담관낭종의 임상적 고찰

설지영(Ji-Young Sul),손기섭(Ki-Sub Son) 대한외과학회 1992 Annals of Surgical Treatment and Research Vol.43 No.1

소장 및 대장을 침범한 복벽 유건종(Desmoid tumor) 1예

설지영(Ji Young Sul),노승무(Seung Moo Noh),서광선(Kwang Sun Suh) 대한외과학회 1993 Annals of Surgical Treatment and Research Vol.44 No.1

히르슈슈프룽병의 일차성 복강경 보조 Endorectal Pull-Through 술식의 임상적 고찰

박병순,설지영,Park, Byung-Soon,Sul, Ji-Young 대한소아외과학회 2013 소아외과 Vol.19 No.2

The application of laparoscopic techniques for the surgical management of Hirschsprung's disease is the recent trend. We described the surgical technique and postoperative long-term outcomes of the one-stage, laparoscopic-assiseted endorectal pull-through operation for Hirschsprung's disease. The technique uses three to four small abdominal ports. Laparoscopic mobilization of the sigmoid colon and rectum is performed and marginal artery-preserving colon pedicle is prepared. The rectal mobilization is performed using a transanal endorectal sleeve technique. The anastomosis is performed 0.5~1 cm above the dentate line. The age at surgery ranged from 6 days to 4 years. The average operative time was 144 minutes. Almost all of the patients passed stool and flatus within 36 hours of surgery. The average hospital stay after surgery was 6.5 days. Among 42 patients, 32 patients older than 3 years old were evaluated for function on defecation. All 32 patients have been continent, of those who needed laxatives were 11 (34.3%) due to constipation and overflow incontinence. Four children (12.5%) have remained dependent on laxatives. Laparoscopic-assisted endorectal pull-through operation for Hirschsprung's disease appears to be safe, provides the less pain, shorter time to full feeding, shorter hospital stay, and excellent cosmetic outcomes. Helping patients and parents ensure the quality of life, they should be provided with counseling, education, and longer-term follow-up care.

복강경 부신 절제술: 111예 경험

차정환,설지영,Jeong-Hwan Cha,Ji-Young Sul 대한갑상선-내분비외과학회 2013 The Koreran journal of Endocrine Surgery Vol.13 No.4

Purpose: Laparoscopic adrenalectomy has become the standard of care for a variety of benign adrenal pathologies. A total of 111 consecutive adrenalectomies were performed using a lateral transperitoneal or posterior retroperitoneal approach, each with its own inherent benefits and shortcomings. The authors compared the effectiveness and safety of posterior retroperitoneal adrenalectomy (PRA) with that of lateral transperitoneal adre-nalectomy (LTA). Methods: Medical records of 111 patients diagnosed with adrenal tumor who underwent laparoscopic adrenalectomy from January 2000 through April 2012 at Chungnam National Hospital were reviewed retrospectively. Study variables included operative time, length of hospital stay, number of days of pain control, diet beginning and advance, and compli-cations. Results: PRA was shorter in most variables, including operative time, hospital stay, first diet beginning, and full diet advance time compared with that of LTA. In pheochromocytoma less than or equal to 7 cm in size, operation time for LTA was longer than that of PRA. One PRA-specific complication was pseudo-hernia of the ipsilateral abdominal wall, which was resolved spontaneously within 1∼2 months. Conclusion: Laparoscopic adrenalectomy is a safe and effective approach to benign adrenal pathology, and PRA should be considered in patients with tumors less than or equal to 7 cm.

위체부에 발생한 조기위암에서 위구획절제술과 Billroth I 재건술식의 비교

송민상,이상일,설지영,노승무,Song, Min-Sang,Lee, Sang-Il,Sul, Ji-Young,Noh, Seung-Moo 대한위암학회 2009 대한위암학회지 Vol.9 No.4

목적: 위체부에 발생하는 조기위암에 대해 원위부 위아전 절제술(SDG)이 표준 술식으로 시행되나 술 후 기능장애와 합병증이 있으며, 이런 단점을 최소화하기 위해 내시경적점막절제술을 하지만 림프절의 전이여부를 알 수 없는 단점이 있다. 위의 절제 범위를 줄이고 유문을 보존하고, 림프절의 절제가 가능한 위구획절제술(SG)에 대해 그 유용성을 평가하고자 한다. 대상 및 방법: 2004년 1월부터 2007년 7월까지 본원에서 위체부의 조기위암 환자 중 41명에서 SG를 하였고, 40명에서는 SDG를 하였다. 의무기록 및 전화를 이용한 설문을 이용하여 수술 후 6개월과 12개월의 영양상태와 술 후 합병증에 대해 두 군을 비교하였다. 결과: 영양상태의 변화(혈색소, 혈장단백, 혈장알부민, 혈장콜레스테롤, P>0.05)와 체중의 변화에서 유의한 차이는 보이지 않았다. SG군에서 SDG군에 비하여 내시경 시 잔여음식물(P<0.05)이 많았으나, 상복부 불편감이나 식사 시조기 팽만감에는 큰 차이가 없었다(P>0.05). 식도염은 두군에서 비슷한 발생률을 보였고(P>0.05), 담즙 역류는 SG군과 SDG군에서 각 한 명만 관찰이 되었다. 결론: SG군에서는 유문이 보존되므로 담즙 역류로 인한식도염, 위염의 발생 감소와, 위절제범위의 감소와 유문보존으로 인한 영양학적인 장점을 기대하였으나, 현재까지의 결과는 두 군에서 큰 차이를 발견할 수 없었다. SG의 장점과 단점을 알기 위해서는 더 오랜 기간의 경과관찰과 연구가 필요할 것으로 생각한다. Purpose: Subtotal distal gastrectomy has been accepted as the standard treatment for early gastric cancer that's developed on the gastric body. EMR and ESD have been introduced to minimize the incidence of postgastrectomy syndrome, but these procedures can not detect lymph node metastasis and they have a risk for gastric perforation. Segmental gastrectomy has recently been applied for treating early gastric cancer, but its usefulness has not been clarified. The aim of this study was to compare segmental gastrectomy and distal gastrectomy with Billroth I reconstruction for treating early gastric cancer that's developed on the gastric body. Materials and Methods: We performed a retrospective review of all the patients who were diagnosed as having early gastric cancer that developed on the gastric body at Chungnam National University Hospital from January 2004 through July 2007. During this period, 41 patients received segmental gastrectomy and 40 patients underwent subtotal distal gastrectomy. All the patients were studied via a biannual review of the body systems, a physical examination, endoscopy, computed tomography and the laboratory findings. Results: There were no significantly differences of the clinicopathologic characteristics between the two groups. The changes of the nutritional status (Hb, TP, Alb and TC) and the body weight change were not significantly different between the 2 groups. There were significantly more residual food in the SG group than that in the SDG group (RGB classification, Residual>Grade 2), but there were no differences for epigastric discomfort (P>0.05). Esophagitis developed at a similar rate for both two groups (LA classification, >Grade A), and bile reflux was found in only one patient of each group. Conclusion: We expected the reduction of esophagitis and gastritis and the improvement of nutritional status according to the type of procedure. Yet the results of our study showed no significant differences between the two study groups. More patients and a longer follow up time are needed for determining the advantage sand disadvantages of segmental gastrectomy.

이소성 췌장과 위점막을 가진 멕켈 게실에 의한 장중첩증 1예

김미진,김재영,설지영,강대영,Kim, Mi Jin,Kim, Jae Young,Sul, Ji Young,Kang, Dae Young 대한소아소화기영양학회 2006 Pediatric gastroenterology, hepatology & nutrition Vol.9 No.1

저자들은 장중첩증의 관장 정복 후 입원 관찰 기간 동안에 2차례 더 재발한 장중첩증을 가진 5세여 아에서 복부 CT 촬영으로 선두를 확인하고 복강경으로 치료한 이소성위점막과 췌조직을 동시에 가진 멕켈 게실에 의한 장중첩증 1예를 경험하였기에 문헌 고찰과 함께 보고한다. Intussusception is a frequent cause of intestinal obstruction in early childhood and most are idiopathic in origin. In a minority of cases a definite pathological lead point is identified by imaging studying or during surgery. As the pathologic lead point of intussusception, Meckel's diverticulum is the most common lesion. In symptomatic patients, 40~60% of Meckel's diverticulum contain ectopic tissue, with gastric mucosa being far the most common type. A few Meckel's diverticulum contain pancreatic tissue. Combined heterotopic pancreatic and gastric tissues in the Meckel's diverticulum especially causing intussusception is extremely rare. We report the case of 5-year-old girl with an intussusception caused by Meckel's diverticulum containing both heterotopic gastric and pancreatic tissues.

소아에서 발생한 위장관 간질 종양 1예

윤경빈,김재영,유재홍,설지영,강대영,Yun, Kyung-Bin,Kim, Jae-Young,Ryu, Jae-Hong,Sul, Ji-Young,Kang, Dae-Young 대한소아소화기영양학회 2007 Pediatric gastroenterology, hepatology & nutrition Vol.10 No.1

저자들은 2년 전부터 식사 후에 주로 나타나는 간헐적인 상복부 복통이 있어오다가 한 차례 흑혈변을 보여인근 병원에서 시행한 혈액검사에서 빈혈을 보여 전원된 10세 여아에서 소아에서는 발생이 드물다고 알려진 위에서 발생한 GIST 1예를 경험하였기에 문헌고찰과 함께 보고한다. Gastrointestinal stromal tumors (GISTs) are the most common primary mesenchymal tumors of the digestive tract. They have been commonly observed in adults but have been rarely described in children. They arise typically from the intestinal wall and rarely in the mesentery, omentum, or retroperitoneum. GISTs originate from the interstitial cell of Cajal and are characterized by overexpression of the receptor tyrosine kinase c-kit. Up to 94% of these tumors express the CD117 on immunohistochemical stain. Surgery is the main modality of treatment for primary resectable GIST. Completely resectable GIST with low risk has excellent prognosis after primary surgical intervention, with over 90% of the 5-year survival. We report a case of 10-year-old girl presenting with an upper gastrointestinal bleeding caused by gastrointestinal stromal tumor.

합병성 충수염에서 1차 선택 수술로서 복강경 충수절제술의 안전성

박준범(Jun-Beom Park),설지영(Ji-Young Sul) 대한외과학회 2007 Annals of Surgical Treatment and Research(ASRT) Vol.72 No.1

Purpose: We performed a study comparing the morbidity of laparoscopic and open appendectomy to assess whether laparoscopic appendectomy could be an initial procedure of choice for patients suffering with complicated appendicitis (gangrene, perforation and periappendiceal abscess). Methods: We studied the patients who underwent appendectomy by either a laparoscopic or an open technique at Chungnam National University Hospital between January 2003 and July 2006. There were 118 patients in the laparoscopic appendectomy (LA) group and 232 patients in the open appendectomy (OA) group. Results: The operating times and length of hospital stay were significantly shorter for the LA group than for the OA group (P<0.05). Five patients (4.2%) underwent conversion from LA to OA, but none of these patients showed more of a propensity for complications compared with the OA group. 51 of the 350 patients (14.6%) had 67 postoperative complications, including wound infection, intraabdominal abscess, ileus (>72 hours) and small bowel obstruction. Complications were less frequent after LA compared with OA (10.2% vs 23.7%, respectively)(P=0.01). There were less wound infections in the LA group than in the OA group (8.5% vs 14.2%, respectively)(P=0.02), and all the complications were minor compared with that for the OA group. A postoperative intraabdominal abscess developed in one patient in the OA group, but this didn’t occur in the LA group. There were no serious complications requiring readmission or reoperation in the LA group. Conclusion: LA showed a significant benefit over OA in this study. The findings suggest that LA could be a safe primary choice for treating complicated appendicitis. To reach a final consensus on the scope of this study, a prospective randomized controlled study is needed in the near future.

흉부 종괴로 오인된 선천성 식도열공 탈장 1례

노혜미,문은경,이동철,임혜경,유재홍,설지영,김종철,Rhou, Hye-Mi,Moon, Eun-Kyung,Lee, Dong-Chul,Im, Hye-Kyung,Yu, Jae-Hong,Sul, Ji-Young,Kim, Jong-Chul 대한소아소화기영양학회 1999 Pediatric gastroenterology, hepatology & nutrition Vol.2 No.2

The esophageal hiatal hernia is a herniation of an abdominal organ, usually the stomach, through the esophageal hiatus into thoracic cavity. It is a rare disease, usually congenital and frequently associated with gastroesophageal reflux and other congenital malformations in children. It is classified according to their anatomic characteristics as type I (sliding hiatal hernia), type II (paraesophageal hiatal hernia), type III (combined hiatal hernia) and type IV (multiorgan hiatal hernia). We experienced a case of type III congenital esophageal hiatal hernia simulating chest mass on simple chest x-ray because of right intrathoracic stomach secondary to congenital esophageal hiatal hernia and organoaxial rotation in 10 months male. After the operation, he showed an improved general condition and was discharged at the 14th hospital day. We report the case with the brief review of the related literatures. 식도열공 탈장은 그 형태에 따라 진단 및 치료가 지연될 경우 반복되는 구토, 빈혈, 영양실조, 출혈, 감돈, 위궤양, 급성 위팽만 등의 합병증이 발생하여 치명적일 수 있다. 저자들은 심한 탈수와 영양 실조를 주소로 내원한 10개월 남아에서 단순 흉부촬영에서 우측 흉부 종괴로 오인되었으나 선천성 식도열공 탈장과 위의 회전에 의해 상부 위장관 바륨조영술에서 우측 흉강내에 위가 위치한 것처럼 보였던 경우로 탈장 정복술과 위식도 역류방지술을 시행한 후 상기 증상이 호전된 제 3형의 선천성 식도열공 탈장 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

위장관 기질종양의 10년 수술 성적

이경하(Kyung-Ha Lee),송인상(In-Sang Song),설지영(Ji-Young Sul),김지연(Ji-Yeon Kim),전광식(Kwang-Sik Chun),이상일(Sang-Il Lee),강대영(Dae-Young Kang),최송이(Song-I Choi),노승무(Seung-Moo Noh) 대한외과학회 2010 Annals of Surgical Treatment and Research(ASRT) Vol.78 No.6

Purpose: Gastrointestinal stromal tumors (GISTs) possess highly variable clinical behaviors and the study thereof is insufficient. There are no standard guidelines for diagnosis and treatment of GISTs, so it is difficult to predict recurrences and conduct appropriate treatments. Throughout the last 10 years of experiences with GIST patients, we have identified the variables predicting recurrences and classified the risk groups by NIH classification, Fletcher risk stratification and UICC TNM stage. Methods: From January 1998 to December 2007, 88 patients with pathologic confirm and surgical resection were diagnosed with GISTs. GISTs were diagnosed when the tumor had characteristic histologic features and confirmed positive by KIT, CD34, or PDGFRA. Results: The size, mitotic index, existence of symptoms, and origins of tumor correlate statistically with recurrence (0.002, <0.001, 0.027, 0.011). The NIH classification, Fletcher risk stratification and UICC TNM stage are correlated with recurrence (0.001, <0.001, <0.001) and 5 year disease free survival, statistically (0.009, <0.001, <0.001). Fifteen patients experienced recurrences. 14 patients were treated with imatinib, and 6 of them showed a response to the treatment. All 4 patients who had R1 resection did not survived due to the progression of the disease. Conclusion: The patients with large, high mitotic index, symptomatic, or extra-gastric tumor require strict surveillance. Also, patients with low risk must be under surveillance due to the possibility of recurrence. It is important to perform R0, en bloc resection. Although the imatinib is the treatment of choice with recurred or metastatic GISTs, the disease is likely to develop resistance, further studies on newly targeted therapy is in need.