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성수동 준공업지역 블럭단위 개발에 관한 연구-기존 도시조직의 리노베이션과 확장
박윤정(Park, Yun-Jung),안기현(Ahn, Kee-Hyun) 대한건축학회 2016 대한건축학회 학술발표대회 논문집 Vol.36 No.2
Many old places in Seoul are erased because of massive redevelopment. High rise buildings, taking spaces instead of old city tissues that remind citizen of their lives and history, may provide needs of density in city, however it will discard the identity of Seoul. Sungsu-dong is Semi-industrial district located center of Seoul. Many industrials fall behind and became empty. On the other hand, big redevelopment undertaking are held that put neighboring pieces of lots together to build massive offices. This project is a proposal of expansion of remaining uniqe tissue of city satisfying current needs of density.
박윤정(Yun Jung Park),이민수(Min Su Lee),박승수(Seung Soo Park) 한국정보과학회 2005 한국정보과학회 학술발표논문집 Vol.32 No.2
현재 마이크로어레이 기술은 대량의 유전자 발현 데이터 특히 종양과 관련한 데이터들을 쏟아내고 있다. 이 데이터를 기반으로 종양의 종류에 따른 유전자들의 차별적 발현 양상을 분석하고 발현량의 변화가 두드러지는 유전자들에 기반하여 종양을 분별할 수 있는 분류 모델을 구축한 후, 이것을 종양을 진단하거나 예측하는데 이용할 수 있다. 대부분의 종양은 생성 매커니즘에 따라 세부 부류로 나눌 수 있고 세부 부류에 따라 치료 방법이나 예후가 달라지므로, 정확하게 종양의 세부 부류를 진단하는 것이 매우 중요하다. 본 논문에서는 종양의 종류에 따라 발현량이 민감하게 변화하는 유전자들을 뽑아내기 위한 특징 추출 방법들과 추출된 특징들에 기반해서 종양의 종류를 분별할 수 있는 기계학습 알고리즘들의 조합들의 성능을 비교분석 하였다.
제한성 베게너 육아종증(Wegener`s Granulomatosis)과 유사한 양상을 보인 NK/T세포 림프종
박윤정 ( Yun Jung Park ),조철수 ( Chul Su Cho ) 대한류마티스학회 2010 대한류마티스학회지 Vol.17 No.3
It is occasionally difficult to distinguish Wegener`s granulomatosis (WG) from other diseases including malignancy, tuberculosis, and various types of vasculitis because of the overlapping symptoms and signs. We report on a patient with NK/T cell lymphoma who was treated with a limited form of WG. At his first visit, he presented with left foot drop and recurrent nasal swelling. Necrosis and massive infiltration of inflammatory cells were identified on a nasal tissue biopsy. Sural nerve biopsy findings also showed infiltration of inflammatory cells in both the endoneurium and perivascular area; thus, a diagnosis of a limited form of WG was made. After combination therapy with a glucocorticoid and oral cyclophosphamide was initiated, his condition completely recovered without recurrence for the next 2 years. However, he visited the hospital again for recurrence of nasal swelling. Repeated biopsy of nasal tissues, combined with an immunophenotypic analysis revealed NK/T cell lymphoma. The possibility of NK/T lymphoma should be considered when evaluating a limited type of WG, which shows atypical findings on biopsy as well as recurrent deterioration, as a suboptimal dose of immunosuppressive therapy may mask its expression and lead to a poor prognosis.
박윤정 ( Yun Jung Park ),박보형 ( Bo Hyoung Park ),민도준 ( Do June Min ),김완욱 ( Wan Uk Kim ) 대한류마티스학회 2011 대한류마티스학회지 Vol.18 No.1
To determine the degree and risk factors for decreased bone mineral density (BMD) in patients with systemic lupus erythematosus (SLE). Methods. One hundred and one patients with SLE and 57 age-and gender-matched healthy controls were enrolled in this study. The BMD was measured by dual energy X-ray absorptiometry (DXA). The laboratory findings and clinical variables evaluated in the SLE patients consisted of disease duration, SLE disease activity index (SLEDAI), and medications, including mean and cumulative dose of glucocorticoid. At the time of the clinical and laboratory assessment, the levels of serum osteocalcin, serum FSH/ LH, urine deoxypyridinoline (DPD), and serum cytokines, such as IL-6 and soluble receptor activator of NF-kB ligand (RANKL), were determined in SLE patients using a enzyme-linked immunosorbent assay. Results. The BMD T score decreased in patients with SLE compared to the healthy controls (-1.11 versus -0.41, p=0.001 at lumbar spine, -0.84 versus -0.01, p<0.001 at femur neck, -1.20 versus -0.45, p<0.001 at total hip, respectively). Osteoporosis and osteopenia was present in 16.8% and 46.5% of patients, respectively. Multiple regression analysis revealed a low BMD in the lumbar spine to be associated with increased FSH, low BMI and cumulative glucocorticoid dose. A low BMD in the hip and femur neck was associated with increased FSH, low BMI, and duration of glucocorticoid. On the other hand, the levels of osteocalcin, deoxypyridinoline (DPD), IL-6, and soluble RANKL were similar in patients with a low BMD and those with normal BMD. Conclusion. Osteoporosis and osteopenia are more common in young Korean SLE patients than in control subjects. Elevated FSH, low BMI, and the use of glucocorticoid are independent risk factors linked to a decreased BMD in Korean patients with SLE.
대장암 선별검사로서 대장 용종 발견에 대한 CT 대장조영술의 유용성
박윤정 ( Yun Jung Park ),정승은 ( Seung Eun Jung ),박신애 ( Shin Ae Park ),김지희 ( Jee Hee Kim ),장은희 ( Eun Hee Chang ),고명범 ( Myoung Beom Koh ),정대영 ( Dae Young Cheung ),김진일 ( Jin Il Kim ),조세현 ( Se Hyun Cho ),박수헌 대한내과학회 2008 대한내과학회지 Vol.75 No.4
목적: CT 대장조영술은 나선형 CT를 이용하여 대장의 영상을 얻는 빠르고 비침습적인 검사 방법으로 대장의 용종 발견에 이용되고 있다. CT 대장조영술에서 용종 발견을 위해 용종선별 크기를 얼마로 정의하는 것이 적당한 지를 알아보았다. 방법: 84명(평균나이 55.7±11.1세; 남자 52명, 여자 32명)의 대상자에서 대장내시경검사 전 CT 대장조영술검사를 하였다. CT 대장조영술을 시행하여 얻은 결과는 용종의 크기를 모든 크기의 용종, 5 mm 이상, 7 mm 이상, 10 mm 이상의 용종으로 누적 분류하고 용종의 위치, 형태, 조직학적 소견을 조사하였다. 대장내시경검사 결과를 참고 기준으로 CT 대장조영술검사 결과의 민감도를 평가하였다. 결과: CT 대장조영술과 대장내시경검사를 시행한 대상자 중 26명에게서 56개의 용종이 확인되었다. 용종 선별 크기를 모든 크기의 용종, 5 mm 이상, 7 mm 이상, 10 mm 이상으로 정의하였을 때 CT 대장조영술검사의 민감도는 각각 60.7%, 70.5%, 75.9%, 81.8%였다. 대상자별 민감도는 각각 80.7%, 95.0%, 93.3%, 90.9%였고, 특이도는 각각 86.8%, 89.8%, 95.3%, 100.0%였다. 편평형 용종, 무경성 용종, 유경성 용종을 발견하는 CT 대장조영술의 민감도는 각각 30.8%, 85.0%, 90.0%였다. 결론: CT 대장조영술검사는 용종선별 크기를 7 mm 이상으로 하였을 때 민감도 75.9%, 양성예측값 71.0%로 신뢰할 수 있는 검사였다. Background/Aims: CT colonography is a rapid and safe imaging method for detecting polyps in the colon and rectum. We assessed the efficacy of CT colonography in colorectal polyp detection. Methods: We prospectively studied 84 subjects (mean age 55.7±11.1 years; 52 men, 32 women) undergoing CT colonography followed by colonoscopy. Based on the results of CT colonography, all polyps were classified by size (any size, and those larger than 5, 7, and 10 mm) and were checked for location, morphology, and histological characteristics. We determined the sensitivity and specificity of CT colonography using colonoscopy as a reference standard with a segmental unblinding method. Results: A total of 56 lesions were identified in 26 of 79 subjects undergoing both CT colonography and conventional colonoscopy. The sensitivities of CT colonography for polyps of any size, and larger than 5, 7, and 10 mm were 60.7%, 70.5%, 75.9%, and 81.8%, respectively. The per-subject sensitivities of CT colonography for the polyps of any size, and larger than 5, 7, and 10 mm, were 80.7%, 95.0%, 93.3%, and 90.9%, respectively. The per-subject specificities of CT colonography for polyps were 86.8%, 89.8%, 95.3%, and 100.0%, respectively. The sensitivities of CT colonography for flat, sessile, and pedunculated polyps were 30.8%, 85.0%, and 90.0%, respectively. Conclusions: CT colonography is a useful diagnostic method for screening colorectal neoplasias larger than 7 mm diameter, showing 75.9% sensitivity and 71.0% positive predictive value. (Korean J Med 75:420-427, 2008)
집단미술치료가 유아의 정서지능, 문제행동 및 적응력에 미치는 효과
박윤정(Yun-Jung Park),이미선(Mi-Sun Lee) 한국예술심리치료학회 2023 예술심리치료연구 Vol.19 No.1
본 연구는 집단미술치료가 유아의 정서지능, 문제행동 및 적응력에 미치는 효과를 검증하고자 하였다. 연구대상은 유아교육기관에 재원 중인 만 4-5세의 유아이며, 이들의 보호자 및 교사에게 본 연구의 목적을 설명하여 최종 동의를 얻은 대상에 한하였다. 최종적으로 연구 참여에 동의한 유아 16명은 실험집단 8명, 통제집단 8명으로 배정하였다. 측정도구로는 교사용 유아의 정서지능 척도(EI), 교사용 문제행동평가(C-TRF), 유아의 어린이집 적응 척도(ISCS)를 사용하였다. 실험집단은 2019년 6월부터 2020년 1월까지, 주 1회, 회기 당 40-45분씩 총 18회기의 집단미술치료를 진행하였고, 통제집단은 무처치하였다. 자료분석은 IBM SPSS Statistics Ver. 22.0 프로그램을 사용하였다. 본 연구 결과는 다음과 같다. 첫째, 집단미술치료를 실시한 실험집단은 통제집단에 비해 정서지능 요인에서 통계적으로 유의한 변화가 나타났다. 둘째, 집단미술치료를 실시한 실험집단은 통제집단에 비해 문제행동 요인이 유의하게 감소하였다. 셋째, 집단미술치료를 실시한 실험집단은 통제집단에 비해 적응력 요인에서 통계적으로 유의한 차이가 나타났다. 본 연구는 집단미술치료 프로그램의 효과성 검증을 시행함으로써, 유아를 대상으로 한 심리사회적 개입의 가능성 및 효과를 모색해볼 수 있었다는 점에서 연구의 의의를 가진다. The study aimed to examine the effects of group art therapy on emotional intelligence, problem behaviors, and adaptive abilities of preschool children. The subjects of the study were preschool children (4-5 years) enrolled in early childhood education institutions, and the final consent was obtained from their guardians and teachers. Of the 16 preschool children, eight were assigned to the experimental group and the control group, respectively. The assessment tools were the Emotional Intelligence (EI), Caregiver-Teacher Report Form (C-TRF), and Iowa Social Competency Scale Preschool Form (ISCS). The experimental group participated in eighteen sessions of group art therapy, once a week with each session lasting 40-45 minutes, from June 2019 to January 2020. In addition, the control group was untreated. The statistical analyses were performed using IBM SPSS Ver. 22.0. The results were as follows. First, the experimental group showed a statistically significant change in emotional intelligence, compared to the control group. Second, the experimental group showed a statistically significant decrease in problem behaviors, compared to the control group. Third, the experimental group showed a statistically significant difference in adaptive abilities, compared to the control group. Our study demonstrated that group art therapy has positive effects on reducing problem behaviors and improving preschool children's emotional intelligence and adaptive abilities.