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서진,김세년,이갑렬,김소영,박상대,홍승환,Seo, Jin,Kim, Se-Nyun,Lee, Gap-Ryol,Kim, So-Young,Park, Sang-Dal,Hong, Seung-Hwan The Korean Society for Integrative Biology 1997 Korean journal of biological sciences Vol.1 No.2
We examined the effect of modulation of PKA isozymes on the growth of human ovarian cancer cells. Three ovarian cancer cell lines, 2774, SK-OV-3, and OVCAR-3, were examined in this study. The treatment of 5 uM 8-CI-cAMP, which has been known to down-regulate RI (or type 1 PKA) and up-regulate RII (or type II PKA), markedly inhibited the growth of all cell lines (50-80% at day 6). To test whether alteration in PKA regulatory subunits level can change the growth characteristics of ovarian cancer cells, we introduced RIIB- expression construct and Rla antisense-expression construct into 2774 cells. The overexpression of RIIB down-regulated Rla protein, and the antisense-expression of Rla up-regulated RIIB protein, showing that the intracellular levels of RI and RII are reciprocally regulated. In both cases, cell growth was reduced by 30% at day 2. These results indicate that the growth of ovarian cancer cells is controlled by the signals from PKA isozymes, and the modulation of PKA isozymes can be employed for the human ovarian cancer therapy.
抗战岁月里韩中游击队员互动的叙事 ‐ 以《八月的乡村》、《满洲琐记》、《边陲线上》、《金英》为中心
서진,박재우 중국학연구회 2010 중국학연구 Vol.- No.54
In the area of Anti‐Japanese literature in modern China, there is not lack of the amount of novels about the Korea fighting against the Japan. However, most of them are individual will or organizational movement. Writings about coalition, fighting against Japan, between Korean and Chinese guerrilla are still few. As we have noted, in the modern Korean subject of anti‐invasion novels, that four writings touch the description of the Korean in Chinese guerrilla and their cooperation. Writers, as for choosing these subjects, not only dispel Chinese misunderstandings about the Korean but also raise new subjects about international cooperation between Korean and Chinese guerrilla. This writing is to discuss these four novels about (anti‐Japanese) Korean guerrilla, and to delineate the characterization and narration of these four novels. Also, a wish of providing more profuse perspectives about Korean novel toward modern Chinese is embodied.
컬러 영상에서 Support Vector Domain Description을 이용한 얼굴 검출
서진,고한석,Seo Jin,Ko Hanseok 대한전자공학회 2005 電子工學會論文誌-SP (Signal processing) Vol.42 No.1
본 논문에서는 컬러 영상에서 Support Vector Domain Description (SVDD)를 이용한 얼굴 검출 방법을 제안한다. 기존의 훈련을 통한 얼굴 검출 방법은 얼굴 영상과 얼굴이 아닌 영상을 모두 사용해야 한다. 그러나, SVDD를 이용한 얼굴 검출은 단지 훈련을 위해 얼굴 영상만이 사용된다. SVDD의 훈련을 통해 나오는 값인 반지름과 중심 좌표를 통해 얼굴을 검출한다. 또한, 엔트로피를 이용한 임계값 추출 방법(Entropic Threshold)을 통해 얼굴 특징을 추출하고, 슬라이딩 윈도우(sliding window)기법을 통해 성능을 개선한다. 주성분 분석(Principle Component Analysis) 과 SVDD를 이용한 얼굴 검출 방법의 비교 실험을 통해 본 논문이 제안한 방법의 효율성을 확인한다. In this paper, we present a face detection system using the Support Vector Domain Description (SVDD) in color images. Conventional face detection algorithms require a training procedure using both face and non-face images. In SVDD however we employ only face images for training. We can detect faces in color images from the radius and center pairs of SVDD. We also use Entropic Threshold for extracting the facial feature and sliding window for improved performance while saving processing time. The experimental results indicate the effectiveness and efficiency of the proposed algorithm compared to conventional PCA (Principal Component Analysis)-based methods.