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RISS 인기검색어
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- 저자 : ( Xueliang Yang ) (검색결과 5 건)
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HCBP6 upregulates human SREBP1c expression by binding to C/EBPβ-binding site in the SREBP1c promoter
( Xueliang Yang ),( Ming Han ),( Shunai Liu ),( Xiaoxue Yuan ),( Xiaojing Liu ),( Shenghu Feng ),( Li Zhou ),( Yaru Li ),( Hongping Lu ),( Jun Cheng ),( Shumei Lin ) 생화학분자생물학회(구 한국생화학분자생물학회) 2018 BMB Reports Vol.51 No.1
Sterol regulatory element-binding protein-1c (SREBP1c) plays an important role in triglyceride (TG) homeostasis. Although our previous study showed that hepatitis C virus core-binding protein 6 (HCBP6) regulates SREBP1c expression to maintain intracellular TG homeostasis, the mechanism underlying this regulation is unclear. In the present study, we found that HCBP6 increased intracellular TG levels by upregulating SREBP1c expression. HCBP6 increased SREBP1c transcription by directly binding to the SREBP1c promoter (at the -139- to +359-bp region). Moreover, we observed that HCBP6 interacted with C/EBPβ-binding site in the SREBP1c promoter both in vitro and in vivo. These results indicate that HCBP6 upregulates human SREBP1c expression by binding to the C/EBPβ-binding site in the SREBP1c promoter. [BMB Reports 2018; 51(1): 33-38]
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Preparation and Electrochemical Application of Porous Yttrium-Doped NiO Microspheres
Xueliang Jiang,Chenjian Li,Yanrong Gao,Canyu Yang,Feng You,Chu Yao 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2018 NANO Vol.13 No.2
Using NiCl2 · 6H2O and Y(NO)3 solution as raw material and urea as the precipitating agent, Yttrium-doped NiO hollow spheres (Y-NiOHS) were prepared through homogeneous precipitation method with melamine–formaldehyde polymer microspheres (MF) as templates. The electrochemical performances of Y-NiOHS with difference Y-doped mole ratios (Y : Ni = 0.3%, 0.5%, 1% Y-NiOHS) were characterized by cyclic voltammetry (CV), constant current charge–discharge test (GCD) and AC impedance test (EIS). The results of CV show that 0.5% Y-NiOHS in 5 mV/s scan rate can achieve the maximum capacity of 320.92 F/g. The results of GCD show that the capacity of 0.5%Y-NiOHS is 226.2 F/g at 0.5 A/g discharge current density and the 1000 charge–discharge cycles after the capacitance retention rate is 85%. The electrochemical performance of 0.5%Y-NiOHS are better than NiOHS and NiO powder.
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Design and optimization of novel transceiver device for one‑way single‑wire power transfer
Yang Li,Taocheng Hu,Xueliang Wang,Yujie Zhai,Yao Li,Wenxin Huang,Zhigang Lou 전력전자학회 2023 JOURNAL OF POWER ELECTRONICS Vol.23 No.10
The further development of wireless power transfer technology is hindered by the limiting relationship between transmission distance, transmission efficiency, and size of the coupling mechanism. Thus, a feasible solution was provided by one-way single-wire power transfer. First, a horn-type mode conversion device was proposed in this study by analyzing the principle of one-way single-wire power transfer. Second, the system structure was designed to save materials and reduce the volume of space. The transmission efficiency of the system was improved, and the operating frequency was reduced by optimizing the parameters of the mode conversion device. Finally, the feasibility and structural applicability of the one-way single-wire power transfer method proposed in this study were proved by the experimental results.
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DFT study of the oxidation of Hg0 by O2 on an Mn-doped buckled g-C3N4 catalyst
Liu Shuai,Xu Mengxia,Chen Yipei,Mu Xueliang,Yu Jiahui,Yang Gang,Luo Xiang,Jiang Peng,Wu Tao 한국물리학회 2022 Current Applied Physics Vol.40 No.-
Due to the water-insoluble nature of Hg0, its oxidization to Hg2+, which is water-soluble, is a viable approach for its effective removal at coal-fired plants using existing flue gas desulfurization (FGD) unit. In this study, the adsorption and oxidation of elemental mercury on an Mn-doped g-C3N4 material were investigated. The spinpolarized density functional theory method was adapted to optimize the geometry structures and then to determine the corresponding electronic structures, while the CI-NEB method was adopted to search for the stable intermediates during the reaction(s). The analysis of energy and project density of states shows that the Mn-g- C3N4 exhibits an excellent affinity to Hg atoms. It is found that it is feasible for Hg atoms to oxidize on the Mn-g- C3N4 surface via two possible E-R paths, but with relatively high energy barriers. This research provides insights into a viable way for mercury removal using O2 as the oxidizing agent.
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Zhang Aiqing,Liu Wenjuan,Niu Lingyun,Zhu Liping,Yang Liuqing,Li Xueliang 한국유전학회 2023 Genes & Genomics Vol.45 No.5
Background Gastroesophageal reflux disease (GERD) is a highly prevalent and troublesome disease. Several differentially expressed microRNAs (miRNAs) have been found in GERD. Objective This study was to analyze the correlation of miR-29a-3p expression and CYP2C19 genotypes in exfoliated cells from tongue coating of GERD patients and its prognostic value. Methods Tongue coating specimens were collected from 130 GERD patients and 70 healthy volunteers and their clinical baseline information was recorded. miR-29a-3p expression in exfoliated cells from tongue coating was determined via RT-qPCR, and its diagnostic efficiency on GERD was evaluated via receiver operating characteristic curve. CYP2C19 genotypes and their correlation with miR-29a-3p were analyzed via polymerase chain reaction restriction fragment length polymorphism technique. The adverse events of patients were documented via 12-month follow-up. The impact of miR-29a-3p expression on the healing rate of patients was analyzed via Kaplan-Meier method. Qualification of miR-29a-3p as an independent prognostic factor of GERD patients was analyzed via multivariate Cox regression analysis. Results miR-29a-3p was highly-expressed in exfoliated cells from tongue coating of GERD patients. miR-29a-3p expression had high specificity and sensitivity in diagnosing GERD. CYP2C19 genotypes in GERD patients comprised rapid metabolizers, intermedia metabolizers, and poor metabolizers. miR-29a-3p expression showed a correlation with CYP2C19 genotypes. Higher miR-29a-3p expression predicted higher cumulative incidences of adverse outcomes. Highly-expressed miR-29a-3p was an independent prognostic factor for adverse outcomes of GERD patients. Conclusion High expression of miR-29a-3p aided the diagnosis and predicted poor prognosis of GERD patients.
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