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위암 환자에서 위아전절제술후 재건 방법에 따른 술후 체중 변화의 비교 연구
이승도(Sung Do Lee),신동훈(Dong Hoon Shin),최경현(Kyung Hyun Choi),백승언(Seung Uhn Baek),이충한(Choong Han Lee) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.6
N/A Weight. loss and malnutrition are common complications after subtotal gastrectomy. The authors campared weight changes, Visick grade and performance status according to reconstructing method after subtotal gastrectomy. The reconstruction methods were Roux-en-Y gastrojejunostomy and jejunojejenostomy (R-Y method) or Billorth-II gastrojejunostomy and Braun jejunojejunostomy (B-II method) after subtotal gastrectomy. The results were as follow; In stage I stomach cancer, weight recovery period were significantly decreased in R- Y method than B-II method in male and female. In stage llI stomach cancer, weight recovery period were no significant differences between R- Y method and B-II method in male and female. There were no significant differences in body weight change during 2 years after subtotal gastrectomy between R-Y method and B-II method in stage I and III stomach cancer. There were no significant differences in Visick grade and performance status during 2 years after subtotal gastrectomy between R - Y method and B- II method in stage I and III stomach cancer. Our conclusion was that weight reovery period was shortened in R-Y method than B-II method in stage I stomach cancer.
Seung-Hyun Lee,Hyun-Jeong Kang,Byung-Kwon Ahn,Sung-Uhn Baek,Hee-Kyung Chang,Nham-Gun Oh,Mee-Young Sol,Do-Youn Park 대한외과학회 2011 Annals of Surgical Treatment and Research(ASRT) Vol.80 No.2
Purpose: The purpose of this study is to identify useful clinicopathologic factors for the prediction of lymph node metastasis in submucosally invasive colorectal carcinoma. Methods: A total of fifty-four cases of colorectal carcinomas with submucosal invasion were included. The patients underwent curative resection with en bloc lymph node dissection. Clinical features such as age, gender, tumor size and tumor location were reviewed. Histopathologic examinations for tumor growth type, differentiation, depth of tumor invasion, lymphovascular invasion, neural invasion, tumor budding and peritumoral inflammation were performed. The expression of E-cadherin, β-catenin, Smad4, p53 and Ki-67 were examined by immunohistochemistry. The correlation between the clinicopathologic factors and lymph node metastasis was evaluated. Results: From the 54 patients with submucosally invasivecolorectal carcinoma, lymph node metastasis was identified in 13 cases (24.1%). The incidence of lymph node metastasis was significantly higher in cases positive for lymphovascular invasion (55.6% vs. 17.8%, P=0.028) and positive for tumor budding (47.4% vs. 11.45%, P=0.006). Cases negative for Smad4 had a higher tendency for incidence of lymph node metastasis (28.6% vs. 15.8%, P=0.341). Other clinicopathologic and immunohistochemical features were irrelevant to the lymph node status. In multivariate analysis, only tumor budding was an independent predictor of lymph node metastasis (P=0.051). Conclusion: Lymphovascular invasion and tumor budding were predictive factors of lymph node metastasis in submucosally invasive colorectal carcinoma. The incidence of lymph node metastasis of submucosally invasive colorectal carcinoma was not low. Careful selection for avoiding surgery in submuocally invasive colorectal carcinoma should be considered.