Experimental investigation of impact of addition of bioethanol in different biodiesels, on performance, combustion and emission characteristics

Mehmet Çelik,İlker Örs,Cihan Bayindirli,Mehmet Demiralp 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.11

This study includes the experimental evaluation of performance, combustion and emission characteristics of cottonseed and grapeseed biodiesels and blends containing bioethanol in a diesel engine with different engine speeds at full load. Addition of bioethanol into the fuels (diesel and biodiesel) used by diesel engines is considered an effective solution. The study observed that the cetane number, viscosity, density and lower heating value of fuel were reduced after the addition of bioethanol in all engine speeds. While the brake power and torque values were reduced as the rate of bioethanol increased, additionally specific fuel consumption, maximum cylinder pressure, heat release and ignition delay also increased. Reviewing the emission results, carbon monoxide (CO) and total hydrocarbon (THC) emissions increased as bioethanol rate increased, nitrogen oxides (NO x ) and smoke emissions were reduced.

Changes in Pre- and Post-Electroconvulsive Therapy Serum Myostatin Levels in Patients with Treatment Resistant Depression

Cemil Çelik,Abdullah Bolu,Taner Öznur,Mehmet Sinan Aydın,Yusuf Tokgöz,Özcan Uzun 대한정신약물학회 2019 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.17 No.1

Objective: Myostatin is a growth factor which is investigated regarding musculoskeletal system. Albeit its effect on muscle mass is known, it is considered likely having other unknown effects as well, particularly on central nervous system. With this study, it is aimed to find out that what type of effect electroconvulsive therapy (ECT) does on myostatin in patients with treatment resistant depression. Methods: Twenty-nine patients with treatment resistant major depression and thirty healthy volunteers were included in the study. Pre- and post-ECT levels of myostatine were compared; also this results were compared to healthy controls. Results: For 29 patients with treatment-resistant major depression, the pre-treatment mean myostatin level was 0.95±0.32 ng/ml and post-therapy myostatin level was 11.05±6.97 ng/ml. As a result of this study, it is found that ECT affects serum myostatin levels to a significant degree (t=4.17, p<0.05). It is also found that there was a significant relation between serum myostatin levels and depression scores (r=0.392, p<0.05). Conclusion: With the present study and similar ones, it can be understood that how ECT achieves its effectiveness biologically.

Serum Levels of High Sensitivity C-reactive Protein in Drug-naïve First-episode Psychosis and Acute Exacerbation of Schizophrenia

Abdullah Bolu,Mehmet Sinan Aydın,Abdullah Akgün,Ali Coşkun,Beyazıt Garip,Taner Öznur,Cemil Çelik,Özcan Uzun 대한정신약물학회 2019 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.17 No.2

Objective: Findings about inflammatory processes in schizophrenia are increasing day by day. Inflammatory processes in schizophrenia are associated with both its etiology and clinical symptoms. Serum high-sensitivity C-reactive protein (hsCRP) is also one of these inflammatory processes. Particularly, it is thought to be closely related to clinical findings of patients with schizophrenia. Methods: In this study, the relationship between clinical findings of hsCRP levels of patients with drug-naïve first-episode psychosis (FEP) and patients with schizophrenia in acute exacerbation phase is investigated. Clinical findings, psychometric properties (the Scale for the Assessment of Positive Symptoms, the Scale for the Assessment of Negative Symptoms, Brief Psychiatric Rating Scale), and hsCRP levels of patients were compared. Results: Forty-eight patients with FEP, 74 patients with schizophrenia in acute exacerbation phase and 54 healthy controlled volunteers are included in the study. The most substantial finding in the study is that there is a positive correlation between hsCRP levels and severity of positive symptoms of both patient groups, with FEP and with schizophrenia. The second most substantial finding is there is no significant difference between patients with FEP and schizophrenia, in terms of hsCRP. Conclusion: The relationship between hsCRP and positive symptom severity in two groups of patients supports the inflammatory hypothesis in the etiopathogenesis of schizophrenia. This finding is supportive of close relation between inflammatory processes and clinical findings of patient with schizophrenia.

Assessment of Proportion of Hidden Patients Having Symptoms of Overactive Bladder and Why Has It Been Hidden in Female Outpatients Admitted to Hospital

Oktay Üçer,Ömer Demir,Mehmet Fatih Zeren,Yasin Ceylan,İlker Çelen,Ali Ersin Zümrütbaş,Gökhan Temeltaş,Ozan Bozkurt,Bülent Günlüsoy,Orçun Çelik,Gökhan Ekin,Oğuz Mertoğlu,Aegean Study Group of Society o 대한배뇨장애요실금학회 2016 International Neurourology Journal Vol.20 No.1

Purpose: To determine the proportion of patients with undetected symptoms of overactive bladder by using the overactive bladder-validated 8 (OAB-V8) screening questionnaire and investigate these symptoms were undetected in female patients who were hospitalized. Methods: We invited 2,250 female patients hospitalized in the Aegean region of Turkey to answer a self-administered questionnaire. The questionnaire included questions on evidence of lower urinary tract symptoms (OAB-V8), relevant medical history, and demographic data. Patients with a total OAB-V8 score≥8 were defined as having OAB symptoms. Results: The proportion of patients with OAB symptoms in this study was 40.6%. Nearly 57% of the patients with OAB symptoms had not been previously admitted to any hospital for lower urinary tract symptoms (LUTS). The two most common reasons why women with OAB symptoms did not admit themselves to a hospital because of LUTS were as follows: “I did not think I had a disease” and “The symptoms did not bother me,” with a response rate of 74.7%. The mean OAB-V8 scores of the patients with these two responses were significantly lower than those of the other patients (P<0.001). Conclusions: This is the first study to demonstrate a significant proportion of women with undetected OAB symptoms. The main reasons the women did not admit themselves to a hospital were their unawareness of the disease and because the LUTS were not bothersome. Public awareness programs on this disease may resolve this problem.

Explanation of difenoconazole removal by chitosan with Langmuir adsorption isotherm and kinetic modeling

Altun Şükran,Kadak Ali Eslem,Küçükgülmez Aygül,Gülnaz Osman,Çelik Mehmet 한국독성학회 2023 Toxicological Research Vol.39 No.1

In this study, the adsorption of toxic difenoconazole pesticide was investigated by using chitosan. In the first phase of the study, chitosan was extracted from deep-water pink shrimp (Parapenaeus longirostris) shells, by deacetylation of the chitin, which is separated and disposed of after meat extraction in processing facilities in Turkey. The deacetylation degree, molecular weight, viscosity, moisture, and crude-ash values of the extracted chitosan were determined. Chitosan, having a high deacetylation degree (90.21%), was used as the adsorbent. In the second phase of the study, the effects of pH, temperature, and pesticide concentration on the adsorption were investigated. The optimum pH level for pesticide adsorption was determined as 5. It was observed that the adsorption increases as the temperature increases. A rapid increase was observed within the first 5 min of the 60-minute adsorption process in difenoconazole concentrations of 5, 15, and 25 μg/L, and after 10 min, the adsorption rate was stable. The Langmuir isotherm parameters regarding the adsorption were determined as aL = 0.635, kL = 15.10, and the Qmax value was calculated as 23.77 mg/g. In the evaluation of overall study results, it was determined that the chitosan biopolymer is a suitable adsorbent for difenoconazole pesticide adsorption.

Validity and Reliability of Cognitive Attentional Syndrome-1 Questionnaire

Anıl Gü,ndü,z,İ,brahim Gü,ndoğ,muş,Sencan Sertç,elik,Betü,l Hacer Engin,Aysel İ,ş,ler,Arif Ç,ipil,Hatice Gö,nü,l,Aliş,an Burak Yaş,ar,Mehmet 대한신경정신의학회 2019 PSYCHIATRY INVESTIGATION Vol.16 No.5

Objective: This study aimed to evaluate the reliability and validity of the Turkish version of Cognitive Attentional Syndrome-1 (CAS-1) questionnaire. Methods: 221 participants were included in the study who do not meet any psychiatric diagnosis. Participants were applied SCID I and II and filled CAS-1 scale, Meta-Cognitions Questionnaire-30 (MCQ-30), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Generalized Anxiety Disorder-7 (GAD-7) Scale, and Penn State Worry Questionnaire (PSWQ). Testing the reliability Cronbach’s alpha, item analysis and Item and total score correlation coefficients were applied. For testing structural validity, Confirmatory Factor Analysis was used, and for testing the content validity, the relationship between each item of CAS-1 and MCQ-30, BDI, BAI, GAD-7, PSWQ was examined. Results: The correlation reliability coefficients were statistically significant except for using alcohol/drugs as a coping mechanism. Cronbach Alpha reliability coefficient of 16 items was 0.771 whereas, this ratio was 0.772 for the first eight items (CAS) and 0.685 for the last eight items (Metacognitive Beliefs) which showed that the internal consistency of CAS-1 was high. Structural and Content Validity of the scale was significant. Conclusion: The Turkish version of the CAS-1 was a reliable and valid measure to evaluate CAS in a Turkish population.