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갱년기 증후군, 회복탄력성이 중년 남성의 은퇴불안에 미치는 융·복합적 영향
김순애,이송현,홍은희,Kim, Soon-Ae,Lee, Song-Hyun,Hong, Eunhee 대한산업경영학회 2020 산업융합연구 Vol.18 No.4
본 연구의 목적은 중년 남성의 갱년기 증후군, 회복탄력성, 은퇴불안 간의 관계를 융·복합적 측면에서 파악하고 이들 관계를 확인하여 은퇴불안에 영향을 미치는 요인을 파악하기 위함이다. 연구대상은 S시에 거주하는 87명을 대상으로 2019년 7월 20일부터 10월 25일까지 자가 기입식 설문조사를 실시하였다. 연구 결과 중년남성의 은퇴불안은 갱년기 증후군과 회복탄력성이 유의미한 영향력을 갖는 것이 확인되었다. 또한, 갱년기 증후군이 있는 대상자가 증상이 없는 대상자보다 회복탄력성은 낮고, 은퇴불안은 높았다. 따라서 중년남성의 은퇴불안을 효율적으로 극복하기 위해 갱년기 증후군을 감소시키고, 회복탄력성을 증진시킬 수 있는 방안을 고려할 필요가 있다. This study is to identify the relationship between andropause symptoms, resilience, and retirement anxiety in the context of convergence. It is also to identify the factors that affect retirement anxiety by checking these relationships. For data collection, the study surveyed 87 middel-aged men who were residing in S City from July 20 to October 25, 2019. This study found that middle-aged men's anxiety about retirement has a significant influence on andropause syndrome and resilience. In addition, those with andropause syndrome had lower resilience and higher retirement anxiety than those without symptoms. Therefore, it is necessary to consider ways to efficiently overcome retirement anxiety in middle-aged men, reduce andropause symptoms, and enhance resilience.
형태학적으로 고정된 뉴클레오사이드 주요중간체의 Enantioselective 합성법 탐색
김순애(Soon-Ai Kim),김학성(Hak Sung Kim) 대한약학회 2010 약학회지 Vol.54 No.6
Conformationally locked nucleosides are important in searching selective agonists and antagonists for P2Y receptors. There were two previous synthetic works of the crucial intermediate, cyclopentenyl alcohol (3), which had some inefficiency like using too strong dianionic base and synthesis of racemate. Here we describes a facile synthesis of the intermediate using Sharpless epoxidation and the opening of epoxide ring using zinc, followed by Grubb's metathesis as key steps. The intermediate was converted to the southern bicyclo[3.2.0]heptane for confirming its usefulness.
간장 허혈 및 재관류시 Vitamin C 가 간장 기능에 미치는 영향
김순애(Soon Ae Kim),서민영(Min Young Seo),염동호(Dong Ho Yeom),조태순(Tai Soon Cho),이선미(Sun Mee Lee) 한국응용약물학회 1995 Biomolecules & Therapeutics(구 응용약물학회지) Vol.3 No.4
This study was done to investigate the effect of vitamin C on hepatic biliary and microsomal function during ischemia and reperfusion. Rats were treated with vitamin C(20, 100, 400, 1600 ㎎/㎏) or with vehicle(saline) and then subjected to 60 min no-flow hepatic ischemia in vivo. Control animals were time-matched sham ischemic animals. After 1 or 5 hr of reperfusion, bile was collected, blood was obtained from the abdominal aorta, and liver microsomes were isolated. In vehicle-treated ischemic rats, serum ALT and AST levels peaked at 5 hr and were significantly attenuated by vitamin C 20 ㎎/㎏ and 100 ㎎/㎏ treatment. Similarly, hepatic wet weight-to-dry weight ratio was decreased in the vehicle-treated ischemic group. Vitamin C 20 ㎎/㎏ and 100 ㎎/㎏ treatment minimized the increase in this ratio. Lipid peroxidation was elevated in vehicle-treated ischemic group, but this elevation was also inhibited by vitamin C 20 ㎎/㎏ and 100 ㎎/㎏ treatment. Bile flow and cholate output, but not bilirubin output, were markedly decreased by ischemia/reperfusion. Vitamin C 20 ㎎/㎏ and 100㎎/㎏ treatment restored the secretion but vitamin C 1600 ㎎/㎏ reduced the cholate output. Cytochrome P-450 content was decreased by ischemia/reperfusion and restored by vitamin C 20 ㎎/㎏ and 100 ㎎/㎏ treatment to the level of sham operated group but decreased by vitamin C 1600 ㎎/㎏. Aminopyrine N-demethylase activity was decreased and aniline p-hydroxylase activity was increased by ischemia/reperfusion. The changes in the activities of aminopyrine were prevented by vitamin C 20 ㎎/㎏ and 100 ㎎/㎏ treatment, but not by 400 ㎎/㎏ and 1600 ㎎/㎏ treatment. Our findings suggest that ischemia/reperfusion diminishes hepatic secretory functions as well as microsomal drug metabolizing systems, small doses(20, 100 ㎎/㎏) of vitamin C significantly ameliorates and large doses(400, 1600 ㎎/㎏) of vitamin C aggravated these ischemia/reperfusion-induced changes.
김순애 ( Soon Ae Kim ),임지현 ( Ji Hyon Lim ),오진영 ( Jin Young Oh ),박근민 ( Gun Min Park ),김우경 ( Woo Kyung Kim ) 대한천식알레르기학회 2006 천식 및 알레르기 Vol.26 No.4
Spontaneous pneumomediastinum is a rare complication of asthma. During acute attack of asthma alveolar overdistension or rupture due to excessive air pressure results in the leakage of air from the respiratory tract and through dissection along great vessel sheaths to the mediastinum and pericardium. The clinical diagnosis is based on the symptom triads of chest pain, dyspnea, and subcutaneous emphysema, and is also based on Hamman`s sign. The diagnosis is confirmed by chest radiography. The main differential diagnosis is esophageal perforation, which requires esophagography with contrast when there is the slightest doubt in the diagnosis. Management consists of eradication of the underlying cause, rest, analgesics, and simple clinical monitoring. Predisposing factors should be identified and managed to prevent recurrence. We report a case of subcutaneous emphysema in a 15-year-old patient with asthma who presented with spontaneous pneumomediastinum and pneumopericardium. (Korean J Asthma Allergy Clin Immunol 2006;26:310-313)
분만 간호에 대한 시뮬레이션 실습교육과 병원 분만실 실습교육의 효과
김순애 ( Sun Ae Kim ),이선경 ( Sun Kyung Lee ),채현주 ( Hyun Ju Chae ) 여성건강간호학회 2012 여성건강간호학회지 Vol.18 No.3
Purpose: The purpose of this study was to evaluate the effects of clinical practice and simulation-based practice for obstetrical nursing in terms of self-efficacy, practice satisfaction, and practice stress. Methods: A non-equivalent control group post test design was used. The participants were 171 junior nursing students, 103 in the experimental group, and 68 in the control group. Simulation-based practice consisted of nursing assessment during labor, nursing assessment and intervention for normal and high risk mother, nursing education for mother and family during labor, and open lab. The experimental group participated in simulation-based practice for two days and the control group participated in clinical practice at delivery room for two weeks. Results: The experimental group showed higher level of self-efficacy (p=.043), practice satisfaction (p<.001) and practice stress (p=.003) compared to the control group. Conclusion: Simulation-based practice is an effective learning method for obstetrical nursing and can be used as the alternative for clinical practice. However, stress management strategies are needed for simulation-based practice.
김순애(Soon-Ae Kim),강영실(Young-Sil Kang) 한국산학기술학회 2018 한국산학기술학회논문지 Vol.19 No.1
본 연구는 보건진료전담공무원의 개인 심성, 직무연속성, 직무만족 및 전문직업성의 관계를 파악하고 나아가 전문직업성에 미치는 요인을 규명하기 위한 서술적 조사연구이다. 본 연구는 2017년 8월 20일부터 9월 25일까지 G도에 소재하고 있는 보건진료소에 근무하는 보건진료전담공무원을 대상으로 하였으며, 153부를 최종 분석에 사용하였다. 수집된 자료는 IBM SPSS Statistics 20.0 프로그램을 이용하여 기술통계, t-test, ANOVA, Scheffe test, Pearsons"s correlation coefficients, stepwise multiple regression을 통해 분석하였다. 연구결과 대상자의 일반적 특성에 따른 전문직업성 정도의 차이는 월소득(F=6.951, p<.001), 근무경력(F=5.245, p=.002), 보건진료전담공무원 선택동기(F=3.676, p=.004)에서 통계적으로 유의한 차이를 나타냈다. 주요 변수 간의 관계에서 전문직업성은 개인 심성(r=.573, p<.01), 직무연속성(r=.496, p<.01) 및 직무만족(r=.539, p<.01)과 유의한 정적 상관관계를 나타내었다. 일반적 특성, 개인 심성, 직무연속성, 직무만족이 전문직업성에 미치는 영향을 파악하기 위해 다중회귀분석을 실시한 결과, 보건진료전담공무원의 전문직업성과 가장 높은 관련요인은 직무만족(β=.320, p<.001), 개인 심성(β=.291, p<.001), 월 소득(β=.283, p<.001) 및 직무연속성(β=.176, p=.009) 순으로 나타났고, 이들 변인들의 총설명력은 49.6%이었다. 본 연구결과를 바탕으로 보건진료전담공무원의 전문직업성을 강화시킬 수 있는 개인차원과 조직차원에서의 융복합적 프로그램 개발과 정책적 지원이 바람직하다고 본다. This study was conducted to determine factors affecting professionalism of community health practitioners (CHPs). The participants in this study were 153 community health practitioners working in G province with structured self-report questionnaires from 20 August to 25 September 2017. Data were analyzed by descriptive statistics, t-test, ANONA, Scheffe"s test, Pearson"s correlation coefficients and stepwise multiple regression using the SPSS 20.0 program. There were statistically significant differences according to income (F=6.951, p<.001), work experience (F=5.245, p=0.002) and motivation for choosing a community health practitioner (F=3.676, p=0.004). The highest related factors were job satisfaction (β=0.320, p<0.001), individual disposition (β=0.291, p<0.001), income (β=0.283, p<0.001) and job continuance (β=0.176, p=0.009). These variables explained 49.6% of the total variance in professionalism. These findings suggest that it is necessary to develop a convergence program and policy support at the individual and organizational level to strengthen the professionalism of community health practitioners.