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Xiao-Dong Li,Jing Zhou,Rui Li,Bingjun Zhang,Yuge Wang,Xiaonan Zhong,Yaqing Shu,Yanyu Chang,Wei Qiu 대한신경과학회 2022 Journal of Clinical Neurology Vol.18 No.4
Background and Purpose Patients presenting with clinical characteristics that are strongly suggestive of neuromyelitis optica spectrum disorders (NMOSD) have a high risk of developing definite NMOSD in the future. Little is known about the clinical course, treatment, and prognosis of these patients with likely NMOSD at disease onset. Methods This study prospectively recruited and visited 24 patients with the limited form of NMOSD (LF-NMOSD) at disease onset from November 2012 to June 2021. Their demographics, clinical course, longitudinal aquaporin-4 immunoglobulin G (AQP4-IgG) serology, MRI, therapeutic management, and outcome data were collected and analyzed. Results The onset age of the cohort was 38.1±12.0 years (mean±standard deviation). The median disease duration was 73.5 months (interquartile range=44.3–117.0 months), and the follow-up period was 54.2±23.8 months. At the end of the last visit, the final diagnosis was categorized into AQP4-IgG-seronegative NMOSD (n=16, 66.7%), AQP4-IgG-seropositive NMOSD (n=7, 29.2%), or multiple sclerosis (n=1, 4.2%). Seven of the 24 patients (29.2%) experienced conversion to AQP4-IgG seropositivity, and the interval from onset to this serological conversion was 37.9±21.9 months. Isolated/mixed area postrema syndrome (APS) was the predominant onset phenotype (37.5%). The patients with isolated/mixed APS onset showed a predilection for conversion to AQP4-IgG seropositivity. All patients experienced a multiphasic disease course, with immunosuppressive therapy reducing the incidence rates of clinical relapse and residual functional disability. Conclusions Definite NMOSD may be preceded by LF-NMOSD, particularly isolated/ mixed APS. Intensive long-term follow-up and attack-prevention immunotherapeutic management is recommended in patients with LF-NMOSD.
Yanyu Chen,Xiao Wang,Huaijun Lin,Florian Vogel,Wei Li,Lin Cao,Zhidan Lin,Peng Zhang 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.119 No.-
A simple and efficient method for disposing of waste low-density polyethylene (LDPE) express packagingbags is proposed in this paper as a way to minimize waste and address the energy shortage at the sametime. In addition to following the production of carbon nanotubes (CNTs) derived from LDPE, the applicationof CNTs as electrodes for supercapacitors was attempted. Waste LDPE bags were pyrolyzed andcarbonized with catalyst using a dual-temperature reaction system, a designed 450 C pyrolysis temperatureaccompany with different carbonization temperatures (650 C, 700 C, 750 C, 800 C, 850 C), andtreatment durations (0 h, 2 h, 4 h, 6 h) were investigated. As determined by FE-SEM and FE-TEM, the CNTssynthesized at 750 C showed a finer tube diameter, much more uniform distribution, bamboo-like structure,as well as the highest yield of 41.9 %, and carbon conversion of 61.2 %. As being charged and discharged10,000 times, the electrode remained a 93.16 % capacitance and a 92.85 % Coulomb efficiency. A dual-temperature reaction system could be utilized to recycle waste LDPE efficiently, and the LDPEderivedCNTs could be applied for supercapacitors.
Kequan Zhang,Qian Fang,Yihan Xie,Yujia Chen,Tong Wei,Yanyu Xiao 대한환경공학회 2022 Environmental Engineering Research Vol.27 No.6
Polyhydroxyalkanoate (PHA) is a new type of bio-polyester which is expected to replace traditional petroleum-based plastics. The experiment was carried out based on anaerobic-microaerobic process. Firstly, the PHA accumulation capacity of activated sludge under different pH conditions was discussed, and then the batch test of nitrogen and phosphorus limitation was carried out under the condition of optimal pH. Moreover, the content of PHA monomer under nutrient restriction was also studied. The experimental results showed that when pH was not controlled (7.5~8.5), C:N and C:P weight ratio was equal to 150, the maximum content of PHA accounted for 50.39% and 36.07% of the dry cell weight, respectively. Besides, it was found that increasing the C:N weight ratio was beneficial to increasing the proportion of polyhydroxyvalerate (PHV) monomer in PHA.