showed that an exercise program has partially positive effects for middle-aged obese women. The results of this study show that exercise at community health centers should continue for middle-aged obese women's health.

      • SCOPUSKCI등재

        운동프로그램이 성인여성의 체력, 심폐기능 및 생활만족도에 미치는 효과

        이군자 지역사회간호학회 2005 지역사회간호학회지 Vol.16 No.2

        The Effects of an Exercise Program on Physical Fitness, Cardiopulmonary for Adult Women Purpose : This study was to examine the effects of an exercise program on physicalfitness, cardiopulmonary function and lifesatisfaction for adult women. Method : Theexercise program combined dance and resistancetraining. The subject group consisted of 114 women aged between 33 and 60. Three 8-week sessions consisted of 55-80% HR max for 60-90 minutes a day and 3 times a week from March to November, 2004. Data were collected through pre- and post-exercise tests before and after each session. Data were collected with dynamometer, sphygmomamometer, spirometer and structured questionnaires. Data were analyzed employing descriptive statistics and paired t-test with SPSS/PC(10.0version) program. Results: There were significantly positive changes in muscle strength, flexibility, balance quality, forced vital capacity and life satisfaction, but no significantly positive change in agility and blood pressure. Conclusion : This study showed that an exercise program has partially positive effects for adult women. The result of this study suggest that there should be programs of continuous exercise at community health centers for adult women's health.

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