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가축과 실험동물의 생리자료 (5)-2 : 제5장 양-2(완)
권해병,정순동,양일석 진주농과대학 1970 진주농과대학 연구논문집 Vol.- No.9
Harvey(153)에 의하면 불소 함유량은 2.0ppm(2마리, 건조한 조직, Gastrocnemius)이다. Clarke et al.(149)에 의하면 신선한 근육일 경우 Calcium 10~20mg/100g,염소 70mg/100g, Magnesium 33mg/100g,인 185~210mg/100g, Potassium 205~295mg/100g, Sodium 80~110mg/100g,단백질 17.1%, 지질(총량) 17.~32%,인지질 4.7%이고 Cholesterol은 건조한 조직의 0.26%이다.
만성 B형 간염환자에서 인터페론 치료 후 간 조직검사 소견의 변화와 Tumor Necrosis Factor의 임상적 의의
김홍수,윤동진,김은주,정일권,박상흠,이문호,김선주 순천향의학연구소 2000 Journal of Soonchunhyang Medical Science Vol.6 No.2
Background: Interferon has been widely used in the treatment of chronic hepatitis B, but its effectiveness is debatable. The clinical indices as the loss of HBeAg, HBV DNA, and improvement of liver function are applicated to identify the effectiveness of interferon therapy, but the mechanism of hepatohistological change is not well known. We investigated the changes of histologic finding and plasma tumor necrosis factor(TNF) in the patients with chronic hepatitis B after treatment with interferon-alpha. Methods: 11 patients with chronic hepatitis B who had treated by interferon-alpha were enrolled for this study. Liver biopsy was done before and after treatment of interferon and plasma TNF was evaluated at the same time. A semiquantitative study using a histologic scoring system was applied on pre and post liver biopsy specimens and the changes of HBeAg and HBV DNA were also evaluated. Results: Among subjects, the response group, recurrence group, and non-response group based on serologic response with clearance of HbeAg were6, 3, and 2 patients, respectively. The changes of serum ALT level and HBV DNA titer on pre and post therapy decreased significantly in the response group. The change of mean plasma TNF level in the response group decreased insignificantly to 19.4 from 19.9. The histological improvements of grading and staging were shown 4 patients in the response group. Conclusions: Serologic response with clearance of HBeAg was associated with histolofical improvement. The loss of HBsAg in the serum was significant indicator of reduction in the amount of HBV core antigen and HBV surface antigen in the hepatocytes. Plasma TNF level was not associated with response of interferon-alpha therapy and histologic activity.
Helicobacter pylori and Telomerase Activity in Intestinal Metaplasia of the Stomach
( Il Kwun Chung ),( Kyu Yoon Hwang ),( In Ho Kim ),( Hong Soo Kim ),( Sang Heum Park ),( Moon Ho Lee ),( Chang Jin Kim ),( Sun Joo Kim ) 대한내과학회 2002 The Korean Journal of Internal Medicine Vol.17 No.4
Background: Helicobacter pylori (H. pylori) has been considered a definitive carcinogen in gastric cancer. Telomerase is activated in gastric cancer and some premalignant gastric lesions, including intestinal metaplasia (IM). In this study, we evaluated t
(Il Kwun Chung),(Soo Jin Hong),(Eun Joo Kim),(Joo Young Cho),(Hong Soo Kim),(Sang Heum Park),(Moon Ho Lee),(Sun Joo Kim),(Chan Sup Shim) 대한내과학회 2001 The Korean Journal of Internal Medicine Vol.16 No.3
N/A Background: It has been debated which diagnostic test should be preferred for the diagnosis of Helicobacter pylori (HP) in patients with peptic ulcer diseases. Several limitations are reported in bleeding peptic ulcers be cause of intragastric blood and possibility of changed numbers of organisms by medication. This study was designed to find out the best method for diagnosis of HP infection, in aspect of deciding the times of detection and the specific tests in bleeding peptic ulcers. Methods: We prospectively examined histology, rapid urease test (CLO test), urea breath test (13C-UBT) and serology in HP diagnostics in 32 patients with bleeding peptic ulcers to detect HP infection. Each test was performed two times (four methods at first 24 hours and former three methods at 7th day after initial therapeutic endoscopy). We evaluated the sensitivity of each test, compared the two-times results and evaluated the effect of these tests to an outcome of endoscopic hemostasis. Results: Diagnostic sensitivities of histology, CLO test, 13C-UBT and serology are 75 %, 67.8 %, 100 % and 100 % at first endoscopy, and 71.4 %, 78.5 %, 89.3 % at 7th day endoscopy, respectively. Histologic study and CLO test had diagnostic limitation at emergent first endoscopy contrary to UBT (p <0.01). Histologic study, CLO test and UBT have limitations at 7th day endoscopy. Only 3 patients (9.4 %) rebled with subsequent complete endoscopic hemostasis and all diagnostic tests at initial endoscopy did not influence the outcome of hemostasis. Conclusion: First day histologic and CLO tests are inadequate methods in detecting HP infection in patients with bleeding peptic ulcers. 7- day histologic, CLO test and UBT have a low sensitivity. First-day UBT can be a standard test to diagnose HP infection in patients with bleeding peptic ulcers.
Il-Kwun Chung 대한소화기내시경학회 2012 Clinical Endoscopy Vol.45 No.3
Endoscopy has its role in the primary diagnosis and management of acute non-variceal upper gastrointestinal bleeding. Main roles of endoscopy are identifying high risk stigmata lesion, and performing endoscopic hemostasis to lower the rebleeding and mortality risks. Early endoscopy within the first 24 hours enables risk classification according to clinical and endoscopic criteria, which guide safe and prompt discharge of low risk patients, and improve outcomes of high risk patients. Techniques including injection therapy, ablative therapy and mechanical therapy have been studied over the recent decades. Combined treatment is more effective than injection treatment, and single treatment with mechanical or thermal method is safe and effective in peptic ulcer bleeding. Specific treatment and correct decisions are needed in various situations depending on the site, location, specific characteristics of lesion and patient’s clinical conditions.
Chung, Il Jun,Kim, Wook,Jang, Wonjun,Park, Hyun-Woo,Sohn, Ahrum,Chung, Kwun-Bum,Kim, Dong-Wook,Choi, Dukhyun,Park, Yong Tae The Royal Society of Chemistry 2018 Journal of materials chemistry. A, Materials for e Vol.6 No.7
<P>Triboelectric nanogenerators (TENGs) are considered promising next-generation mechanical energy harvesters owing to their desirable attributes such as light weight, portability, eco-friendliness, and low cost. However, cost-effective, scalable, and facile manufacturing methods are still required for the commercialization of TENGs, especially for textile-type TENGs compatible with a variety of textile products. In this work, we report for the first time the layer-by-layer (LbL) assembly of graphene multilayers for low-cost, durable, scalable, and wearable TENGs. The LbL-based graphene multilayers are fabricated on polymer substrates with flat, undulated, and textile surfaces, where graphene multilayers play dual roles as a positive tribo-material and as an electrode. The polymer substrate here is utilized as a negative tribo-material. We identify the optimal number of layers for graphene composites and analyze this outcome using their morphological and electrical properties. Due to the hydrogen bonding-based LbL wet processes, graphene composite multilayers could be well deposited on undulated surfaces as well as on large-scale fabric textiles. These LbL-deposited graphene multilayers yield graphene based-TENGs (G-TENGs) with high durability and high performance. Finally, a graphene multilayer on a textile sample is demonstrated as a scalable and wearable textile-based G-TENG (TG-TENG) operated in a single electrode mode, thereby enabling low-cost manufacturing and high compatibility with textile products such as cloths, curtains, bags and so on. The simple, cost-effective, scalable, and versatile LbL assembly can therefore enable the fabrication of wearable energy harvesting sources for many portable personal microelectronic devices (<I>e.g.</I>, self-powered wireless sensors).</P>
An analysis of Different Methods to Diagnose Helicobacter Infection in Bleeding Peptic Ulcers
정일권 ( Il Kwun Chung ),홍수진 ( Soo Jin Hong ),김은주 ( Eun Joo Kim ),조주영 ( Joo Young Cho ),김홍수 ( Hong Soo Kim ),박상흠 ( Sang Heum Park ),이문호 ( Moon Ho Lee ),김선주 ( Sun Joo Kim ),심찬섭 ( Chan Sup Shim ) 대한내과학회 1999 대한내과학회 추계학술대회 Vol.57 No.-
소화성궤양 가이드라인 출혈 소화성궤양 치료의 가이드라인
정일권 ( Il Kwun Chung ),이동호 ( Dong Ho Lee ),김흥업 ( Heung Up Kim ),성인경 ( In Kyung Sung ),김진호 ( Jin Ho Kim ) 대한소화기학회 2009 대한소화기학회지 Vol.54 No.5
Peptic ulcer (PU) bleeding is the main cause of non-variceal gastrointestinal bleeding. Negative outcomes include re-bleeding and death, and many of the deaths are associated with decompensation of coexisting medical conditions precipitated by acute bleeding event. Accurate analysis of risk for clinical features can help physician to decide treatment modality. Endoscopy can detect bleeding stigmata and perform therapeutic hemostasis. Proton pump inhibitor (PPI) compared with placebo or H2RA reduces mortality following PU bleeding among patients with high-risk endoscopic findings, and reduces re-bleeding rates and surgical intervention. PPI treatment initiated prior to endoscopy in upper gastrointestinal (UGI) bleeding significantly reduces the proportion of patients with stigmata of recent hemorrhage (SRH) at index endoscopy but does not reduce mortality, re-bleeding or the need for surgery. The strategy of giving oral PPI before and after endoscopy, with endoscopic hemostasis for those with major SRH, is likely to be the most cost-effective. The treatment of H. pylori infection was found to be more effective than anti-secretory therapy in preventing recurrent bleeding from PU. H. pylori eradication alone and eradication followed by misoprostol (with switch to PPI, if misoprostol is not tolerated) are the two most cost-effective strategies to prevent ulcer bleeding among H. pylori-infected NSAID users, although the data cannot exclude PPIs also being cost-effective treatment. This review focuses specifically on the current treatment of patients with acute bleeding from a peptic ulcer. (Korean J Gastroenterol 2009;54:298-308)