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김은서,이지수,이현규 한국식품과학회 2016 Food Science and Biotechnology Vol.25 No.5
Catechin-loaded Ca-alginate beads and microparticles were prepared by an emulsion gelation method using sunflower oil for efficient sustained release of catechin. The emulsion was prepared by sequential mixing of alginate, oil, and oleic acid ester as an emulsifier. Encapsulation efficiency (EE) and inhibition of catechin release of the beads were significantly increased approximately to 453.83 and 148.71% by the emulsion gelation technique, respectively (p<0.05). For the microparticles, the highest inhibition of catechin release after 1 h of incubation (78.82%) was observed at the microparticles prepared by 5% (w/w) oil, 3% (w/w) alginate, 4% (w/v) CaCl2, and 200 mg catechin with the most hydrophilic emulsifier, decaglycerol mono-ester. Moreover, the catechin release was sustained at acidic conditions and increased with increase in pH of release medium. These results suggest that catechin encapsulation within Ca-alginate particles by emulsion gelation method can be an effective delivery system for catechin.
집단 검진에서 발견된 갑상선 우연암종에 대한 임상적 고찰
김은서,장항석 대한기관식도과학회 2001 大韓氣管食道科學會誌 Vol.7 No.2
Background and Objectives: The introduction of highly sensitive imaging techniques has made it possible to detect many non-palpable nodules, or“incidentaloma”in the thyroid. Discovery of these lesions raises concerns about their malignancy, but the optimal strategy for managing these lesions has not been clearly established. This study was designed to evaluate the usefulness of ultrasonographic exam with new diagnostic criteria and presume the value of mass screening for thyroid cancer. Materials and Methods : Mass screening for thyroid cancer were carried out in conjunction with mass screening for breast cancer. The subjects were 630 women aged 30 years or over. Thyroid glands were examined with 10 MHz transducer ultrasonography by one radiologist. Needle aspiration biopsy were performed when suspicious of malignancy under the new diagnostic criteria. Results and Conclusion : The new ultrasonographic criteria to diagnose thyroid cancer provided useful information and ensured more accurate evaluation. 7 cases of thyroid cancer were discovered and successfully managed. It should be further demonstrated that there is sufficient value of mass screening for thyroid cancer to perform it independently despite early cancer detection.
오심, 구토, 복통으로 인해 급격한 체중감소를 보인 환자 치험 1례
김은서,손종석,신길조,Kim, Eun-seo,Son, Jong-seok,Shin, Gil-cho 대한중풍순환신경학회 2015 대한중풍.순환신경학회지 Vol.16 No.1
This patient was 18 year-old man who had severe nausea, vomiting, stomachache but medical examination revealed no abnormality. The symptom lasted for 2 months and he lost 15kilograms. The patient had no underlying diseases. He was treated by korean medicine, containing acupuncture, cupping therapy and herb medicines during 9 days. The severity of nausea was scored by the Numerous Rating Scale and the frequency of vomitng was evaluated by count. After that period, patient's symptom was improved and his other conditions were also better, compared with his admission. This study suggests that Korean medicine could have a therapeutic effect for nausea, vomiting, stomachache and rapid weight loss that the cause has not been diagnosed by Western medicine. It could help to improve patient's symptoms and make general conditions better.
건설 프로젝트 데이터 특성을 반영한 기준생산성 산정 방법
김은서,김준영,주선우,안창범,박문서,Kim Eunseo,Kim Junyoung,Joo Seonu,Ahn Changbum,Park Moonseo 한국건설관리학회 2023 한국건설관리학회 논문집 Vol.24 No.3
This research examines the need for a quantitative and objective method of calculating baseline productivity in the construction industry, which is known for its high volatility in performance and productivity. The existing literature's baseline productivity calculation methods rely heavily on subjective criteria, limiting their effectiveness. Additionally, data collection methods such as the "Five-minute Rating" are costly and time-consuming, making it challenging to collect detailed data at construction sites. To address these issues, this study proposes an objective baseline calculation method using unimpacted productivity BP, a work check sheet to systematically record detailed data, and a data collection and utilization process that minimizes cost and time requirements. This paper also suggests using unimpacted productivity BP and comparative analysis to address the objectivity and reliability issues of existing baseline productivity calculation methods.
김은서,이지수,이현규 한국식품과학회 2015 Food Science and Biotechnology Vol.24 No.5
Catechin-loaded calcium alginate microparticles with high encapsulation and loading efficiencies were prepared using two types of soaking methods; swelling and absorption methods. The soaking methods, respectively, showed approximately 2.4× and 21.7× higher encapsulation and loading efficiencies than the conventional method. Compared with the swelling method, the absorption method showed significantly (p<0.05) higher encapsulation and loading efficiencies that were controlled in the range of 10.6-51.6 and 4.9-38.2%, respectively, under different preparation conditions, including alginate viscosity, blank particle quantity, and the catechin concentration. The absorption method also showed better sustained release in simulated gastric and intestinal fluids and a smaller particle size with uniform morphological properties than the swelling method. The absorption method is a promising method for microencapsulation of catechin.