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( Ja Ryong Jeon ),( Joon Seong Ahn ),( Hong Seok Yoo ),( Taek Kyu Park ),( Dong Mo Je ),( Hye Min Jeong ),( Kwang Hyuck Lee ) 대한내과학회 2014 The Korean Journal of Internal Medicine Vol.29 No.1
A 71-year-old male patient was readmitted to our hospital 1 month after discharge because of relapse of abdominal pain. He had been diagnosed with hepatocellular carcinoma (HCC) 1 year prior and had undergone repeated transcatheter arterial chemoembolization and radiotherapy. During the last hospitalization, he was diagnosed with a liver abscess complicated by previous treatments for HCC and was treated with intravenous antibiotics and abscess aspiration. Follow-up abdominal computed tomography revealed a liver abscess with a duodenal fistula, which was successfully treated with endoscopic Histoacryl injection into the fistula. Liver abscesses with duodenal fistulas rarely occur, but they are intractable and possibly fatal in patients with HCC. In the literature, they have frequently been managed only with abscess treatment without fistula management. We herein report the first case of a patient with a liver abscess complicated by a fistula between the duodenum and the abscess, which was treated with endoscopic Histoacryl injection.
자동차용 고장력강 DP590의 인장 및 저되풀이수 피로물성 평가
구자석(Ja-Suk Koo),최재석(Jae-Seock Choi),전태룡(Tae-Ryong Jeon),허용학(Yong-Hak Huh),이해무(Hae-Moo Lee) 한국자동차공학회 2005 한국자동차공학회 춘 추계 학술대회 논문집 Vol.2005 No.5_2
Tensile and low cycle fatigue properties of high strength steel DP590 used for automotive chassis parts are evaluated. Test specimens are made of DP590 plate after painting and baking process. Load cell calibration, extensometer calibration and specimen alignment are performed to enhance the accuracy and precision. In addition, the guiding apparatus is made in order to prevent buckling when compression loading is present. When DP590 replaces SAPH370, the fatigue life of the lower control arm increases by 2 or 3 times.
( Joon Seong Ahn ),( Ja Ryong Jeon ),( Hong Seok Yoo ),( Taek Kyu Park ),( Cheol Keun Park ),( Dong Hyun Sinn ),( Seung Woon Park ) 대한간학회 2013 Clinical and Molecular Hepatology(대한간학회지) Vol.19 No.2
Hepatoid adenocarcinoma (HAC) is a rare type of extrahepatic carcinoma whose morphology is similar to that of hepatocellular carcinoma (Hcc).Metachronous HCC and HAC in the Same patient is extremely rare. The case of a 68-yearold man with chronic hepatitis B infection who had both Hcc and HAC of the stomach is reported herein. Nine years previously this patient had been diagnosed with HCC received a right lobectomy. HCC that recurred at the caudate lobe at 6 months after the operation was successfully treated with transarterial chemoembolization. The patient was followed up regularly thereafter without evidence of tumor recurrence for 9 years. In July 2010 his serum alpha-fetoprotein (AFP) level elevated from 6.5 ng/mL, and he developed a probable single metastatic Iymph node around the hepatic artery without intrahepatic lisions. Subsequent evaluation with upper endoscopy revealed a 4-cm ulcerative lesion on the antrum of the stomach. Subtotal gastrectomy was performed with Iymph-node dissection. Histologic examination revealed a special type of extrahepatic AFP-producing adenocarcinoma-HAC with Iymph-node metastasis-which indicates that HAC can be a cause of elevated AFP even in patients with HCC. HAC should be considered if a patient with stable HCC exhibits unusual elevation of AFP.
Paraquat 중독 환자에 대한 hemoperfusion 과 continuous veno-venous hemofiltration 의 치료 효과
노희종(Hee Jong Noh),구자룡(Ja Ryong Koo),이정열(Jeong Yeol Lee),주민하(Min Ha Joo),전만조(Man Jo Jeon),김진철(Jin Cheol Kim),김근호(Gheun Ho Kim),전노원(Rho Won Chun),김형직(Hyung Jik Kim),채동완(Dong Wan Chae),노정우(Jung Woo Noh) 대한내과학회 2000 대한내과학회지 Vol.59 No.6
N/A Background : In Korea, paraquat accounts for most of fatal poisoning with 500 or more deaths per year. It has been known that patients who ingested more than 1/2 mouthful of 20% concentrate paraquat usually die of multiorgan failure and pulmonary fibrosis. But the effect of charcoal hemoperfusion which can enhance elimination of paraquat remains controversial. Because acute paraquat poisoning is also characterized by multiorgan failure including kidney and marked rebound in plasma paraquat level after hemoperfusion, Continuous veon-venous hemofiltration(CVVH) may have theoretical benefits in the treatment of paraquat poisoning. So we evaluated the effect of early charcoal hemoperfusion and prophylactic CVVH after hemoperfusion in patients with paraquat poisoning. Methods : There were 80 patients with paraquat poisoning admitted within 24 hours after ingestion (August 1996 - March 1998). All of them were treated with hemoperfusion (duration of hemoperfusion, 6.4±3.0 hours) within 24 hours of ingestion. The amount of ingestion was 2.1±1.0 mouthful (as 20% concentrate) and 78 (98%) were urine sodium dithionite test positive which is a poor prognosis factor. Forty-four patients received hemoperfusion only and 36 were followed by CVVH (duration, 50.4±20.9 hours; ultrafiltration volume, 33.8±3.9 L/day) after hemoperfusion. Results : There was no difference between the hemoperfusion group and hemoperfusion+CVVH group in age, sex, initial serum creatinine, arterial oxygen saturation, severity of poisoning (as assessed by serum paraquat level determined by HPLC and amount of ingestion), or in the time elapsed from ingestion to the beginning of hemoperfusion. The total mortality was 65% (52/80) with no difference between the hemoperfusion group (64%, 28/44) and hemoperfusion+CVVH group (67%, 24/36). The mortality according to amount of ingestion was as follows: 〈 1 mouthful, 0% (0/5); 1 mouthful, 53% (8/15); 2 mouthful, 65% (11/17); ≥ 3 mouthful, 82% (27/33); unknown, 60% (6/10). Conclusion : Early hemoperfusion can be effective in reducing mortality in patients who ingest less than 2 mouthful. Even though prophylactic CVVH after hemoperfusion has no additional benefit in reducing mortality in paraquat poisoning, it prolonged the time to death after ingestion.(Korean J Med 59:651-656, 2000)
김진철,이정열,구자룡,윤종우,채동완,김근호,전노원,노정우,김형직,노희종,주민하,전만조 대한내과학회 2001 대한내과학회지 Vol.60 No.5
Paraquat, a very potent herbicide, has produced many fatalities through indiscriminate usage and suicides. It is known that with ingestion of more than one mouthful of 20% paraquat, death usually occurs by pulmonary fibrosis. We experienced two cases of successful outcome in patients with paraquat poisoning complicated with pulmonary fibrosis through active, intensive treatment from the early phase after ingestion. They swallowed one to two mouthfuls of the 20% commercial paraquat, and received hemoperfusion within 2-3 hours after ingestion. Then, combination therapy with steroid, vitamin C, D-penicillamine, allopurinol, colchicine was administered from the early phase. They showed moderate to severe hypoxemia and pulmonary fibrosis on chest HRCT during hospital course, but recovered from hypoxemia and remained very well on follow up over 3 months and 12 months after ingestion, respectively. We report these cases with literature review on treatment and prognosis of paraquat poisoning. (Korean J Med 60:490-495, 2001)
강창호(Chang-Ho Kang),정호건(Ho Geon Jeong),구자륭(Ja-Ryong Koo),전은진(Eun Jin Jeon),곽대영(Dae Yung Kwak),홍채환(Chae Hwan Hong),김시환(Si Hwan Kim),서지연(Ji Yeon Seo),한도석(Do Suck Han),소재성(Jae-Seong So) 한국생물공학회 2012 KSBB Journal Vol.27 No.3
Lactic acid is an important product arising from the anaerobic fermentation by lactic acid bacteria (LAB). It is used in the pharmaceutical, cosmetic, chemical, and food industries as well as for biodegradable polymer and green solvent production. The poly lactic acid (PLA) is an important material for bio-plastic manufacturing process. For PLA production by new LAB, we screened LAB isolates from shellfish. A total of 28 LAB were isolated from various shellfishes. They were all Gram positive, oxidase and catalase negative. Based on API 50CHL kit, 7 strains among the 28 isolates were identified as Lactobacillus plantarum, 6 strains as Lactobacillus delbrueckii, 5 strains as Leuconostoc mesenteroides, 3 strains as Lactobacillus brevis, 2 strains as Lactococcus lactis, 1 strain as Lactobacillus salivarius, 1 strain as Lactobacillus paracasei, 1 strain as Lactobacillus pentosus, 1 strain as Lactobacillus fermentum and 1 strain as Pediococcus pentosaceu. Also, we examined the amount of total lactic acid produced by these new strains by HPLC analysis with Chiralpak MA column. One strain E-3 from Mytilus edulis was indentified as Lactobacillus plantarum and found to produce 20.0 g/L of D-form lactic acid from 20 g/L of dextrose. Further studies are underway to increase the D-lactic acid production by E-3.
( Mi Hyeon Lee ),( Joo Hyun Jun ),( Eun Mi Choi ),( Eun Mi Kim ),( Young Ryong Choi ),( Pil Hyun Jeon ),( Seung Hwa Baek ),( Mi Hwa Chung ),( Wha Ja Kang ) 경희대학교 경희의료원 2016 慶熙醫學 Vol.31 No.1
Paragangliomas are rare tumors that arise from extra-adrenal chromaffine tissues and that secrete catecholamine. The abnormal secretion of catecholamine can cause cardiovascular complications such as severe hypertension, cardiomyopathy, cardiac arrhythmia, and aortic aneurysm rupture. In particular, the risk of mortality and morbidity increases if the patient has not been diagnosed or if the preparation for a possible hypertensive crisis has been insufficient. Moreover, it can lead to high risks of cardiovascular complications if the patient has a concomitant disorder such as aortic aneurysm. We report a case of preoperatively undiagnosed paraganglioma that caused a hypertensive crisis during the surgical removal of a retroperitoneal mass and the repair of an infra-renal abdominal aortic aneurysm (AAA) and left common iliac artery aneurysm.
이준희 ( Jun Hee Lee ),박혜연 ( Hye Yon Park ),이민지 ( Min Ji Lee ),이윤정 ( Yoon Jung Lee ),안준성 ( Joon Seong Ahn ),전자룡 ( Ja Ryong Jeon ),김호중 ( Ho Joong Kim ) 대한내과학회 2012 대한내과학회지 Vol.83 No.3
저자들은 만성 기침과 객담, 호흡곤란을 호소하는 환자에서 기관지연화증을 동반한 기관기관지거대증을 진단하였기에 그 사례를 문헌고찰과 함께 보고하는 바이다. Tracheobronchomegaly, or Mounier-Kuhn syndrome, is a rare clinical and radiologic condition characterized by marked tracheobronchial dilatation and recurrent lower respiratory tract infections. It is thought to be due to a congenital anomaly. A diagnosis is typically made using computed tomography (CT) and bronchoscopy. Symptoms can range from minimal with preserved lung function to severe respiratory failure. Here, we present the case of a 50-year-old male who was referred to our hospital for chronic cough, sputum, and dyspnea. In addition, the patient showed tracheobronchomegaly with bronchomalacia on CT and bronchoscopy. This report describes a rare case of Mounier-Kuhn syndrome with a literature review.