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Spray type과 Soot type 입자발생기별 나노입자 개수농도분포 측정특성 비교
김민식 ( M. S Kim ),권지원 ( J. W Kwon ),정명철 ( M. C. Kwon ),이진욱 ( J. W. Lee ) 한국분무공학회 2012 한국액체미립화학회지 Vol.17 No.4
Particulate matters(PM) that is generated by most diesel engine is regulated by the mass concentration measured by the conventional method it had been. Recently, Europe PMP (Particle Measurement Program) decided to start the regulation of vehicle`s nano-sized particle number (PN) from the year of 2011 because of nano-particle`s higher degree of harm to the human body. So firstly, the standard level of PN emission is introduced in the Euro 5/6 emissions regulation with a limit of 6x1011 per km for light duty vehicle. Also KPMP(Korea Particle Measurement Program) was organized to copy quickly international technical trend. In this paper, it was investigated the nano-sized PN measurement characteristics for different particle generators between spray type and soot type. And the difference ratio between particle generators, the characteristic of PN concentration, counting efficiency and linearity was analyzed. Then, we make conclusions as followed. When particle diameter is increased, counting efficiency of two generators is decreased. Also Secondary calibration method is more higher 3% than Primary calibration method. Finally, SOF which is included in soot particles is not totally removed so it have great influence on test result of counting efficiency and linearity.
위식도 역류성질환 관련 인후두역류(Laryngopharyngeal Refulx : LPR)증상을 호소하는 환자에서의 라니티딘의 치료효과 연구
장혁순,고윤우,김광현,김민식,김상윤,김영모,도남용,백정환,안순현,엄재욱,양훈식,우훈영,이형석,Chang, H.S.,Ko, Y.W.,Kim, K.H.,Kim, Y.M.,Kim, S.Y.,Kim, Y.M.,Do, M.Y.,Beak, C.H.,Ahn, S.H.,Eom, J.W.,Yang, H.S.,Woo, H.Y.,Lee, H.S. 대한기관식도과학회 2004 大韓氣管食道科學會誌 Vol.10 No.2
Background : LPRD(Laryngopharyngeal reflux disease) gives rise to inflammatory change in the pharyngolaryngeal tissue with various otolaryngologic symptoms. Ranitidine, histamine H2receptor antagonists, are currently used as therapeutic medications. However, the efficacy of Ranitidine on LPRD has not been proven yet. Objectives : We intended to analyze the efficacy of the Ranitidine on LPRD. Materials :md Methods : In 20 multicenter, 607 patients with LPR(laryngopharyngeal reflux) symptom were observed to evaluate their symptoms and laryngoscopic findings after 4 weeks, 8 weeks, and 12 weeks of treatment of Ranitidine. Results : The symptom of LPR including globus sensation, sore throat hoarseness, regurgitatioin are improved after 4 weeks $86.2\%,\;8 weeks\;91.5\%,\;12 weeks\;92.9\%$ of Ranitidine treatment and improved after 4 weeks $91.5\%,\;8 weeks\;94.5\%,\;12 weeks\; 97.2\%$ of Ranitidine combined with prokinetics. The rates of sore throat, chronic cough, globus sensation improvement at 8 weeks after treatment are $26.7\%,\;16.7\%,\;16\%$. Conclusion : In patient with LPR, Ranitidine treatment reduces LPR symptoms very effectively.
항산화제가 돼지난포란의 체외성숙, 체외수정 및 체외배발달에 미치는 영향
김민식,김은국,위갑인,강만종,문승주,김재홍,조미영,박지현 全南大學校 農業科學技術硏究所 2001 農業科學技術硏究 Vol.36 No.-
This study was conducted to investigate effects of L-ascorbic acid, selenium, α-tocopherol, cysteamine and glutathione on maturation, development ability of porcine oocytes in vitro. When the immature oocytes were cultured of L-ascorbic acid, selenium, α-tocopherol, cysteamine and glutathione for 40-44hr, the nuclear maturation rates were 39.4, 80.9, 82.2, 65.6, 49.1 and 87.9%, respectively. The nuclear maturation rates of treatment groups were significantly(P<0.05) higher than those of non-treat groups. After maturation, the oocytes were inseminated in vitro in medium 199 with ejaculated spermatozoa for examination of cleavage rate and development ability of porcine oocytes. After insemination, the cleavage rates at 48hr of treat groups were higher than thecontrol group(P<0.05), and the cleavage rates at 120hr of treat groups were higher than control group(P<0.05).