Effects of aspect ratio on laboratory simulation of tornado-like vortices

Tang, Zhuo,Zuo, Delong,James, Darryl,Eguch, Yuzuru,Hattori, Yasuo Techno-Press 2018 Wind and Structures, An International Journal (WAS Vol.27 No.2

Experiments were conducted in a large-scale Ward-type tornado simulator to study tornado-like vortices. Both flow velocities and the pressures at the surface beneath the vortices were measured. An interpretation of these measurements enabled an assessment of the mean flow field as well as the mean and fluctuating characteristics of the surface pressure deficit, which is a manifestation of the flow fluctuation aloft. An emphasis was placed on the effect of the aspect ratio of the tornado simulator on the characteristics of the simulated flow and the corresponding surface pressure deficit, especially the evolution of these characteristics due to the transition of the flow from a single-celled vortex to a two-celled vortex with increasing swirl ratio.

Effects of aspect ratio on laboratory simulation of tornado-like vortices

Zhuo Tang,Delong Zuo,Darryl James,Yuzuru Eguchi,Yasuo Hattori 한국풍공학회 2018 Wind and Structures, An International Journal (WAS Vol.27 No.2

Experiments were conducted in a large-scale Ward-type tornado simulator to study tornado-like vortices. Both flow velocities and the pressures at the surface beneath the vortices were measured. An interpretation of these measurements enabled an assessment of the mean flow field as well as the mean and fluctuating characteristics of the surface pressure deficit, which is a manifestation of the flow fluctuation aloft. An emphasis was placed on the effect of the aspect ratio of the tornado simulator on the characteristics of the simulated flow and the corresponding surface pressure deficit, especially the evolution of these characteristics due to the transition of the flow from a single-celled vortex to a two-celled vortex with increasing swirl ratio.

Identifying Differentially Expressed Genes and Screening Small Molecule Drugs for Lapatinib-resistance of Breast Cancer by a Bioinformatics Strategy

Zhuo, Wen-Lei,Zhang, Liang,Xie, Qi-Chao,Zhu, Bo,Chen, Zheng-Tang Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.24

Background: Lapatinib, a dual tyrosine kinase inhibitor that interrupts the epidermal growth factor receptor (EGFR) and HER2/neu pathways, has been indicated to have significant efficacy in treating HER2-positive breast cancer. However, acquired drug resistance has become a very serious clinical problem that hampers the use of this agent. In this study, we aimed to screen small molecule drugs that might reverse lapatinib-resistance of breast cancer by exploring differentially expressed genes (DEGs) via a bioinformatics method. Materials and Methods: We downloaded the gene expression profile of BT474-J4 (acquired lapatinib-resistant) and BT474 (lapatinib-sensitive) cell lines from the Gene Expression Omnibus (GEO) database and selected differentially expressed genes (DEGs) using dChip software. Then, gene ontology and pathway enrichment analyses were performed with the DAVID database. Finally, a connectivity map was utilized for predicting potential chemicals that reverse lapatinib-resistance. Results: A total of 1, 657 DEGs were obtained. These DEGs were enriched in 10 pathways, including cell cycling, regulation of actin cytoskeleton and focal adhesion associate examples. In addition, several small molecules were screened as the potential therapeutic agents capable of overcoming lapatinib-resistance. Conclusions: The results of our analysis provided a novel strategy for investigating the mechanism of lapatinib-resistance and identifying potential small molecule drugs for breast cancer treatment.

Thermodynamic simulation and structural optimization of the collimator in the drift duct of EAST-NBI

Tang Ning,Hu Chun-dong,Xie Yuan-lai,Wei Jiang-long,Cui Zhi-Wei,Xie Jun-Wei,Pan Zhuo,Jiang Yao 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.11

The collimator is one of the high-heat-flux components used to avoid a series of vacuum and thermal problems. In this paper, the heat load distribution throughout the collimator is first calculated through experimental data, and a transient thermodynamic simulation analysis of the original model is carried out. The error of the pipe outlet temperature between the simulated and experimental values is 1.632%, indicating that the simulation result is reliable. Second, the model is optimized to improve the heat transfer performance of the collimator, including the contact mode between the pipe and the flange, the pipe material and the addition of a twisted tape in the pipe. It is concluded that the convective heat transfer coefficient of the optimized model is increased by 15.381% and the maximum wall temperature is reduced by 16.415%; thus, the heat transfer capacity of the optimized model is effectively improved. Third, to adapt the long-pulse steady-state operation of the experimental advanced superconducting Tokamak (EAST) in the future, steady-state simulations of the original and optimized collimators are carried out. The results show that the maximum temperature of the optimized model is reduced by 37.864% compared with that of the original model. The optimized model was changed as little as possible to obtain a better heat exchange structure on the premise of ensuring the consumption of the same mass flow rate of water so that the collimator can adapt to operational environments with higher heat fluxes and long pulses in the future. These research methods also provide a reference for the future design of components under high-energy and long-pulse operational conditions

Molecular Cloning and Characterization of the Yew Gene Encoding Squalene Synthase from Taxus cuspidata

( Zhuo Shi Huang ),( Ke Ji Jiang ),( Yan Pi ),( Rong Hou ),( Zhi Hua Liao ),( Ying Cao ),( Xu Han ),( Qian Wang ),( Xiao Fen Sun ),( Ke Xuan Tang ) 생화학분자생물학회 2007 BMB Reports Vol.40 No.5

Application of SA-SVM Incremental Algorithm in GIS PD Pattern Recognition

Tang, Ju,Zhuo, Ran,Wang, DiBo,Wu, JianRong,Zhang, XiaoXing The Korean Institute of Electrical Engineers 2016 Journal of Electrical Engineering & Technology Vol.11 No.1

With changes in insulated defects, the environment, and so on, new partial discharge (PD) data are highly different from the original samples. It leads to a decrease in on-line recognition rate. The UHF signal and pulse current signal of four kinds of typical artificial defect models in gas insulated switchgear (GIS) are obtained simultaneously by experiment. The relationship map of ultra-high frequency (UHF) cumulative energy and its corresponding apparent discharge of four kinds of typical artificial defect models are plotted. UHF cumulative energy and its corresponding apparent discharge are used as inputs. The support vector machine (SVM) incremental method is constructed. Examples show that the PD SVM incremental method based on simulated annealing (SA) effectively speeds up the data update rate and improves the adaptability of the classifier compared with the original method, in that the total sample is constituted by the old and new data. The PD SVM incremental method is a better pattern recognition technology for PD on-line monitoring.

A Method of Chinese and Thai Cross-Lingual Query Expansion Based on Comparable Corpus

Tang, Peili,Zhao, Jing,Yu, Zhengtao,Wang, Zhuo,Xian, Yantuan Korea Information Processing Society 2017 Journal of information processing systems Vol.13 No.4

Cross-lingual query expansion is usually based on the relationship among monolingual words. Bilingual comparable corpus contains relationships among bilingual words. Therefore, this paper proposes a method based on these relationships to conduct query expansion. First, the word vectors which characterize the bilingual words are trained using Chinese and Thai bilingual comparable corpus. Then, the correlation between Chinese query words and Thai words are computed based on these word vectors, followed with selecting the Thai candidate expansion terms via the correlative value. Then, multi-group Thai query expansion sentences are built by the Thai candidate expansion words based on Chinese query sentence. Finally, we can get the optimal sentence using the Chinese and Thai query expansion method, and perform the Thai query expansion. Experiment results show that the cross-lingual query expansion method we proposed can effectively improve the accuracy of Chinese and Thai cross-language information retrieval.

A Method of Chinese and Thai Cross-Lingual Query Expansion Based on Comparable Corpus

( Peili Tang ),( Jing Zhao ),( Zhengtao Yu ),( Zhuo Wang ),( Yantuan Xian ) 한국정보처리학회 2017 Journal of information processing systems Vol.13 No.4

Cross-lingual query expansion is usually based on the relationship among monolingual words. Bilingual comparable corpus contains relationships among bilingual words. Therefore, this paper proposes a method based on these relationships to conduct query expansion. First, the word vectors which characterize the bilingual words are trained using Chinese and Thai bilingual comparable corpus. Then, the correlation between Chinese query words and Thai words are computed based on these word vectors, followed with selecting the Thai candidate expansion terms via the correlative value. Then, multi-group Thai query expansion sentences are built by the Thai candidate expansion words based on Chinese query sentence. Finally, we can get the optimal sentence using the Chinese and Thai query expansion method, and perform the Thai query expansion. Experiment results show that the cross-lingual query expansion method we proposed can effectively improve the accuracy of Chinese and Thai cross-language information retrieval.

A review of source tracking techniques for fine sediment within a catchment

Guan, Zhuo,Tang, Xiang-Yu,Yang, Jae E.,Ok, Yong Sik,Xu, Zhihong,Nishimura, Taku,Reid, Brian J. Springer-Verlag 2017 Environmental geochemistry and health Vol.39 No.6

<P>Excessive transport of fine sediment, and its associated pollutants, can cause detrimental impacts in aquatic environments. It is therefore important to perform accurate sediment source apportionment to identify hot spots of soil erosion. Various tracers have been adopted, often in combination, to identify sediment source type and its spatial origin; these include fallout radionuclides, geochemical tracers, mineral magnetic properties and bulk and compound-specific stable isotopes. In this review, the applicability of these techniques to particular settings and their advantages and limitations are reviewed. By synthesizing existing approaches, that make use of multiple tracers in combination with measured changes of channel geomorphological attributes, an integrated analysis of tracer profiles in deposited sediments in lakes and reservoirs can be made. Through a multi-scale approach for fine sediment tracking, temporal changes in soil erosion and sediment load can be reconstructed and the consequences of changing catchment practices evaluated. We recommend that long-term, as well as short-term, monitoring of riverine fine sediment and corresponding surface and subsurface sources at nested sites within a catchment are essential. Such monitoring will inform the development and validation of models for predicting dynamics of fine sediment transport as a function of hydro-climatic and geomorphological controls. We highlight that the need for monitoring is particularly important for hilly catchments with complex and changing land use. We recommend that research should be prioritized for sloping farmland-dominated catchments.</P>

Application of SA-SVM Incremental Algorithm in GIS PD Pattern Recognition

Ju Tang,Ran Zhuo,DiBo Wang,JianRong Wu,XiaoXing Zhang 대한전기학회 2016 Journal of Electrical Engineering & Technology Vol.11 No.1

With changes in insulated defects, the environment, and so on, new partial discharge (PD) data are highly different from the original samples. It leads to a decrease in on-line recognition rate. The UHF signal and pulse current signal of four kinds of typical artificial defect models in gas insulated switchgear (GIS) are obtained simultaneously by experiment. The relationship map of ultrahigh frequency (UHF) cumulative energy and its corresponding apparent discharge of four kinds of typical artificial defect models are plotted. UHF cumulative energy and its corresponding apparent discharge are used as inputs. The support vector machine (SVM) incremental method is constructed. Examples show that the PD SVM incremental method based on simulated annealing (SA) effectively speeds up the data update rate and improves the adaptability of the classifier compared with the original method, in that the total sample is constituted by the old and new data. The PD SVM incremental method is a better pattern recognition technology for PD on-line monitoring.