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강희인,김영수,고용,오성훈,오석전,김남규,김광명,이승로,함창곡,홍은경 대한신경외과학회 1994 Journal of Korean neurosurgical society Vol.23 No.5
The histopathologic findings of the intracranial meningioma are variegated and those of magnetic resonance imaging (MRI) which has been used for preoperative evaluation are also vaned in signal characteristics. In order to aid the preoperative diagnosis, authors analyzed MRI and microscopic findings in twenty eight meningioma cases which underwent surgery. The results were summarized as follows: 1) Meningothelial, fibrous and transitional subtypes showed isointense signal on T1-weighted image and iso and/or hyperintense signal on T2-weighted and proton density images compared to the signal intensity of the gray matter. 2) Microcystic subtype was isointense signal on T1-weighted image and hyperintense Signal on T2-weighted and proton density images. 3) Variation of signal intensity might be correlated to the ratio of the stroma in the tumor. 4) Peritumoral edema was not closely related to the pathologic subtypes or location of meningioma, but it seemed to be correlated with the sue of tumor.
강희인,이원학,오해수,김동석,김상중,Kang, Hee-In,Lee, Won-Hak,Oh, Hae-Soo,Kim, Dong-Suk,Kim, Sang-Joong 대한악안면성형재건외과학회 2005 Maxillofacial Plastic Reconstructive Surgery Vol.27 No.6
Keratoacanthoma is a benign, self-limited epithelial lesion that closely resembles Squamous cell carcinoma(SCC). Keratoacanthoma occur primarily exposed skin in male patients over 45 years of ages. although etiology is unknown, sunlight, genetic, and human papillomavirus factor have been considered. in clinical feature, rapid enlargement occurs over 4$\sim$8 weeks, resulting ultimately in a hemispheric, firm, elevated, asymptomatic nodule that contains a central plug of keratin. When fully developed, the keratoacanthoma contains a core of keratin surrounded by a concentric collar of raised skin. Over the next 4$\sim$8 weeks, static lesion persists. Then undergoes spontaneous regression over the next 6$\sim$8weeks period by expulsion of the keratin core with resorption of the mass. In histologic feature, Keratoacanthoma consists of hyperplastic squamous epithelium growing into the underlying connective tissue. The surface is covered by a thickened layer of parakeratin with central plugging. Epithelium cell shows dysplastic features and the margins the normal adjacent epithelium is elevated. The differential diagnosis includes SCC. Keratoacanthoma present as a exophytic lesion with horny keratin occupying a depression on the top of the lesion, persists static period and undergoes rapid growth compared with SCC. Keratoacanthoma is usually treated by surgical excision or curettage of the base, spontaneous regression does not occur in every case. A 60 years old male who present facial lesion visit our hospital and surgical excision was done. Biopsy result was keratoacanthoma. We report case with review of literatures.