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강영우,박봉기,이상숙,송홍석,박재후,서승연 대한내과학회 1987 대한내과학회지 Vol.33 No.1
Herein we reported a case of sinus histiocytosis with massive lymphadenopathy which was the second in our nation. The patient was 53-year old man with a ten-year clinical course of SHML. Since three years before admission, he was suffered from generalized lymphadenopathy, nasal stuffiness, and multiple dark-reddish colored skin papules. Since 1 month before admission, more progression of nasal stuffiness and lymph node enlargement with persistent frontal headache were developed. Microscopic examination of cervical lymph node and skin tissues revealed characteristic features of SHML: predominant histiocyte infiltration, lymphophagocytosis, plasma cell proliferation. Laboratory examination disclosed anemia, increased erythrocyte sedimentation rate, polyclonal gammopathy and CSF protein of 434 mg/dl with WBC of 63/mm³. We observed a defect in cellular immune function, cutaneous anergy by Multi-CMI skin test. After treatment with vinblastine and prednisolone, improvement of headache, nasal stuffiness, and lymph node enlargement were noted.
운동장애성 소화불량 환자에서 물 섭취가 포만감과 위전도에 미치는 영향
강영우,손수상,박승국,황재석,장병국 대한소화기학회 1999 대한소화기학회지 Vol.33 No.4
Background/Aims: The aim of this study was to evaluate the influence of water ingestion on electrogastrographic findings and epigastric fullness in patients with dysmotility-like functional dyspepsia (DLFD). Methods: The study was performed on 15 patients with DLFD and 17 normal controls Abdominal surface electrogastrography was applied for 30 min in fasting state and for 30 min afte water ingestion to bring epigastric fullness. Results: Patients with DLFD showed higher scale of epigastric fullness in fasting, postprandial 20 min and postprandial 30 min, compared with norma controls. There was no difference between the patients and controls in the amount of ingested wate which brought epigastric fullness. Significant differences were found in the percentage of fed 3 cpm wave and the percentage of fed bradygastria. No significant differences were found in the percentage of fed tachygastria, fasting electrogastrographic findings and power ratio. No correlation was found between the percentage of 3 cpm slow wave and the scale of epigastric fullness. Conclusions: Pati ents with DLFD showed higher percentage of 3 cpm wave after ingestion of water. The amount o ingested water to bring epigastric fullness was similar in the patients and normal controls.
기능성 소화불량환자에서 체감각 , 뇌간청각 및 시각 유발전위
강영우,한승엽,임정근 대한소화기학회 1997 대한소화기학회지 Vol.29 No.6
Background/Aims: Although gastrointestinal dysmotility have played an important role in pathophysiology of functional dyspepsia, visceral perception abnormalities due to visceral hypersensitivity are now thought to be a major pathophysiologic mechanism of functional dyspepsia. Visceral hypersensitivity occurred at both visceral afferent pathway and autonomic regulation of central system. The present study was performed to evaluate the possible role of abnormal central perception in the pathophysiology of functional dyspepsia by using various evoked potentials. Methods: The study population consisted of 22 patients with functional dyspepsia and 22 healthy volunteers attending Keimyung University hospital from June 1995 to December 1995. They were studied somaiosensory evoked potentials(SSEP), brainstem auditory evoked potentials(BAEP) and visual evoked potentials(VEP) and compared the absolute latencies, interpeak latencies and amplitudes of each evoked potential between two groups. Results: There were no significant differences in absolute latencies of EP, N13, N19 and P22 waves and amplitudes of EP, N13 and N19/P22 at SSEP between functional dyspepsia and norrnal control. There were no significant differences in absolute latencies of I, II, III, IV and V waves, and interpeak latencies of I -III, m- V and I V at BAEP between functional dyspepsia and normal control. There were no significant differences in absolute latencies and amplitudes of P100 at VEP between functional dyspepsia and normal control. Conclusions: The present study could not reveal abnormal central percepition by using somatosensory, auditory and visual evoked potentials in patients with functional dyspepsia.
허정욱,이수형,안성훈,박승국,천종욱,강영우 啓明大學校 醫科大學 1987 계명의대학술지 Vol.6 No.2
Clinical analysis was performed on 1582 cases of peptic ulcer patients who were diagnosed by gastrofiberscopy at DONG SAN MEDICAL CENTER during past 5 years from 1982 to 1986. We analyzed them is terms of incidence of peptic ulcer, the ratio of grastric ulcer to duodenal ulcer, age and sex distribution, and the sites of gastric ulcer. We have got the following results. 1) We observed 1528 cases of peptic ulcer of which duodenal ulcer comprised 802 cases(52.5%) and gastric ulcer 726 cases(47.5%). 2) Annual incidence of peptic ulcer disease was variable. 3) As to the gastric ulcer, 642 cases(88.4%) were developed above 35 by age, but only 84 cases(11.6%) were developed below 35. 4) About the sites of gastric ulcer, antrum was more commonly involved than body below 60 by age. but in cases of above 60, body was more commonly involved(p<0.05). 5) The sex ratio )male: female)of gastric ulcer was 3.4:1 but in female, gastric ulcer occurred in older age group than in male(p<0.01). 6) In pediatric field, the incidence of duodenal ulcer was 3.4 times greater than that of gastric ulcer.