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Sen, Volkan,Bozkurt, Ozan,Demir, Omer,Tuna, Burcin,Yorukoglu, Kutsal,Ellidokuz, Hulya,Mungan, Ugur Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.24
Background: Possible roles of nestin expression in terms of predicting intravesical BCG therapy response in T1 high grade bladder cancer patients were investigated. Materials and Methods: T1 high grade bladder cancer patients who were treated with intravesical BCG between 1990-2009 were included. Immunohistochemical staining for nestin expression was performed. Nestin(+) and nestin(-) patients were compared in terms of recurrence and progression rates. Results: Sixty-three patients were included and median follow-up time was twenty-five months. After staining; 33 patients (52.4%) were classified as nestin (+) and 30 (47.6%) as (-). Nestin (+) patients were more likely to recur compared to nestin (-) patients (60.6% vs. 30%, p<0.05). Progression rates were also higher in nestin (+) patients, although this result did not reach statistical significance (15.2 % vs. 10 %, p=0.710). Conclusions: Nestin expression, which seems effective in predicting recurrence, appears to have a potential role in the urothelial carcinoma tumorigenesis. Patients with high grade bladder cancer and positive nestin expression need close follow-up and might be informed about more tendency to recur. Further comprehensive studies including larger patient cohorts may clarify the role of nestin in bladder cancer.
Construction Equipment Selection through Scenario-Based FDEA: Truck-Mixer Drums
Serdar Ulubeyli,Volkan Arslan,Ozer Uygun,Ismail Hakki Demir 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.8
This study aims to select the most suitable truck-mixer drum (TMD) for construction firms and to present a scenario-based approach to the construction equipment selection problem through the fuzzy data envelopment analysis (FDEA). The technical data of TMDs for quantitative criteria were initially obtained from three TMD companies operating in Turkey. A semi-structured questionnaire survey was then applied to 90 users (i.e., ready-mixed concrete companies) of these TMD brands for qualitative criteria. A scenario analysis, including four different scenarios, was lastly carried out by using FDEA. Considering each scenario, the best alternative was identified for TMD buyers. This study may be beneficial for researchers who can investigate (i) the decision-making process in the domain of the construction equipment selection and (ii) selection criteria of TMDs. This study may also help both potential buyers to make proper equipment selection decisions and TMD manufacturers to improve their products and competitiveness. In terms of originality, the study is first to focus on the selection process and criteria of TMDs. Similarly, FDEA was utilized for the first time in a construction equipment selection problem. As a limitation, the number of respondents, criteria, and alternatives might be increased to reveal more robust solutions.
( Cihan Comba ),( Sakir Volkan Erdogan ),( Aliye Erdogan ),( Aysenur Bagdatli ),( Busra Seker Atas ),( Omer Demir ),( Isa Aykut Ozdemir ) 대한산부인과학회 2021 Obstetrics & Gynecology Science Vol.64 No.6
Objective The authors present a surgical film for vulvar cancer surgery, which was performed via video endoscopy. Methods An 88-yearold woman with squamous cell carcinoma of the vulva and who underwent radical vulvectomy was treated with sentinel lymph node (SLN) and bilateral inguinofemoral lymphadenectomy, which is preferably performed via video endoscopic surgery with a near-infrared fluorescence video endoscopy system. SLN mapping was performed using indocyanine green and near-infrared fluorescence mapping. Results SLNs were detected in the left superficial inguinal area. The surgeons performed bilateral inguinofemoral lymphadenectomy. Conclusion No postoperative early or late complications developed, and the patient was discharged 7 days after surgery. Stage 1B vulvar cancer was identified.
( Cihan Comba ),( Gökhan Demirayak ),( Sakir Volkan Erdogan ),( Ibrahim Karaca ),( Omer Demir ),( Oguz Guler ),( Isa Aykut Ozdemir ) 대한산부인과학회 2020 Obstetrics & Gynecology Science Vol.63 No.4
Objective Colposcopic biopsy is a discomfortable procedure. Additionally, it creates negative influence on sexuality. This study aimed to investigate the relationships among tenaculum, pain perception, and biopsy size during colposcopy. Methods In total, 228 patients who underwent colposcopy-directed biopsy were included, and randomized into 4 groups based on whether analgesic and tenaculum were used and replaced (tenaculum with n=58/without analgesic n=56, no tenaculum replacement with n=57/without analgesic n=57). Lidocaine hydrochloride (40 mg) plus adrenaline (0.025 mg) was administered in the analgesic groups. The pain was assessed using a linear visual analog scale. The biopsy specimen size was measured in millimeters. Results The mean age of the patients was 42.85±8.88 years. The most frequent colposcopy indications were atypical squamous cells of undetermined significance and human papilloma virus-positive results on cervical cytology (30.2%; n=69). Low- and high-grade intraepithelial lesions were noted in 14.91% (n=34) and 10.96% (n=25) women through colposcopy-directed biopsy results, respectively. Tenaculum replacement increased pain perception in the without analgesic group; however, no statistically significant differences were noted between of the groups with and without tenaculum replacement with analgesic. The size and number of biopsy specimens were not associated with tenaculum replacement and analgesic use. Conclusion Administration of analgesics decreased discomfort and pain in patients. Tenaculum replacement aided colposcopists in manipulating the cervix. Additionally, administration of analgesics relieved pain in the tenaculum replacement group.
Nizamoglu, S.,Sari, E.,Jong-Hyeob Baek,In-Hwan Lee,Volkan Demir, H. IEEE 2009 IEEE journal of selected topics in quantum electro Vol.15 No.4
<P>LEDs made of In<SUB>x</SUB>Ga<SUB>1-x</SUB>N and (Al<SUB>x</SUB>Ga<SUB>1-x</SUB>)<SUB>1-y</SUB>In<SUB>y</SUB>P suffer from significantly reduced quantum efficiency and luminous efficiency in the green/yellow spectral ranges. To address these problems, we present the design, growth, fabrication, hybridization, and characterization of proof-of-concept green/yellow hybrid LEDs that utilize radiative and nonradiative [Forster resonance energy transfer (FRET)] energy transfers in their colloidal semiconductor nanocrystals (NCs) integrated on near-UV LEDs. In our first NC-LED, we realize a color-converted LED that incorporate green-emitting CdSe/ZnS core/shell NCs (lambda<SUB>PL</SUB> = 548 nm) on near-UV InGaN/GaN LEDs (lambda<SUB>EL</SUB> = 379 nm). In our second NC-LED, we implement a color-converted FRET-enhanced LED. For that, we hybridize a custom-design assembly of cyan- and green-emitting CdSe/ZnS core/shell NCs (lambda<SUB>PL</SUB> = 490 and 548 nm) on near-UV LEDs. Using a proper mixture of differently sized NCs, we obtain a quantum efficiency enhancement of 9% by recycling trapped excitons via FRET. With FRET-NC-LEDs, we show that it is possible to obtain a luminous efficacy of 425 lm/W opt and a luminous efficiency of 94 lm/W, using near-UV LEDs with a 40% external quantum efficiency. Finally, we investigate FRET-converted light-emitting structures that use nonradiative energy transfer directly from epitaxial quantum wells to colloidal NCs. These proof-of-concept demonstrations show that FRET-based NC-LEDs hold promise for efficient solid-state lighting in green/yellow.</P>