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Flow Cytomery를 이용한 DNA 분석과 고형종양의 예후
백승언,신연명,이승도 고신대학교(의대) 고신대학교 의과대학 학술지 1992 고신대학교 의과대학 학술지 Vol.8 No.2
Flow cytometric DNA content analysis is a rapid, quantitative method of determining the DNA ploidy status and proliferative index of a given tumor. Aneuploidy is present in 60-70% of solid tumors and has been recognized as a marker of malignancy and unfavorable prognosis. Also, high S-phase fraction has been recognized as an expression of biological aggressiveness and poor prognosis. This method has been applied widely to many kinds of malignant tumors to evaluate it's prognostic significance and possibility of clinical application. But the results are still contriversial according to the exminers and kinds of tumors. To evaluate prognostic significance of this method in gastric carcinoma we examined DNA ploidy and survival time of 235 gastric cancer patients who underwent opertions at the Departement of Surgery, Kosin Medical College between Jaunuary 1979 and June 1981, and the results were compared with other prognostic factors such as TNM atage, histologic grade, Lauren's classification and patient' age along with a collective review of recent literatures.
백승언 고신대학교(의대) 고신대학교 의과대학 학술지 1992 고신대학교 의과대학 학술지 Vol.8 No.1
-Abstract- 37 cases of snuffbox arteriovenous fistulas were performed at Kosin medical college between March 1991 and September 1992. The procedure which was first reported by Mehigan in 1982, was modified by auther. The advantages of this procedure were technically easier with minimal dissection, more distally located and offers another chance of Brescia-Cimino fistula. The patency rate was 89.7% as a first procedure. So it is advisable as a first choice of internal arteriovenous fistula.