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트리암시놀론이 배양망막상피세포에서 생산된 혈관형성관련인자에 미치는 영향
이영창,윤태중,최광주,김대현,Young Chang Lee,Tae Jung Yoon,Gwang Ju Choi,Dae Hyun Kim 대한안과학회 2009 대한안과학회지 Vol.50 No.4
Purpose: To examine the effects of triamcinolone on angiogenesis related factors in cultured human retinal pigment epithelial cells Methods: Human retinal pigment epithelial cells were exposed to triamcinolone, cultured in a hypoxic environment, and expression and production of VEGF and PEDF were subsequently tested by RT-PCR and Western blot. Angiogenesis was measured via a tube formation assay using ECV 304 cells and with a migration assay using human dermal microvascular endothelial cells. Results: Expression and production of VEGF and PEDF were tested by RT-PCR and Western blot, respectively. VEGF abundance was reduced while that of PEDF was unchanged in triamcinolone exposed retinal pigment epithelial cells cultured in hypoxic environment compared with cells with no treatment in hypoxic environment (p<0.05). Tube formation and cell migration were reduced by triamcinolone (p<0.05). Conclusions: These results suggest that triamcinolone affects the secretion of angiogenesis-related factors and suppresses neovascularization. J Korean Ophthalmol Soc 2009;50(4):594-602
2-microphone method을 이용한 자동차용 내장재의 임피던스 측정 실험
金寬柱,尹泰重 弘益大學校 科學技術硏究所 2001 科學技術硏究論文集 Vol.12 No.-
Sound absorption and impedance are two important parameters in identifying porous materials' behavior. To reduce the interior noise of automobiles effectively, the above parameters should be known in detail. Impedance tube method with two microphones is performed to obtain the impedance of absorbing materials. By switching two microphones, more accurate impedance results are obtained. Flow resistivity, one of four Biot's parameters, is measured and by applying Delany-Bazley's law on the measurement results, impedance values are calculated. Impedance results from both the impedance tube method and flow resistivity with Delany-Bazley's law are compared with and show reasonable results in certain frequency bands. The computer simulation with SYSNOISE is also conducted to verify the impedance measurement results.