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The phase transitions of hydrogen bonded ferroelectric CsH2PO4 under high pressure
Yuki Nakamoto,Kiyoshi Deguchi,Kouichi Tashima,Li Chung Ming,Shinji Azuma,Shoichi Endo,Takumi Kikegawa 한국물리학회 2005 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.46 No.1
Dielectric-constant measurements of a hydrogen-bonded crystal CsH2PO4 were carried out at low temperature (4 K < T < 300 K) under high pressure up to 3.0 GPa. By the dielectric measurements, we discovered two new high-pressure phases at about 1.3 GPa and 2.55 GPa, which are named as phases V and VI, respectively. These phases have a stable pressure region higher than that of the previously reported phase AFEII. On the other hand, at ambient temperature two phase transitions were previously found at 2.9 and 4.1 GPa through X-ray diraction study. However, we could not observe any anomaly corresponding to these phase transitions in the present dielectric measurement.
The Initial Enzyme for Glycosylphosphatidylinositol Biosynthesis Requires PIG-Y, a Seventh Component
Murakami, Yoshiko,Siripanyaphinyo, Uamporn,Hong, Yeongjin,Tashima, Yuko,Maeda, Yusuke,Kinoshita, Taroh American Society for Cell Biology 2005 Molecular biology of the cell Vol.16 No.11
<P>Biosynthesis of glycosylphosphatidylinositol (GPI) is initiated by an unusually complex GPI-N-acetylglucosaminyltransferase (GPI-GnT) consisting of at least six proteins. Here, we report that human GPI-GnT requires another component, termed PIG-Y, a 71 amino acid protein with two transmembrane domains. The Burkitt lymphoma cell line Daudi, severely defective in the surface expression of GPI-anchored proteins, was a null mutant of PIG-Y. A complex of six components was formed without PIG-Y. PIG-Y appeared to be directly associated with PIG-A, implying that PIG-Y is the key molecule that regulates GPI-GnT activity by binding directly to the catalytic subunit PIG-A. PIG-Y is probably homologous to yeast Eri1p, a component of GPI-GnT. We did not obtain evidence for a functional linkage between GPI-GnT and ras GTPases in mammalian cells as has been reported for yeast cells. A single transcript encoded PIG-Y and, to its 5′ side, another protein PreY that has homologues in a wide range of organisms and is characterized by a conserved domain termed DUF343. These two proteins are translated from one mRNA by leaky scanning of the PreY initiation site.</P>
進行乳癌에 대한 術後의 多劑·免疫·化學療法 : Fluorouracil. Doxorubicin Cyclophosphamide, BCG 백신
Buzdar, Aman U.,Blumenschein, George R.,Gutterman, Jordan,Tashima, Charles K.,Hortobagyi, Gabriel N.,Smith, Terry L.,Campos, Luis T.,Wheeler, Warren L.,Hersh, Evan M.,Freireich, Emil J.,Gehan, Edmund 藥業新聞社 1980 (月刊) 醫藥情報 Vol.1980 No.5
Yuki Tanisaka,Masafumi Mizuide,Akashi Fujita,Ryuhei Jinushi,Rie Shiomi,Takahiro Shin,Kei Sugimoto,Tomoaki Tashima,Yumi Mashimo,Shomei Ryozawa 대한소화기내시경학회 2024 Clinical Endoscopy Vol.57 No.2
Background/Aims: Endoscopic ultrasound-guided tissue acquisition (EUS-TA) using Franseen needles is reportedly useful for its high diagnostic yield. This study compared the diagnostic yield and puncturing ability of EUS-TA using 22-gauge cobalt-chromium (CO-Cr) needles with those of stainless-steel Franseen needles in patients with solid pancreatic lesions. Methods: Outcomes were compared between the 22-gauge Co-Cr Franseen needle (December 2019 to November 2020; group C) and stainless-steel needle (November 2020 to May 2022; group S). Results: A total of 155 patients (group C, 75; group S, 80) were eligible. The diagnostic accuracy was 92.0% in group C and 96.3% in group S with no significant intergroup differences (p=0.32). The rate of change in the operator (from training fellows to experts) was 20.0% (15/75) in group C and 7.5% (6/80) in group S. Stainless-steel Franseen needles showed less inter-operator difference than Co-Cr needles (p=0.03). Conclusions: Both Co-Cr and stainless-steel Franseen needles showed high diagnostic ability. Stainless-steel Franseen needles are soft and flexible; therefore, the range of puncture angles can be widely adjusted, making them suitable for training fellows to complete the procedure.
Yuki Tanisaka,Masafumi Mizuide,Akashi Fujita,Tomoya Ogawa,Hiromune Katsuda,Yoichi Saito,Kazuya Miyaguchi,Ryuhei Jinushi,Rie Terada,Yuya Nakano,Tomoaki Tashima,Yumi Mashimo,Shomei Ryozawa 소화기인터벤션의학회 2022 International journal of gastrointestinal interven Vol.11 No.1
Endoscopic retrograde cholangiopancreatography (ERCP) is the gold standard for diagnosis and intervention in patients with biliopancreatic disorders. However, ERCP in patients with surgically altered anatomy (SAA) is considered more difficult than in patients with normal anatomy. Since the introduction of balloon enteroscopes for patients with small intestine disorders, single-balloon enteroscopes (SBEs) and double-balloon enteroscopes (DBEs) have also been used for biliopancreatic diseases in patients with SAA. Nevertheless, the use of conventional SBEs and DBEs is limited, as a balloon enteroscope has a working length of 200 cm and a narrow working channel with a diameter of 2.8 mm; therefore, few ERCP accessories are available for use. A short-type SBE with a working length of 152 cm and a working channel of 3.2 mm in diameter, and a short-type DBE with a working length of 155 cm and a working channel of 3.2 mm were introduced to solve these difficulties. Favorable outcomes of these devices have recently been reported. Moreover, studies have reported several tips to achieve procedural success and factors affecting procedure failure. Difficult cases necessitate alternative techniques, such as percutaneous transhepatic biliary drainage and endoscopic ultrasound-guided biliary drainage.
Yuki Tanisaka,Masafumi Mizuide,Akashi Fujita,Tomoya Ogawa,Hiromune Katsuda,Yoichi Saito,Kazuya Miyaguchi,Ryuhei Jinushi,Rie Terada,Yuya Nakano,Tomoaki Tashima,Yumi Mashimo,Shomei Ryozawa 소화기인터벤션의학회 2022 Gastrointestinal Intervention Vol.11 No.1
Endoscopic retrograde cholangiopancreatography (ERCP) is the gold standard for diagnosis and intervention in patients with biliopancreatic disorders. However, ERCP in patients with surgically altered anatomy (SAA) is considered more difficult than in patients with normal anatomy. Since the introduction of balloon enteroscopes for patients with small intestine disorders, single-balloon enteroscopes (SBEs) and double-balloon enteroscopes (DBEs) have also been used for biliopancreatic diseases in patients with SAA. Nevertheless, the use of conventional SBEs and DBEs is limited, as a balloon enteroscope has a working length of 200 cm and a narrow working channel with a diameter of 2.8 mm; therefore, few ERCP accessories are available for use. A short-type SBE with a working length of 152 cm and a working channel of 3.2 mm in diameter, and a short-type DBE with a working length of 155 cm and a working channel of 3.2 mm were introduced to solve these difficulties. Favorable outcomes of these devices have recently been reported. Moreover, studies have reported several tips to achieve procedural success and factors affecting procedure failure. Difficult cases necessitate alternative techniques, such as percutaneous transhepatic biliary drainage and endoscopic ultrasound-guided biliary drainage.