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      • KCI등재

        A Study on the Characteristics of Contemporary Chinese Painting from Micro Perspective

        Tian Yuan 국제문화기술진흥원 2024 International Journal of Advanced Culture Technolo Vol.12 No.1

        Contemporary Chinese "micro-perspective" painting is an artistic phenomenon that we cannot ignore. It is the young artists who focus on themselves and their communities, record their stories and emotions in their life fragments into the coming history, and diary paintings as "micro-perspective" paintings allow "marginal people" to find their place. Based on the analysis of the aesthetic form and aesthetic characteristics of Chinese contemporary art, this paper explores the three aesthetic dimensions and their inherent aesthetic value, and explains its significance from the perspective of "micro-view" aesthetics. In the contemporary context, "micro-perspective" painting has become a unique cultural phenomenon, a consciousness situation. However, this phenomenon has a very unique artistic value and cultural value for the youth art group and even the formation of aesthetic culture and zeitgeist in China's current society.

      • Liposome-mediated Induction of Apoptosis of Human Hepatoma Cells by C-Myc Antisense Phosphorothioate Oligodeoxynucleotide and 5-Fluorouracil

        Yuan, Yuan,Cai, Hui,Yang, Xiao-Jun,Li, Wei,He, Jin,Guo, Tian-Kang,Chen, Yi-Rong Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.14

        Background: The aim of this study was to investigate the effect of a c-myc antisense oligodeoxynucleotide and 5-fluorouracil on the expression of c-myc, invasion and proliferation of HEPG-2 liver cancer cells. Materials and Methods: HEPG-2 cells were treated with lipiosome-mediated c-myc ADSON and 5-fluorouracil. The proliferation inhibition rate and invasion were measured by MTT and invasion assay, respectively. Cell apoptosis was detected by flow cytometry and expression of c-myc by RT-PCR and immunohistochemistry. Results: The proliferation inhibition rate was significantly higher in the antisense oligodeoxynucleotide added-5-fluorouracil group than single antisense oligodeoxynucleotide or 5-fluorouracil group (p<0.05). G0/G1 cells in the antisense oligodeoxynucleotide group and S cells in the 5-fluorouracil groups were significantly increased than that in the control group, respectively (P<0.01). The amplification strips of PCR products in 5-FU, ASODN and combination groups were significantly weaker than that in the control group (P<0.01). The percentage of c-myc-protein-positive cells were significantly lower in antisense oligodeoxynucleotide, 5-fluorouracil and combination groups than that in the control group (P<0.01). Conclusions: A liposome-mediated c-myc antisense oligodeoxynucleotide and 5-fluorouracil can inhibit the proliferation and invasion of liver cancer cells by reducing the expression of c-myc. A c-myc antisense oligodeoxynucleotide can increase the sensitivity of liver cancer cells to 5-fluorouracil and decrease the dosage of the agent necessary for efficacy, providing an experimental basis for the clinical therapy of liver cancer.

      • KCI등재

        State-dependent Impulsive Control for Consensus of Multi-agent Systems

        Yuan Tian,Chuandong Li 제어·로봇·시스템학회 2021 International Journal of Control, Automation, and Vol.19 No.12

        This paper aims to investigate the consensus of multi-agent systems, where each agent runs hopfied-type neural networks, by means of the state-dependent impulsive control. The challenge comes from the fact that the occurrence of impulse varies according to the state of the agent, which means it is hard to predict when an impulse occurs. To solve this problem, we try to transform the impulsive system from state-dependent to fixed-time. In order to do that, we first construct a global consensus error state-dependent with a multi-agent system according to the impulsive consensus protocol. Then we use the B-equivalence method to form a comparison impulsive system of fixed-time impulsive sequence. Using Lyapunov stability theory, we prove that these two systems have the same stability. So we establish sufficient consensus conditions of multi-agent system by analyzing the comparison system. We perform extensive evaluations to validate the correctness of theoretical results and the effectiveness of the statedependent impulsive consensus protocol.

      • Using Frequency Scaling on Virtualized Memory in Cloud Datacenters

        Yuan Tian,Ze Xiao 보안공학연구지원센터 2016 International Journal of Grid and Distributed Comp Vol.9 No.9

        As the increasing of IT-infrastructure in cloud platforms, rapidly growth of energy consumption becomes a critical problem in many cloud datacenters. Conventionally, most of studies on energy-efficiency optimization concentrate on CPU related energy costs instead of memory subsystem, since CPU often dominates the total energy consumption in modern servers. However, such a situation is gradually changing as more and more cloud datacenters are equipped with larger and larger memory systems for dealing with data-intensive applications. In this paper, we present a novel mechanism, namely frequency scaling on virtualized memory (FSVM), which applies DVFS technology on memory subsystem based on the characteristics of active VM instances. Comparing with previous studies, our approach provides a fine-grained memory energy consumption conservation mechanism for virtualized servers. Extensive experiments are conducted to investigate the effectiveness and performance of our FSVM, and the results indicate that it can significantly improve the energy-efficiency of memory subsystem in virtualized servers.

      • OK-432 Suppresses Proliferation and Metastasis by Tumor Associated Macrophages in Bladder Cancer

        Tian, Yuan-Feng,Tang, Kun,Guan, Wei,Yang, Tao,Xu, Hua,Zhuang, Qian-Yuan,Ye, Zhang-Qun Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.11

        OK-432, a Streptococcus-derived anticancer immunotherapeutic agent, has been applied in clinic for many years and achieved great progress in various cancers. In the present study, we investigated its anticancer effect on bladder cancer through tumor associated macrophages (TAMs). MTS assay validated OK-432 could inhibit proliferation in both T24 and EJ bladder cell lines. OK-432 also induced apoptosis of bladder cancer cells in vitro. Consequently, we demonstrated that OK-432 could suppress the bladder cancer cells migration and invasion by altering the EMT-related factors. Furthermore, using SD rat model, we revealed that OK-432 inhibited tumor growth, suppressed PCNA expression and inhibited metastasis in vivo. Taken together, these findings strongly suggest that OK-432 inhibits cell proliferation and metastasis through inducing macrophages to secret cytokines in bladder cancer.

      • KCI등재

        Role of folP1 and folP2 Genes in the Action of Sulfamethoxazole and Trimethoprim Against Mycobacteria

        ( Tian Zhou Liu ),( Bang Xing Wang ),( Jin Tao Guo ),( Yang Zhou ),( Mugweru Julius ),( Moses Njire ),( Yuan Yuan Cao ),( Tian Wu ),( Zhi Yong Liu ),( Chang Wei Wang ),( Yong Xu ),( Tian Yu Zhang ) 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.9

        The combination of trimethoprim (TMP) and sulfamethoxazole (SMX) has been shown to be active against Mycobacterium tuberculosis (Mtb) in clinical tuberculosis (TB) treatment. However, the mechanism of action of TMP-SMX against Mtb is still unknown. To unravel this, we have studied the effect of TMP and SMX by deleting the folP2 gene in Mycobacterium smegmatis (Msm), and overexpressing the Mtb and Msm folP1/2 genes in Msm. Knocking out of the folP2 gene in Msm reduced the minimum inhibitory concentration of SMX 8-fold compared with wild type. Overexpression of the folP1 genes from Mtb and Msm increased the MICs by 4- and 2-fold in Msm for SMX and TMP, respectively. We show a strong correlation between the expression of folP1 and folP2 genes and TMP-SMX resistance in mycobacteria. This suggests that a combination of FolP2 inhibitor and SMX could be used for TB treatment with a better outcome.

      • KCI등재

        Identification and characterization of CONSTANS-like genes from Curcuma alismatifolia

        Yuan-Yuan Li,Xiao-Huang Chen,Hui-Wen Yu,Qi-Lin Tian,Luan-Mei Lu 한국원예학회 2021 Horticulture, Environment, and Biotechnology Vol.62 No.2

        The CONSTANS ( CO ) and CONSTANS - like ( COL ) genes have an important role in the regulation of fl owering in photoperiod-sensitive plants. However, information on the molecular characterization of COL genes in Curcuma alismatifoliais very limited. The objective of this study was to identify and evaluate 8 COL homologs ( CaCOLs ) in the C. alismatifoliatranscriptome. Their structures, phylogenetic relationships and expressing patterns under short-day (SD) and long-day (LD)contexts were investigated. Our results showed that CaCOLs were classifi ed into three groups: CaCOL3 and CaCOL6 in groupI were the most CO - like genes; CaCOL7 and CaCOL8 in group II contains only one B-box; CaCOL1 to 2 and CaCOL4 to 5formed the group III. Phylogenetic analysis of the CaCOLs in Arabidopsis, Rice, Barley, Malaccensis and C. alismatifoliademonstrated that both the B-box and CCT domains were conserved in dicot and monocot plants, but diff erent groups ofCOL genes evolved independently. Diff erent patterns of mRNA accumulation in C. alismatifolia leaves in response to SDand LD treatments were observed. CaCOL1 , CaCOL2 , CaCOL4 and CaCOL7 showed signifi cantly higher expressions inLD treatment than that of SD, indicating that they were potential fl owering inducers, and are candidate genes for research infl owering regulation and circadian controlling in C. alismatifolia plants. Altogether, our study facilitates successful regulationof fl owering in Curcuma species and provides insights for future molecular breeding programs.

      • KCI등재

        454 Pyrosequencing Analysis of Bacterial Diversity Revealed by a Comparative Study of Soils from Mining Subsidence and Reclamation Areas

        ( Yuan Yuan Li ),( Long Qian Chen ),( Hong Yu Wen ),( Tian Jian Zhou ),( Ting Zhang ),( Xia Li Gao ) 한국미생물 · 생명공학회 2014 Journal of microbiology and biotechnology Vol.24 No.3

        Significant alteration in the microbial community can occur across reclamation areas suffering subsidence from mining. A reclamation site undergoing fertilization practices and an adjacent coal-excavated subsidence site (sites A and B, respectively) were examined to characterize the bacterial diversity using 454 high-throughput 16S rDNA sequencing. The dominant taxonomic groups in both the sites were Proteobacteria, Acidobacteria, Bacteroidetes, Betaproteobacteria, Actinobacteria, Gammaproteobacteria, Alphaproteobacteria, Deltaproteobacteria, Chloroflexi, and Firmicutes. However, the bacterial communities` abundance, diversity, and composition differed significantly between the sites. Site A presented higher bacterial diversity and more complex community structures than site B. The majority of sequences related to Proteobacteria, Gemmatimonadetes, Chloroflexi, Nitrospirae, Firmicutes, Betaproteobacteria, Deltaproteobacteria, and Anaerolineae were from site A; whereas those related to Actinobacteria, Planctomycetes, Bacteroidetes, Verrucomicrobia, Gammaproteobacteria, Nitriliruptoria, Alphaproteobacteria, and Phycisphaerae originated from site B. The distribution of some bacterial groups and subgroups in the two sites correlated with soil properties and vegetation due to reclamation practice. Site A exhibited enriched bacterial community, soil organic matter (SOM), and total nitrogen (TN), suggesting the presence of relatively diverse microorganisms. SOM and TN were important factors shaping the underlying microbial communities. Furthermore, the specific plant functional group (legumes) was also an important factor influencing soil microbial community composition. Thus, the effectiveness of 454 pyrosequencing in analyzing soil bacterial diversity was validated and an association between land ecological system restoration, mostly mediated by microbial communities, and an improvement in soil properties in coalmining reclamation areas was suggested.

      • KCI등재

        Assessment of Steel Slag and Steel Fiber to Control Electromagnetic Shielding in High-Strength Concrete

        Tian-Feng Yuan,Jin-Seok Choi,Seong-Kyum Kim,Young-Soo Yoon 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.3

        This study investigates the influence of steel slag (SS) and steel fibers on the electrical resistivity and electromagnetic (EM) shielding effectiveness of high-strength concrete (HSC). It was found that the electrical resistivity of mixtures were mainly influenced by free water. Thus, the EM shielding effectiveness was evaluated without the effect of free water. HSC with 20% replacement ratio of SS exhibited slightly improved EM shielding, lower electrical resistivity, and reduced strength (compressive and flexural) compared to HSC without SS. However, HSC with steel fibers exhibited significantly improved EM shielding, lower electrical resistivity, and higher strength and toughness compared to HSC without steel fibers. An increase in the steel fiber content in the HSC significantly decreased the electrical resistivity and increased the shielding effectiveness, strength, and toughness. Regardless of the fiber content in the fiber volume fraction of mixture, the shielding effectiveness is similar for cases with and without SS whose electrical resistivity values differ only slightly. This proves that the EM shielding effectiveness was mainly affected by the electrical resistivity and these properties are significantly correlated when the electrical resistivity values differ noticeably. HSC reinforced with rebar with 50 mm spacing exhibited a 23.5 − 75.6% increase in the shielding effectiveness in the 600 − 1,000 MHz frequency region compared to pristine HSC.

      • KCI등재

        HETEROGENEITY EFFECTS OF DEVELOPMENT FUNDING ON MICROENTERPRISES

        YUAN TIAN 중앙대학교 경제연구소 2015 Journal of Economic Development Vol.40 No.3

        This paper focuses on the heterogeneity of firm’s characteristics on development funding. It develops a theoretical model under utility maximization framework with imperfect insurance and credit markets constraints, deriving the returns to capital determined by firm’s size, structure and entrepreneur’s utility form. Empirical evidence from Sri Lanka Microenterprises Project (2005-2010) shows that the returns vary across different quantiles of firm’s profits and the ability/risk aversion of entrepreneur affects the returns significantly differently on the distribution of profits. It also summarizes the development funding policy and offers advice on policy evaluation in Sri Lanka.

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