「 제민요술 」에 수록된 식품조리가공법 연구보고 (5) : 정 , 암 , 전 (煎) , 소 (消) , 저 (菹) , 록 (綠) , 적 (炙) , 신 , 오 (奧) , 조 (槽) , 포 (苞)

안명수,서혜경,이효지,윤서석,안숙자,임희수,윤숙경,조후종,윤덕인 한국조리과학회 1990 한국식품조리과학회지 Vol.6 No.4

The following, Chung, Am, Chun, Seo, Rok, Shin, Oh, Cho, Po, listed in [Che Min Yo Sul] are as follows; 1. Chung means polutry and meat like pork and beef cooked with Ja. Am is flavoring meat in a seasoned broth, which is seasoned with Yeom Shi, green onion and pepper. Chun is stir-fryed fish, beef or pork in a small amount of broth and Apchunbup, a kind of Chun, is stir-fryed with Yeom Shi Juice. 2. Cheo, Rok stands for boiled meat pickled in vinegar. 3. There are twenty kinds of Chuk, which is broiled polutry, fish, shellfish and meat like pork and beef together with vegetables and spices. 4. Shin, Oh, Po, are a type of meat preservation method by using Nurook, salt, alchol or broiling it in Bong Chuk way and then preserving it.

생활폐기물 소각장 작업복 샘플의 다이옥신 분석

박순자,신정화,신정숙,정명희,안윤경 한국의류학회 2004 한국의류학회지 Vol.28 No.2

PCDD/F(Polychlirinated dibenzo-p-dioxins and dibenzofurans) in both of treated fabric and untreated fabric for working clothes of a municipal waste incineration were determinated. The treated fabric for working clothes was developed for less exposure of PCDD/F in municipal waste incinerations. The total concentrations of PCDD/F in some parts such as surface, middle layer, inside for treated and untreated fabric were investigated. The I-TEQ value of surface was 0.23370ng ·TEQ/g for treated fabric, 0.15355ng ·TEQ/g for non-treated fabric. On the other hand, the value of middle layer was 0.00077ng ·TEQ/g, 0.00177ng ·TEQ/g, respectively. The surface of the treated fabric containing high levels PCDD/F was caused by absorption of them. Therefore, PCDD/F of the treated fabric in middle layer was less I-TEQ value than that of the untreated fabric. The treated fabric makes effect on preventing PCDD/F from permeating into human body.

카라멜화 반응 생성물의 갈색도와 항산화 효과와의 관계

신민자,윤혜현,안명수 한국조리과학회 2002 한국식품조리과학회지 Vol.18 No.6

The study was carried out to compare the relation between the color intensity and antioxidant activity of caramelization products using xylose(XY), glucose(GL), sucrose(SU), glucose+citric acid(GLCA), glucose+sodium citrate(GLSC), heated at 80, 120 and 140℃ for 24hrs, respectively. The color intensity(absorbance at 490㎚) of the browning mixtures increased as the browning temperature and time increased. But the degrees of color intensity of SU and GLCA changed very little. The hydrogen donating ability(HDA) of browning reaction products was generally enhanced as the browning temperature and time increased. When browning mixtures were heated at 80℃, the HDA of GLGC was the highest, but the HDA of GLSC was the highest when heated at 120 and 140℃. The antioxidant activities for the corn oil substrate containing the anhydrous ethanol extracts from the browning mixtures was inferior to that of SU, but was superior to that of GLCA. The relations among the color intensity, the antioxidant activity, and the hydrogen donating ability(HDA, reducing power) of the browning reaction mixtures were as follows: As the color intensity increased, the antioxidant activity decreased. The correlation coefficient of the color intensity and the antioxidant activity by regression equation was -0.73∼-0.82. As the reducing power increased, the antioxidant activity decreased. The correlation coefficient between the reducing power and the antioxidant activity by regression equation was -0.98∼-0.99. Therefore, the antioxidant activity of browning reaction mixtures seemed not correlated with the color intensity and the reducing power.

불인성 미골통에 Caudal Epidural Steroid 이용

안명자(Myung Ja Ahn),서재현(Jae Hyun Suh),김성년(S 대한통증학회 1992 The Korean Journal of Pain Vol.5 No.1

Coccygodynia is a pain syndrome resulting from trauma, fractures, infection and tumor, and is usually amenable to conservative treatment. We present one case of coccygodynia that de- veloped 2 days after percutaneous cordotomy done for pain control of cervix cancer unrespon- sive to conservative treatment which subsequently was treated with a caudal injection of lido- caine and triamcinolone. Caudal epidural steroid injection is less invasive and has less potential for complication than the neurosurgical interruption of the pain pathway.

경막외 Droperidol 투여로 발생한 Neuroleptic Malignant Syndrome - 1예 보고 -

안명자(Myung Ja Ahn),서재현(Jae Hyun Suh),김성년(S 대한통증학회 1991 The Korean Journal of Pain Vol.4 No.1

N/A The neuroleptic malignant syndrome (NMS) is an uncommon but dangerous complication of treatment with neuroleptic drugs. This syndrome is characterized by autonomic dysfunction, extrapyramidal dysfunction, and hyperthermia. NMS seems more frequent with parentral neuroleptic use. We report a patient in whom suspicious NMS was developed in the ward after epidural administration of 2. 5mg of droperidol with morphine for postoperative pain control. Extrapyramidal symptoms and autonomic dysfunction were treated with diazepam, but tem- perature was spontaneously deereased after l6 hours and 40 minute after receiving epidural droperidol.

기능성 화장품 사용에 따른 만족도와 제품에 대한 신뢰성 연구 -다기능성 화장품을 중심으로-

김영자 ( Young Ja Kim ),김명자 ( Myung Ja Kim ),유미연 ( Mi Yeon Ryu ),이성희 ( Sung Hee Lee ),이정은 ( Jung Eun Lee ),최우정 ( Woo Jung Choi ),안미자 ( Mi Ja Ahn ) 한국미용학회 2007 한국미용학회지 Vol.13 No.1

간호학 연구의 동향과 전망

김소야자(Kim, Soya-Ja),김귀분(Kim, Kwuy-Bun),이명선(Yi, Myung-Sun),이광자(Lee, Kwang-Ja),안양희(Ahn, Yang-Heui),김희순(Kim, Hee-Soon),박영주(Park, Young-Joo),고명숙(Koh, Myung-Suk),송경애(Sohng, Kyeong-Yae) 한국간호과학회 2002 Journal of Korean Academy of Nursing Vol.32 No.1

임상간호사의 업무스트레스와 소진정도에 관한 연구

안청자,이명하,김기미 中央醫學社 1989 中央醫學 Vol.54 No.7

The purpose of this study was to classify factors influencing job stress of clinical nurses, and to identify relationship between job stress and burnout and demographic characteristics for nurses. The subjects consisted of 108 staff nurses who had worked in the Chonbuk National University Hospital, this study was conducted during 3 days from May 24th to 27th, 1989. The instruments used for this study were the Job Stress Scale developed by the re-earcher and the Burnout Scale developed by Pines' and Aronson (1981). Analysis of data was done by the use of t-test, ANOVA, pearson correlation coeffecient,,factor analysis. The results were as follows; 1. In the factor analysis, job stress was classified according to 14 factors and the commulative percentage of these factors was 73.9 % the 14 factors were : 1) Night duty and unsatisfactory duty conditions, 2) Lack of professional knowledge and skill, 3) Unsatisfactory' relationship with head nurse and nursing members, 4) Inadequate reward, 5) Conflict with doctors, 6) Role conflict as a profession, 7) Conflict with patient and pt's relatives, 8) Ineffective administrative system and support, 9) Shortage of nursing personnel, 10) Poor physical environment of nursing unit, 11) Increase of workload, 12) Emotional burden due to the limitation of medicine, 13) Miscellaneous affairs, 14) Dying patients. 2. Nurses' perception for job stress and burnout 1) Mean score of job stress was 3.865 (Maximum score : 5). High degree of job stress is evident among clinical nurses. The highest rank of stress factor was dying patient, night duty and unsatisfactory duty condition, inadequate reward, conflict with doctor, shortage of nursing personnel. 2) Mean score of burnout was 2.680 (Maximum score : 5). 3.. Relationship between degree of job stress and burnout and demographic characteristics. 1) There was significant relationship between degree of job stress and burnout level (r = .2717, p < .002). 2) There was no significant relationship between_ nurses' demographic. characteristics and degree of job stress. 3) Nurses' age and working department had relation to degree of burnout significantly (age : r = .1640, P < .05, working department : r = 2.039, P < .05).

Caramel 갈색화 반응 생성물의 항산화성에 관한 연구

안명수,신민자 한국조리과학회 2000 한국식품조리과학회지 Vol.16 No.6

100℃ 이상에서 당단독, 당과 유기산 또는 유기산염의 caramel 갈색화 반응과 당과 아미노산의 Maillard갈색화 반응의 갈색화 물질의 항산화성을 측정하고자 0.1M의 xylose(XY), g1ucose(GL), sucrose(SU)를 단독으로, 0.1M glucose에 0.02M의 citric acid를 혼합한 glucosecitric acid(GLCA), 0.02M의 sodium citrate를 혼합한 glucose-sodium citrate(GLSC)와 0.1M의 glycine을 혼합한 glucose-glycine(GLGC)을 80, 120 및 140℃에서 12, 24시간 가열하여 얻은 갈색화 반응 생성물의 수소공여능(HDA)에 의한 항산화성을 측정하였으며 이들의 무수 ethanol 추출물의 옥배유 기질에 대한 항산화 효과를 측정하여 기존 항산화제(TBHQ, TOCO)와 비교, 고찰한 결과는 다음과 같았다. 1. Caramel 갈색화 반응 생성물의 수소공여능(HDA)에 의한 환원력은 갈색화 반응온도 및 시간의 경과에 따라 대체적으로 증가되었으며 갈색도가 큰 반응계일수로 환원력이 크게 나타났다. XY, GL, SU, GLCA, GLSC 및 GLGC의 갈색화 반응액의 수소공여능은 80℃에서 24시간 반응 후 각각 0.290, 0.299, 0.281, 0.301. 0.362 및 0,387로 그 크기는 GLGC>GLSC>GLCA>GL>XY>SU 순이었다. 120℃에서 24시간 반응 후의 GLCA와 GLGC에서 갈색도의 증가와는 달리 HDA는 오히려 낮아졌으며, 140℃에서는 대부분의 갈색화 반응액의 HDA는 온도가 상승함에 따라 높아졌지만 GLCA와 GLGC의 HDA는 낮아져서 각각 0.275 및 0.305로 된 반면에 GLSC의 HDA는 계속 증가하여 0.543으로 가장 높은 것으로 나타났다. 이 때의 HDA는 GLSC>SU>GL>GLGC>XY>GLCA 순이었다. 2. 갈색화 반응 생성물의 무수 ethanol 추출물을 첨가한 옥배유의 항산화 효과는 TBHQ에는 못미치나 TOCO 보다는 우수한 항산화력을 나타내는 것도 있었다. 80℃에서 24시간 진행된 갈색화 반응 생성물의 경우는 TBHQ>GLCA>GLGC>>TOCO>SU>XY>GL>GLSC>control 순으로 80℃에서는 갈색화 반응 중간생성물은 모두 항산화 효과를 나타내었으며 GLCA의 항산화 효과는 TBHQ 보다는 크게 떨어지나 GLGC, TOCO보다는 높은 항산화력을 보여주었다. 또한 120 및 140℃에서 24시간 진행된 갈색화 반응 생성물의 항산화 효과는 SU, GLCA에서만 보였으며 이들의 항산화 효과는 Maillard형 갈색화 반응액인 GLGC의 항산화 효과 보다 높았다. 그 크기는 TBHQ>SU>TOCO>GLCA>control>GLSC>GLGC>XY>GL의 순으로 80, 120및 140℃에서의 갈색화 반응 생성물의 항산화성은 80℃에서 가장 좋은 것으로 나타났다. 이상으로 볼 때 각종 갈색화 반응 생성물의 수소공여능에 의한 환원력과 항산화 효과의 관계는 환원력이 증가함에 따라 항산화 효과는 중가하지 않고 감소하여 갈색화 반응물의 항산화 효과와 환원력 사이에는 뚜렷한 상관관계가 없는 것 같았다. The study was carried out to compare the antioxidant activities of products from caramel-type-browning reaction of xylose(XY), glucose(GL), sucrose(SU), glucose + citric acid (GLCA), glucose + sodium citrate(GLSC), glucose + glycine(GLGC) heated at 80, 120 or 140℃ for 24 hr. 1. The hydrogen donating ability (HDA) of browning reaction products was generally enhanced as the browning temperature and time increased. The HDAs of the browning reaction products heated at 80℃ for 24 hr were in the order of GLSC (0.387)>GLSC (0.362)>GLCA (0.301)>GL(0.299)>XY(0.290)>SU(0.281). But they were in the order of GLSC (0.543)>SU(0.328)>GL(0.309) >GLGC(0.325)>XY(0.298)>GLCA(0.275) under the condition of heating at 140℃ for 24 hr. 2. The antioxidant activities of the anhydrous ethanol extracts of the browning mixtures were inferior to that ofTBHQ as measured in corn oil, but SU was superior to tocopherol in its antioxidant activity. All the browning mixtures showed antioxidant activities when heated at 80℃; however, only SU and GLCA showed the activities at 120 or 140℃. And the antioxidant activity of the SU extract was higher than that of TOCO. The antioxidant activities of the ethanol extracts were in the order of TBHQ>GLCA>GLGC>TOCO>SU>XY>GL>GLSC>control at 80℃, TBHQ>SU>TOCO>GLCA>control>GLSC>XY>GL>GLGC at 120℃, and TBHQ>SU>TOCO>GLCA>control >GLSC>GLGC>XY>GL at 140℃

A Case of Immunoablative High-dose Cyclophosphamide Therapy without Stem Cell Rescue in the Treatment of Refractory Rheumatoid Arthritis Patient

Ahn, Myung-Ju,Lee, In-Hong,Jung, Ja-Hun,Choi, Jung-Hye,Cho, Kyung-Ran,Kim, Seong-Yoon 대한조혈모세포이식학회 2000 대한조혈모세포이식학회지 Vol.5 No.1

류마치스 관절염은 만성염증질환으로 경미한 증상으로부터 생명을 위협할 만한 중증의 경우까지 임상적으로 매우 다양하다. 이러한 기존의 치료에 불응하거나 재발이 반복되는 환자들에게 고용량항암제 및 자가조혈모세포이식이 시행되고 있으며, 최근에는 자가조혈모세포이식없이 고용량의 cyclophosphamide만으로 치료했을 때에도 임상적 관해가 유도됨이 보고되고 있다. 저자 등은 34세 여자 환자로 기존의 약제에 불응하고 반복 재발된 류마치스 관절염 환자에서 조혈모세포의 주입없이 고용량 cyclophosphamide를 투여하여 성공적으로 생착된 1예를 경험하였기에 보고하는 바이다. 환자는 200 mg/kg cyclophosphamide를 4일간에 걸쳐 정맥주사하였고 치료 6일째부터 5 ug/kg의 G-CSF 를 피하주사하였다. 호산구가 500/mm³이상으로 회복되는 기간은 14일이었고 혈소판 감소증은 관찰되지 않았다. 독성으로는 WHO 1도의 오심과 2도의 구내염이 있었다. 치료 후 환자는 rheumatoid factor가 음성으로 전환되었고 관절증세가 호전되어 외래 추적 중이다. 결론적으로 조혈모세포주입없이 고용량 cyclophophamide 치료는 독성이 적고 안전한 시술로 생각되며 향후 더 많은 수의 환자와 장기간의 추적을 통해 이 시술의 임상적 의의를 구명해야 할 것으로 사료된다. Rheumatoid arthritis (RA) is a chronic inflammatory disease and shows heterogeneous disease process from mild articular symptoms to severe, life- threatening disease. Recently, the use of high-dose immunosuppressive therapy followed by autologous stem cell transplantation has been proposed as another treatment modality for severe, refractory rheumatoid arthritis. Moreover, it has been reported that high-dose cyclophosphamide therapy without stem cell rescue can induce complete remission in patients with refractory, severe autoimmune disease. We describe here a case of successful immunoablative high-dose cyclophosphamide therapy without stem cell rescue in the treatment of a 34-year-old refractory rheumatoid arthritis patient. The patient received 200 mg/kg of cyclophosphamide without stem cell rescue and G-CSF (5 ug/kg) was administered after 6 days of chemotherapy. The time to ANC >1,000/mm3 was 14 days and there was no episode of thrombocytopenia. There were only WHO grade I nausea and grade II stomatitis. On two months follow-up, the patient is doing well without joint pain and has improvement of laboratory findings (ESR 8 mm/hr, Ritchie index O, CRP 0.42 mg/dL). And also rheumatoid factor was <20 IU/ml indicating seronegative conveision. These results indicate that high-dose cyclophosphamide without stem cell rescue could be safe and tolerable. To evaluate the clinical efficacy, further long-term follow-up will be needed.