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Wen Yating,Wang Xiaobin,Huang Jingyi,Li Yu,Li Tao,Ren Baozeng 한국탄소학회 2023 Carbon Letters Vol.33 No.4
The development of functional carbon materials using waste biomass as raw materials is one of the research hotspots of lithium-sulfur batteries in recent years. In this work, used a natural high-quality carbon source—coffee grounds, which contain more than 58% carbon and less than 1% ash. Honeycomb-like S and N dual-doped graded porous carbon (SNHPC) was successfully prepared by hydrothermal carbonization and chemical activation, and the amount of thiourea used in the activation process was investigated. The prepared SNHPC showed excellent electrochemical energy storage characteristics. For example, SNHPC-2 has a large pore volume (1.85 cm3·g−1), a high mesoporous ratio (36.76%), and a synergistic effect (S, N interaction). As the cathode material of lithium-sulfur batteries, SNHPC-2/S (sulfur content is 71.61%) has the highest specific capacity. Its initial discharge-specific capacity at 0.2 C is 1106.7 mAh·g−1, and its discharge-specific capacity after 200 cycles is still as high as 636.5 mAh·g−1.
Fang Ting,Liu Suyi,Chen Liying,Ren Yating,Lu Dingqi,Yao Xinyi,Hong Tao,Zhang Xvfeng,Xie Zhimin,Yang Kepeng,Wang Xinchang 한국유전학회 2023 Genes & Genomics Vol.45 No.9
Background As a multisystemic autoimmune illness, the basic mechanisms behind the pathophysiology of systemic lupus erythematosus (SLE) remain poorly understood. Objective We aimed to investigate the possible significance of SLE’s DNA methylation and gain further insight into potential SLE-related biomarkers and therapeutic targets. Methods We used whole genome bisulfite sequencing (WGBS) method to analyze DNA methylation in 4 SLE patients and 4 healthy people. Results 702 differentially methylated regions (DMRs) were identified, and 480 DMR-associated genes were annotated. We found the majority of the DMR-associated elements were enriched in repeat and gene bodies. The top 10 hub genes identified were LCK, FYB, PTK2B, LYN, CTNNB1, MAPK1, GNAQ, PRKCA, ABL1, and CD247. Compared to the control group, LCK and PTK2B had considerably decreased levels of mRNA expression in the SLE group. Receiver operating characteristic (ROC) curve suggested that LCK and PTK2B may be potential candidate biomarkers to predict SLE. Conclusions Our study improved comprehension of the DNA methylation patterns of SLE and identified potential biomarkers and therapeutic targets for SLE.