http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : UNO Naoki (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
-
Masaya Uno,Rie Matsuo,Naoki Maezawa,Tomoyasu Kato 대한산부인과학회 2023 Obstetrics & Gynecology Science Vol.66 No.4
Objective We evaluated the usefulness of human epididymis protein 4 (HE4), a tumor marker, during and after treatment in patients with ovarian cancer (OC). Methods We included Japanese patients newly diagnosed with OC treated at the National Cancer Center Hospital between 2014 and 2021. The HE4 levels were measured in the serum stored during diagnosis. To evaluate the concordance between HE4 and the imaging results, we employed sequential pairs of blood sampling points and the results of imaging examinations. We compared the timing of the elevated HE4 levels, imaging diagnoses, and elevated cancer antigen 125 (CA125) levels in patients with recurrence. The Ethics Review Committee of our institution (2021-056) reviewed this study. Results Forty-eight patients with epithelial OC were eligible for enrollment. The sensitivity, specificity, and positive and negative predictive values of HE4 (criterion, 70 pmol/L) for disease progression during the follow-up period were 79.4%, 59.1%, 32.5%, and 92.0%, respectively (time point, n=317). We evaluated the relationship between HE4 and CA125 variability and disease status (recurrence or no recurrence). For recurrence, the sensitivity and negative predictive value of HE4 (criterion, 70 pmol/L), CA125 (criterion, 35 U/mL), and combination of HE4 and CA125 were 77.8%, 85.2%, and 92.6% and 75.0%, 82.6%, and 88.9%, respectively (n=48). Among the 27 patients who exhibited recurrence, 16 and nine showed earlier increased HE4 levels than the relevant imaging and CA125 levels, respectively. Conclusion HE4 may be a valuable marker for follow-up during and after OC therapy. A complementary role for HE4 and CA125 measurements was suggested for follow-up observations.
-
Benefits of the activity of jointly reading picture books at home on upbringing of children
NAKAMOTO Mio,UNO Naoki,ISHII Yasuka,HIGUCHI Mawaharu 아시아아동지원학회 2012 아시아아동지원연구 Vol.3 No.-
The present study uses KH Corder2.x to analyze the notes of parents in "picture notebooks" of class for 2 years children at M Nursery School that has implemented this system as a part of daily childcare activity. From the results of this analysis , it came out that the other persons involved reading activity at home were diverse, and in children as well the other persons the reading activity engendered various sentiments arising from feelings of “like" and “like very much". Moreover, it also came to light that both parents and children proactively participated in the activity of reading together, and without restricting to reading activity, it expanded to several activities. From these results , we came to know that the activity of reading using picture books as a medium is not a unidirectional activity, rather it has mutual effects of joint reading, and once started, it significantly impact the upbringing of children. Moreover, apart from parents, sharing of feelings, words, space, behavior etc. emerging from the “person" and enjoying while jointly reading the picture books supports the growth and development of children, and creates even better environment for their upbringing.
-
( Shino Shimura ),( Norihisa Ishimura ),( Hironobu Mikami ),( Eiko Okimoto ),( Goichi Uno ),( Yuji Tamagawa ),( Masahito Aimi ),( Naoki Oshima ),( Shuichi Sato ),( Shunji Ishihara ),( Yoshikazu Kinosh 대한소화기기능성질환·운동학회 2016 Journal of Neurogastroenterology and Motility (JNM Vol.22 No.1
Background/Aims Small intestinal bacterial overgrowth (SIBO) is considered to be involved in the pathogenesis of functional gastrointestinal disorders (FGID). However, the prevalence and clinical conditions of SIBO in patients with FGID remain to be fully elucidated. Here, we examined the frequency of SIBO in patients with refractory FGID. Methods We prospectively enrolled patients with refractory FGID based on Rome III criteria. A glucose hydrogen breath test (GHBT) was performed using a gas analyzer after an overnight fast, with breath hydrogen concentration measured at baseline and every 15 minutes after administration of glucose for a total of 3 hours. A peak hydrogen value ≥ 10 ppm above the basal value between 60 and 120 minutes after administration of glucose was diagnosed as SIBO. Results A total of 38 FGID patients, including 11 with functional dyspepsia (FD), 10 with irritable bowel syndrome (IBS), and 17 with overlapping with FD and IBS, were enrolled. Of those, 2 (5.3%) were diagnosed with SIBO (one patient diagnosed with FD; the other with overlapping FD and IBS). Their symptoms were clearly improved and breath hydrogen levels decreased to normal following levofloxacin administration for 7 days. Conclusions Two patients initially diagnosed with FD and IBS were also diagnosed with SIBO as assessed by GHBT. Although the frequency of SIBO is low among patients with FGID, it may be important to be aware of SIBO as differential diagnosis when examining patients with refractory gastrointestinal symptoms, especially bloating, as a part of routine clinical care. (J Neurogastroenterol Motil 2016;22:60-68)
KCI
KISS연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
