http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 남동기 ( Dong Ki Nam ) (검색결과 20 건)
- 무료
- 기관 내 무료
- 유료
-
-
환삼덩굴 ( Humulus Japonicus ) 화분에 대한 피부 반응도 및 특이 IgE 의 측정에 관한 연구
남동기(Dong Ki Nam),박해심(Hae Sim Park),오승헌(Seung hun Oh),홍천수(Chein Soo Hong) 대한내과학회 1988 대한내과학회지 Vol.35 No.2
N/A To assess the clinical contribution of Humulus japonicus pollen which is thought to be an important causative pollen of the pollinosis in Autumn as are ragweed and sagebrush in Korea, a total of 340 patients with allergic respiratory disease visiting the allergy clinic in Severance Hospital, Yonsei University College of Medicine from March 1986 to February 1987 were studied. These patients (bronchial asthma 108, allergic rhinitis 97, bronchial asthma with allergic rhinitis 41 and other 94 cases) were tested for their skin reactivity to the extracts of Korean and Torii`s Humulus japonicus pollen, Dermatophagoides farinae, sagebrush, and rag- weed. Micro-ELISA was used to determine the Humulus japonicus-specific IgE level in 120 sera from patients who showed a positive skin test (more than 2+) to the Torii`s Humulus japonicus. The following results were obtained: 1) The global results of the skin prick test to the extract of Korean pollen of Humulus japonicus were negative in 64.0%, 1+ in 22.1%, 2+ in 11.8%, 3+ in 1.8%, and 4+ in 0.3% of 340 cases. The positive skin test rate (more than 2+) among the disease entities for the Korean and Toriis extracts of Humulus japonicus pollens respectively were 14.9% and 8.4/o in bronchial asthma; 17.5% and 21.6% in allergic rhinitis; 17.1% and 26.9% in bronchial asthma with allergic rhinitis; and 7. 7% and 6.3% in the others 2) The positive skin test rate for Korean Humulus japonicus in those patients who showed a positive skin test to Torii`s Humulus japonicus was 42.6% and the positive skin test rate of for Torii`s Humulus japonicus in those patients who showed a psotive skin test to Korean Humulus japonicus was 42.6% also. The correlation between the skin test results of the extracts of Korean and Torii`s Humulus japonicus pollen was very weak (r=0.41, p<0.05). 3) The positive skin test rates for Korean Humulus japonicus in patients who showed positive (more than 2+) and negative (less than 1+) skin tests to D. fariae, sagebrush and ragweed were 23.5%, 6.3% and 33.3%, 9.6% and 46.4%, 9.4% respectively (p<0.01). 4) The cut-off value of optical density (OD) in ELISA for Humulus japonicus-specific IgE was calculated from 30 negative control sera by computing its mean and standard deviation (Mean+2.S.D.=0.012) and forty-five (37.5%) of 120 patients' sera were ELISA positive. And the correlation between wheal size resulting from the skin prick test and the OD value of ELISA for the specific IgE of Humulus japonicus pollen was very weak (r=0.23 with Korean; r=0.12 with Torii`s). 5) The ELISA positive rates in patients who showed a positive skin test (more than 2+) to Korean and Torii s Humulus japonicus respectively were 46.2% and 50.0 %; and the ELISA positive rate in the negative skin test group was 40.3% and 32.5%. 6) The ELISA inhibition test with sera from 4 patients with high OD value (more than 0.1) showed that 2 patients were definitely inhibited upon the addition of the extract of Korean Humulus japonicus pollen extract, demonstrating Humulus japonicus specific-IgE in the patients sera. 7) The correlation between total serum IgE level and the OD value of ELISA was very weak (r=0.17), showing little effect of a high total IgE level on the results of ELISA. The ELISA positive rate was 41.7% in 12 sera with total serum IgE level of more than 500 IU/ml and 40.0% in 75 sera with a level of less than 500 IU/ml. The author could conclude that both skin test reactivity and OD value using micro-ELISA with the extract of the Korean pollen of Humulus japonicus were relatively low and consequently the allergenicity of it was minimal with the above data. The ultimate outcome in the evaluation of the skin test result with OD value in micro-HLISA to determine the specific IgE level must await further exhaustive research using a more highly purified extract of Humulus japonicus pollen.
-
-
-
증례 / 제생 불량성 빈혈과 신증후군이 동반된 전신성 홍반성 낭창 환자에서 plasma filtration 과 synchronized cyclophosphamide 치료 1예
박해심(Hae Sim Park),김현수(Hyun Soo Kim),남동기(Dong Ki Nam),박지원(Jee Won Park),최소연(So Yeon Choi),김효철(Hugh Chul Kim),김희연(Hee Yeon Kim),남동호(Dong Ho Nahm) 대한내과학회 1999 대한내과학회지 Vol.56 No.1
Systemic lupus erythematosus(SLE) is a multisystemic autoimmune disease. In rare case, aplastic anemia can develop as a complication of SLE. We report a case of SLE patient with aplastic anemia and nephrotic syndrome. A 33-year-old woman was admitted because of gum bleeding. After laboratory work up including bone marrow biopsy study, she was diagnosed as SLE with aplastic anemia and nephrotic syndrome. The patient was initially treated with high dose steroid pulse therapy. However the patient did not responded to high dose steroid treatment. We treated the patient with plasma filtration and synchronized cyclophosphamide thrapy followed by monthly intravenous cyclophosphamide treatment. Complete clinical remission of hematologic and renal complications was achieved in this patient. We suggest that plasma filtration and synchronized cyclophosphamide therapy might be one of efffectie treatment modality in the management of severe SLE patient.
-
-
-
-
급성전골수성백혈병에서 백혈구성분채집술에 이은 치명적인 뇌출혈 2예
오윤정,박소윤,김윤정,한동석,김현수,최진혁,남동기,임호영,김효철,주희재 아주대학교 의과학연구소 1998 아주의학 Vol.3 No.1
The aim of this study is to report 2 cases of acute promyelocytic leukemia who died from intracranial hemorrhage following leukapheresis and to provide proper preventive measures against hemorrhage following leukapheresis. From 1994 to 1997, a total of twenty-six patients with leukemia underwent leukapheresis to control hyperleukocytosis at Ajou University Hospital. Two patients with acute promyelocytic leukemia received all-trans retinoic acid but developed drug-induced hyperleukocytosis. Shortly after leukapheresis, they died from intracranial hemorrhage. The risk factors for fatal hemorrhage are thought to be coexisting disseminated intravascular coagulation(DIC), thrombocytopenia aggravated by leukapheresis, exacerbated coagulopathy related to mechanical trauma through leukapheresis and the excess use of citrate during leukapheresis. To reduce the risk of the bleeding associated with leukapheresis, it is necessary to replace platelet sufficiently before and after leukapheresis and to give calcium to correct coagulopathy induced by excess citrate which is used as anticoagulant as well as the correction of disseminated intravascular coagulation.
-
급성 골수성 백혈병에 동반된 간-비(肝-脾) 칸디다증 3 예
이선주,남동기,이종태,한지숙,박준용,고윤웅 대한내과학회 1989 대한내과학회지 Vol.36 No.1
Reported here 3 cases of hepatosplenic candidiasis complicated in acute myelogenous leukemia. All cases rvealed persistent fever, hepatosplenomegaly, abdominal symptoms and increased alkaline phosphatase in 2 of 3 cases. Rather typical mu1tiple cystic lesions with a target sign in the liver and spleen had noted on the abdominal ultrasonogram and computed tomography. The ultrasonogram guided needle aspiration obtained yeasts and pseudohyphae which were confirmed on micorcopic exdmination. We suggested prompt and repeated radiological studies (ultrasonogram and/or CT scan) in these patients with the above symptoms, especially those symptoms which developed during the period of hematological improvement after induction chemotberapy.
ScienceON연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
