http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Yang Kepeng (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
-
Fang Ting,Liu Suyi,Chen Liying,Ren Yating,Lu Dingqi,Yao Xinyi,Hong Tao,Zhang Xvfeng,Xie Zhimin,Yang Kepeng,Wang Xinchang 한국유전학회 2023 Genes & Genomics Vol.45 No.9
Background As a multisystemic autoimmune illness, the basic mechanisms behind the pathophysiology of systemic lupus erythematosus (SLE) remain poorly understood. Objective We aimed to investigate the possible significance of SLE’s DNA methylation and gain further insight into potential SLE-related biomarkers and therapeutic targets. Methods We used whole genome bisulfite sequencing (WGBS) method to analyze DNA methylation in 4 SLE patients and 4 healthy people. Results 702 differentially methylated regions (DMRs) were identified, and 480 DMR-associated genes were annotated. We found the majority of the DMR-associated elements were enriched in repeat and gene bodies. The top 10 hub genes identified were LCK, FYB, PTK2B, LYN, CTNNB1, MAPK1, GNAQ, PRKCA, ABL1, and CD247. Compared to the control group, LCK and PTK2B had considerably decreased levels of mRNA expression in the SLE group. Receiver operating characteristic (ROC) curve suggested that LCK and PTK2B may be potential candidate biomarkers to predict SLE. Conclusions Our study improved comprehension of the DNA methylation patterns of SLE and identified potential biomarkers and therapeutic targets for SLE.
-
Effects of Turbulent Dispersion on Water Droplet Impingement Based on Statistics Method
Ke Peng,Tang Xing,Lu Yi,Yang Hui Yun 한국항공우주학회 2018 International Journal of Aeronautical and Space Sc Vol.19 No.2
Researchonthewaterdropletmotionandimpactonsurfaceisthebasisofaircrafticingpredictionanddesignoficeprotection system. First, a new computational method based on statistical theory was developed in the Euler–Lagrange framework to calculatethelocalwaterimpingementcoefficientonthesurface,whichcouldbeusedtostudytheeffectofturbulentdispersion onthewaterdropletmotionandimpingementcharacteristics.Second,basedontheRANSmodelfortheairflowfield,taking engineconesurfacewithorwithoutslotasexamples,theinfluenceofturbulentdispersiononthewaterimpingementcoefficient on the surface was comparatively analyzed with the discrete random walk model. For the cone without film slot, turbulence causes a little impact on water droplet impingement. However, for the slotted cone, water droplet collection calculation must consider the effect of turbulence due to the stronger turbulence induced by the jet air. Further studies show that the effect is enhanced with the decrease of water droplet diameter. Finally, discussion about turbulent effects was proposed. This researchabout theinfluence ofturbulentdispersionwillbehelpfultoimprovetheaccuracy ofthewaterdropletimpingement calculation for some complex geometries.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
