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권혁상,황완균,김일혁 중앙대학교 약학연구소 1996 약학 논총 Vol.10 No.-
The Pharmaco-Constituents of the Pulsatilla Koreana Roots, of which roots and rhizomes have been used for the treatment of evil heat, malaria, chill, fever, epistaxis and internal hemorrhoids etc. in Korean folk remedies. From the Ether extract of Roots, two triterpenoidal sapogenins were isolated and elucidated as ursolic acid and oleanolic acid based on their physico-chemical data and IR, EI-MS, ^13C-NMR, and ^1H-NMR analysis with authentics, respectively.
권혁상,이상진,정성태 한국방위산업학회 2014 韓國防衛産業學會誌 Vol.21 No.4
본 논문의 목적은 군 정비 프로세스를 평가하기 위해 장비 운용가용도를 핵심 성과지표로 한 평가 모형을 구축하고, 정비 프로세스 향상에 미치는 영향요인을 파악하는 것이다. 군의 전투준비태세 완비 여부는 장비 운용가용도와 직결되기 때문에 목표 운용가용도를 유지하기 위한 효율적인 정비활동이 요구된다. 따라서 장비 운용개념, 정비 및 수리부속 정책, 장비 운용가용도의 직접적 원인이 되는 장비 불가동시간을 복합적으로 고려하여 일반화된 정비 프로세스를 모델링하였다. 또한, 시뮬레이션을 이용하여 일반화된 정비 프로세스에 대한 평가 모형을 구축한 후, 운용가용도를 측정하고 운용가용도 변화의 영향요인을 분석하였다. 본 연구는 정비 프로세스를 일반화하고 평가 모형을 구축함으로써, 이를 기반으로 정비 프로세스 향상 방안을 도출할 수 있다는데 의의가 있다. The purposes of this study are twofold: to construct a generalized model for assessing the operational availability and the target availability achievement rate of military maintenance processes, and to identify the major factors affecting the operational availability of maintenance processes. Downtime has a direct impact on operational availability. Downtime is divided into three categories: ADT (Administrative Delay Time), LDT (Logistics Delay Time), and maintenance time due to the maintenance capability restrictions. Based on the analyses of such downtimes and maintenance policies and regulations, this paper proposes a maintenance process model from bases to depots. For the assessment of maintenance processes, a simulation method is adopted. In the empirical study, a UH-60 helicopter was chosen because it is operated in every military service. Using such simulation model, sensitivity analysis was performed on the operational availability depending on the changes in the maintenance factors: capability, spare parts stock levels, order period, and transport time. The operational availability changes depending on the aforementioned factors. In this study, the major factors influencing the improvement of the operational availability were identified, and the maintenance capability was determined to be the most important of such factors. Maintenance systems vary depending on the military service and weapon system. The results of this study can be applied to weapon systems to identify the factors that restrict the improvement of the operational availability.
자울약침액(紫菀藥鍼液)의 폐유(肺兪) 처치(處置)가 Type I Hypersensitivity에 미치는 영향
권혁상,송춘호,Kwon, Hyuk-Sang,Song, Choon-Ho 대한침구의학회 2006 대한침구의학회지 Vol.23 No.5
Objectives : We studied the effects of Radix Asteris herbal acupuncture solution (RAHAS) on the type I hypersensitivity. Methods : In vivo, we measured compound 48/80 induced active systemic anaphylactic shock, anti-DNP IgE induced passive cutaneous anaphylaxis (PCA) and acetic acid induced microvascular permeability using ICR mice. In vitro, we showed effects on cytotoxicity and ${\beta}$-hexosaminidase release from RBL-2H3 cells. Results : In vivo, RAHAS pretreatments at $BL_{13}$ and optional points inhibited active systemic anaphylactic shock induced by compound 48/80 and microvascular permeability increased by acetic acid. PCA was only inhibited by RAHAS pretreatments at $BL_{13}$. In vitro, RAHAS treatments inhibited ${\beta}$-hexosaminidase release. Conclusion : These results suggest that RAHAS may be beneficial in the prevention of type I hypersensitive inflammatory response.