림프종 환자에서의 갈륨, TI-201 그리고 Tc-99m MIBI 섭취의 비교

천경아,조인호,원규장,이경희,이형우,현명수,이재태,이규보 영남대학교 의과대학 2002 Yeungnam University Journal of Medicine Vol.19 No.2

Purpose; Ga-67 scintigraphy has been used for the evaluation of tumors, especially lymphoma. Recently, Tl-201 and Tc-99m MIBI were also used to tumor imaging. Tl-201 and Tc-99m MIBI had better physiologic characteristics than Ga-67, so we studied 32 biopsy proven lymphoma patients (male 24, female 8, mean age 46 years) with Ga-67, Tl-201 or Tc-99m MIBI and compared the scan findings. Materials and Methods: Twenty-three of 32 patients were injected 74-111 MBq (2-3 mCi) of Tl-201, before chemotherapy and imaged with dual-headed SPECT (Prism 2000, Picker, USA) at 30 minutes after injection. Delayed images were obtained after 3 hr in 8 patients. Twenty seven of 32 patients were injected 740 MBq (20 mCi) of Tc-99m MIBI and imaged at 30 minutes after injection. 111-185 MBq (3-5 mCi) of Ga-67 was injected in 12 patients and imaged at 48 and 72 hours after injection. Twenty eight patients were diagnosed as non-Hodgkin's lymphoma and others were Hodgkin's lymphoma. Results: Twenty patients were positive on Tl-201 scan and 3 patients showed negative findings. One of these 3 patients, Tc-99m MIBI and Ga-67 scan were positive. Twenty two patients were positive on Tc-99m MIBI scan and 5 patients showed negative findings. One of these 5 patients, Tl-201 was positive and 2 were positive on Ga-67 scan. Ten of 12 patients showed positive findings on Ga-67 scan. The sensitivity of these agents were 83.3%, 87.0% and 81.5% for Ga-67, Tl-201 and Tc-99m MIBI, respectively. The sensitivity was highest in Tl-201 scan, but there were no significant differences among three tests. In this study, there was no significant difference of uptake ratios between early and delayed images of Tl-201. Conclusion: Scintigraphy with Tl-201 and Tc-99m MIBI in lymphoma patients have similar sensitivity with Ga-67.

Gene pyramiding effect of two major bakanae disease resistance gene using qBK1 and qBKWD

Sais-Beul Lee,Tae-Heon Kim,Su-Min Jo,Jun-Hyun Cho,Ji-Yoon Lee,Jong-Hee Lee2,Dongjin Shin,You-Chun Song,Myung-Kyu Oh,Dong-Soo Park 한국작물학회 2017 한국작물학회 학술발표대회 논문집 Vol.2017 No.-

도시하천의 환경 친화적 개선방안에 관한 조사연구

이길영,권득용,김영안,한천규 대전대학교 산업기술연구소 1999 산업기술연구소 論文集 Vol.10 No.1

The three main steams flowing through Taejon have some serious problems to be solved or improved. They are : First, the uniform cross section of the rivers should be changed. Second, the extension of the riverside road should be reconsidered. Third. the neighborhood parks on the flood plain should be modified. Fourth, the flood plain parking place must not be constructed. Fifth, the ecosystem will be destroyed by the structure constructed along the rivers. In this study, we suggest that the investment and research on the development of the new technology for the setting the rivers in natural condition should be needed now and the continuous investigation and long-term plan to preserve the ecosystem of the rivers should be required. The environmental conditions of Taejon-stream, Yudung-stream and Kap-stream are indicators of the standard of living of the citizens in Taejon. Now is the time to reconsider the careless construction around the rivers and to prepare the long-term plan for the protection of the ecosystem and natural environment.

Pectolytic Enzyme에 關한 硏究 (第一報) : 分離細菌 ??가 生産하는 Macerating Enzyme와 Pectolytic Enzymes에 關하여 Ⅰ. Macerating Enzyme and Pectolytic Enzymes Produced by Isolated Bacteria (??)

李千洙,金鍾奎,奇宇京,成洛癸 慶尙大學校 1972 論文集 Vol.11 No.-

고구마 軟腐病所에서 分離한 細菌 ??가 生産하는 酵素中에서 macerating acton을 하는 酵素를 究明하기 위한 資料로 쓰기 위해 macerating enzyme의 生成에 미치는 pectin의 影響과 生成한 macerating enzyme와 pectolytic enzymes의 一般전 性質을 조사한 결과는 다음과 같다. 1. 細菌 ??는 酵素生成培地(wheat bran media)에 pectin을 加하므로써 macerating enzyme을 效果的으로 生産했다. 2. pectic acid liquefying activity, pectin liquefying activity, pectin esterase,와 macerating enzyme은 各各 1) 最適作用 pH가 7.2∼7.8, 7.2, 6.0, 6.5∼7.5 2) 最適作用溫度는 50℃, 50℃, 60℃, 50℃ 3) pH 安定性은 3.0∼8.0, 5.0∼8.0, 3.0∼8.0, 및 3.0∼8.0이었다. The influence of pectin on production of macerating enzyme by isolated bacterial ?? and the enzymological properties of its macerating enzyme produced and pectolytic enzymes were studed. The results obtained were summarized as follows: 1. Macerating enzyme was effectively produced in the media adding pectin. 2. The optimum pH of pectic acid liquefying activity, pectin liquefying activity, pectin esterase and macerating enzyme were 7.2∼7.8, 7.2, 6.0 and 6.5∼7.5 respectively. 3. The optimum temperature of pectic acid liquefying activity, pectin liquefying activity and macerating enzyme were 50℃., and that of pectin esterase was 60℃. 4. The pH stability of pectic acid liquefying activity, pectin esterase and macerating enzyme were 3.0∼8.0, and that of pectin liquefying activity was 5.0∼8.0.

키토산 미소구체가 약물방출에 미치는 영향

전윤,차월석,권규혁,이동병 조선대학교 생산기술연구소 2000 生産技術硏究 Vol.22 No.1

In this study, we examined about effectives of the drug release by used glutaraldehyde amount and molecular weight varieties of chitosan in DDS. The release experiments of chitosan microspheres containing norfloxacin were operated in the phosphate buffer solutions of pH 7.4 and 37℃, and its results were as follows. In the linearly release time of drug, chitosan microspheres (Mw 190,000) of used glutaraldehyde 1 mL and 2 mL were 45 and 64 days, and chitosan microspheres (Mw 350,000) of used glutaralhyde 1 mL and 2 mL were 60 and 80 days relatively. These results showed more effective drug releases in the increments of molecular weight and glutaraldehyde In short, the formulation allows chitosan microspheres to suppress the burst effect of the drug release mechanism, which led to the controlled release pattern and microspheres

코크스 제조 및 사용 공정에서의 코크스오븐 배출물질 연구

이종천,안규동,조광성,이병국 한국산업위생학회 2001 한국산업보건학회지 Vol.11 No.2

This study was performed to evaluate the coke oven emissions (COE) and polynuclear aromatic hydrocarbon levels in coke manu- facturing industry, secondary lead smelting industry and glass bottle manufacturing industry. 1. There were no significant difference between the means of personal samples and area samples by the types of industry(p>0.05). The levels of airborne total particulates of the secondary lead smelting industry was the highest(2.30㎎/㎥), and those of the coke manu- facturing industry and glass bottle manufacturing industry were 1.95 ㎎/㎥ and 1.37 ㎎/㎥. The concentration of COE was the highest in the glass bottle manufacturing industry(0.79 ㎎/㎥), and in order of 0.19㎎/㎥ in the coke manufacturing industry and 0.05 ㎎/㎥ in the secondary lead smelting industry. COE/total particulates(%) was highest in the glass bottle manufacturing industry(58.1%) and in order of 10.3% in the coke manufacturing industry and 3.1% in secondary lead smelting industry. There were significant differences in the total particle concentration and Coe by the types of industry(p<0.05) 2. The levels of airborne total particulates was the highest at the smelting process of secondary lead smelting industry(2.30±0.72 ㎎/㎥), and the lowest at the smelting process of glass bottle manufacturing industry (0.99±1.22㎎/㎥) Concentration of COE was the highest at the casting process of glass bottle manufacturing industry (1.09±1.15㎎/㎥), the lowest at the smelting process of secondary lead smelting industry(0.06±0,03 ㎎/㎥). The COE/total particulates(%) was the highest at the casting process of glass bottle manufacturing industry(65.9±20.5%), and the lowest at the smelting process of secondary lead smelting industry(3.1±2.7%). 3. There were positive correlations between level of The airborne total particulates and concentration of COE in COKE manufacturing industry and glass bottle manufacturing industry(p<0.05), but negative correlation in secondary lead smelting industry. 4. The numbers of case and rates that over the Threshold Limit Values(TLVs) were 24 (77.4%)cases in glass bottle manufacture, 14(23.7%) cases in the coke manufacturing industry and no one case in secondary lead smelting industry. Total numbers of case and rates that over TLVs were 38(35.5%) cases. 5. The limit of detection(LOD) for PAH was 10 ㎍/㎖) in standard sample. All PAH levels of the cokes manufacturing industry and the secondary lead smelting industry and the glass bottle manufacturing industry were trace or not to detect.

폴리머 시멘트 콘크리트의 동결융해 저항 특성 연구

이필호,이구연,전철수,연규석 강원대학교 부설 석재복합신소재 제품연구센터 2000 석재연 논문집 Vol.5 No.-

본 연구에서는 폐재자원인 광미를 잔골재의 일부로 사용하여 폴리머 시멘트 콘크리트를 제작하고 강도 특성 및 동결융해저항 특성을 실험적으로 구명하였다. 압축강도는 광미 혼입유물에 따라 262.5kg/㎠에서 422.9kg/㎠, 250kg/㎠에서 386.4kg/㎠로 증가하였으며, 휨강도는 44kg/㎠에서 107kg/㎠, 41kg/㎠에서 104kg/㎠로 증가하는 경향을 보였다. 이 결과 폴리머-시멘트비가 증가할수록 항도가 증대됨을 알 수 있으며, 광미를 사용할 경우 광미의 첨가로 내부 공극의 감소됨으로써 약간 증가된 것으로 판단된다. 폴리머 시멘트비가 0%일 경우 흡수율은 광미 무혼입의 경우 6.1%보다 광미 혼입의 경우 5.61%로 다소 낮은 값을 얻었으며, 폴리머 시멘트비가 20%일 경우에도 광미 무혼입의 경우 0.82%보다 광미 혼입의 경우 0.58%로 낮은 값을 얻을 수 있었다. 이 결과 폴리머 시멘트비가 증가할수록 흡수율이 작아졌으며, 폴리머를 혼입한 경우 흡수율이 48시간 동안 지속으로 증가함을 알 수 있었다. 폴리머 시멘트비가 5%에서 광미 무혼입의 경우 100.8%, 광미 혼입의 경우 106.6%로 가장 높은 상대 동탄성 계수를 얻어 폴리머의 혼입으로 인해 내구성이 향상되었음을 알 수 있었으며, 광미를 혼입함으로써 높은 상대 동탄성 계수를 얻을 수 있음을 알 수 있다. 폴리머 시멘트비가 5%에서 내구성 지수가 광미 무혼입의 경우 100.8%, 광미 혼입의 경우 106.6%로 크게 증가하였음을 알 수 있었고, 폴리머를 첨가한 경우에 있어서 내구성 지수가 상당히 높은 값을 나타냄을 알 수 있었다. Metal-mine tailing was added as a source of fine aggregate for polymer cement concrete(MTPCC) which was investigated with respect to the properties of strength and the resistance of freezing and thawing. Strength of MTPCC was improved over olymer cement concrete(PCC). It was believed that the addition of metal-mine tailing decreased the porosity of the fine aggregates to improve strength of the polymer cement concrete. It was found that the resistance to freezing and thawing of MTPCC was improved over PCC.

암석 슬러지를 이용한 건자재 개발

이필호,이구연,전철수,연규석,이윤수,인교진 강원대학교 부설 석재복합신소재 제품연구센터 2000 석재연 논문집 Vol.5 No.-

본 연구는 1993년부터 춘천시 신동면 형돌리 산 62번지 내에서 흑운모 화강암 및 편마암 암석을 원자재로 사용하여 건설기초재료인 쇄설골재 및 인공모래를 생산하는 업체로부터 제품 생산 후 발생하는 토양 스러치 케익이 연간 약 10만 입방정도 발생한다는 사실에 기초하여 석산에서 채취된 페잔토(석분)의 화학적, 물리적, 역학적 특성을 조사하여 석분의 이용 가능성을 확인하기 위한 실험으로 단위 시멘트량을 400kg, 잔골재율을 45% 그리고 물-시멘트비를 65%로 고정하고 잔골재 중 석분을ㄹ 0%, 10%, 20%, 30%, 40%, 50% 및 60%로 치환하여 제조된 콘크리트의 기초적 성질을ㄹ 시험하였다. 그 결과 석분의 치환율이 높을 수록 공기량은 증가하고 슬럼프값이 감소하였는데 이는 미세한 입자인 석분을 잔골재의 일부로 치환함으로써 비표면적이 증가하였기 때문인 것으로 사료된다. 압축강도와 휨강도는 모두 석분의 치환율이 증가할수록 압축강도와 휨강도는 다소 감소하는 경향을 나타냈으나 큰 성능차이는 보이지 않는 다는 것을 알 수 있었다. 이상의 실험을 통해 석분을 시멘트 콘크리트에 사용했을 경우 약간의 성능저하는 있지만 잔골재로의 활용이 가능하다는 것을 알 수 있었다. 그러므로 앞으로 건조수축, 균열, 크리이프 특성 및 내구성에 과한 연구가 더욱 심도있게 이루어져야 폐자원인 석분의 이용이 가능하리라 판단된다. This study aims to make cement concrete using crushed stone fines which are produced at Chuncheon city, Hyuldongri and find it's applications. According to the experimental results, when ratio of crushed stone fines was increased, air contents were increased and slump values were decreased. Also, the compressive strength and flexural strength were decreased when ration of crushed stone fines was increased. Although these strengths are decreased, the crushed stone fines can be used to construction materials because the decreased amounts are not so much.

금강하구 해양퇴적에 관한 연구

이길영,지윤식,한천규 대전대학교 산업기술연구소 2000 산업기술연구소 論文集 Vol.11 No.1

In this study, we discussed littroal movement and sedimentation of Keum-river estuary and estmated of deposition capacity. Keum-river estuary sea wall was constructed in 1988 Jan. and the sluice gate was completely closed in 1995 May. At the present, Kun-Jang new port. South and North jetty, Semankume sea wall and Kun-Jang industry estate are developing the Kume-river estuary around. At this developing and construction of Keum-river estaury, in many element of hydrauli - ocean waves, tide, tidal prism and depth of water - have changed. Tide analysis used statistics-analysis and harmonic-analysis from 1984 to 1997. Depth of water analysis used bathymetric chart from 1985 to 1997. Therefore we must correctly decise hydraulic element that is use simulation numerical test and hydraulic model. We analyze ocean waves, tide, tidal prism and depth of water change and modeling bed-load movement simulation; K-Cytengel, suspending-load deposition simulation; DIMOS-IV. Through the K-Cytengel and DIMOS-IV simulation estemated the sedimentation capacity and propose suitable answering such as dredging, water injection and remove of estuary sea wall.

유사학과 조정 및 교양교과과정개편에 관한 연구

이종범,김규연,전지용,이춘의,홍석주 朝鮮大學校 1995 교과교육연구 Vol.17 No.-