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고원진 ( Weon Jin Ko ),이병무 ( Byoung Moo Lee ),박원영 ( Won Young Park ),김진녕 ( Jin Nyoung Kim ),조준형 ( Jun Hyung Cho ),이태희 ( Tae Hee Lee ),홍수진 ( Su Jin Hong ),조주영 ( Joo Young Cho ) 대한소화기학회 2014 대한소화기학회지 Vol.64 No.6
A 49-year-old woman visited our hospital with dysphagia and chest pain. In another hospital, she was diagnosed as reflux esophagitis. Although she had taken proton pump inhibitor and prokinetics drugs for a long time, she was not relieved of any symptoms. On the basis of high resolution manometry and endoscopic ultrasonography findings, Jackhammer esophagus was diagnosed. In this patient, peroral endoscopic myotomy (POEM) was performed for long myotomy of thickened circular muscle. During the procedure, there were no significant complications and she was discharged uneventfully. Symptoms were completely improved during three months after POEM. Here, we report on a case of Jackhammer esophagus treated by POEM. (Korean J Gastroenterol 2014;64:370-374)
고원배 ( Weon Bae Ko ),권석찬 ( Sock Chan Kown ),정홍식 ( Hong Seok Jeong ) 한국고무학회 2003 엘라스토머 및 콤포지트 Vol.38 No.2
풀러렌[C_60, C_70]을 benzoylperoxide, trichloroisocyanuric acid, methyltrioxorhenium(Ⅶ), iodosobenzene 그리고 phosphorous pentoxide 등의 산화제를 사용하여 상온, 초음파 조건에서 풀러렌 산화물을 제조하였다. MALDI-TOF MS, UV-VIS 그리고 HPLC를 사용하여 분석한 결과 생성된 풀러렌 산화물은 [C_60(O)_n](n=1~3, 또는 n=1) 과 [C_70(O)_n](n=1~2 또는 n=1)임을 알 수 있었다. 한편, 동일한 실험 조건에서 C_60 반응속도는 C_70보다 높았다. Synthesis of fullerene oxides by fullerenes [C_60, C_70] and several oxidants such as benzoylperoxide, trichloroisocyanuric acid, methyltrioxorhenium(Ⅶ), iodosobenzene, phosphorous pentoxide take place under ultrasonic condition at room temperature. The MALDI-TOF MS,UV-visible spectra and HPLC analysis confirmed that the products of fullerenes oxidation are [C_60(O)_n], (n=1~3 or n=1) and [C_70(O)_n], (n=1~2 or n=1). As compared with the reactivity of epoxidation of fullerenes [C_60, C_70], the reaction rate of C_70 was lower than that of C_60 under same reaction condition.