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황영선 ( Young-sun Hwang ),김기쁨 ( Gi-ppeum Kim ),안경근 ( Kyung-geun Ahn ),김선태 ( Sun Tae Kim ),윤원병 ( Won Byong Yon ),한원영 ( Won Young Han ),정명근 ( Myoung-gun Choung ) 한국환경농학회 2016 한국환경농학회 학술대회집 Vol.2016 No.-
The distribution and variation of the contents of targeted metabolites in soybean [Glycine max (L.) Merr.] seeds are affected by both genetic and environmental factors. In this study, the 192 soybean germplasm accessions collected from two provinces of Korea to elucidate the effects of seed coat color and 100 seeds dry weight on the metabolic variation and responses of targeted metabolites. The main and interaction effects of seed coat color and 100 seeds dry weight were present in sucrose, total oligosaccharides, total carbohydrates and all measured fatty acids. The targeted metabolites were clustered within three groups, 1) daidzein and genistein, 2) glycitein, protein, and linoleic acid, and 3) the rest of the targeted metabolites. These metabolites were not only differently related to 100 seeds dry weight, based on the difference of seed coat color by regression analyses but also responded differentially to seed coat color in principle component analysis(PCA) loading plots. The inter- relationship between the targeted metabolites was highly present in the result of correlation analysis. Overall, results revealed that the targeted metabolites were diverged in relation to seed coat color and 100 seeds dry weight within locally collected soybean seed germplasm accessions.
Effects of Galla chinensis extracts on UVB-irradiated MMP-1 production in hairless mice.
Sun, Zheng-wang,Hwang, Eunson,Lee, Hyun Ji,Lee, Tae Youp,Song, Hyun Geun,Park, Sang-Yong,Shin, Heon-Sub,Lee, Don-Gil,Yi, Tae Hoo Springer-Verlag Tokyo 2015 Journal of Natural Medicines Vol.69 No.1
<P>Galla chinensis (GAC) is a natural traditional Chinese medicine that has been widely used in folk medicine. Although GAC compounds (mainly gallic acid and methyl gallate) possess strong antiviral, antibacterial, anticancer, and antioxidant activities, there is no report regarding topical or oral administration of GAC compounds on UVB irradiation-induced photoaging in hairless mice (SKH: HR-1). In the present study, we examined cell viability, intracellular reactive oxygen species (ROS), matrix metalloproteinase-1 (MMP-1), and interleukin-6 (IL-6) in skin fibroblasts and keratinocytes induced by UVB in vitro. We also studied skin damage by measuring skin thickness, elasticity, wrinkling and levels of protein MMP-1, elastin, procollagen type I, and transforming growth factor-β1 (TGF-β1) in hairless mouse skin chronically irradiated by UVB in vivo. GAC treatment significantly prevented skin photoaging by reducing the levels of ROS, MMP-1, and IL-6 and promoting production of elastin, procollagen type I, and TGF-β1. According to the results of H&E staining and Masson's trichrome staining, GAC reduced skin thickness and wrinkle formation while it increased skin elasticity. The effects of GAC on UVB-induced skin photoaging may be due to suppressed MMP-1 expression. These findings could be referenced for the development of new agents that target UVB-induced photoaging.</P>
Identification of S Haplotypes in Commercial F1 Hybrid Cultivars of Radish by PCR-RFLP Analysis
Sun Hyoung Lim,Ki Taek Kim,Su Hyoung Park,Hwa Jin Cho,Han Yong Park,So Young Hwang,Moo Kyoung Yoon,Il Gin Mok,Jong Gyu Woo,Dae Geun Oh 한국육종학회 2006 한국육종학회지 Vol.38 No.3
Self incompatibility (SI) of Cruciferous crop has been studied not only to find out the evolution of the self incompat-ibility system, but also to identify the S haplotypes of the plant materials on the practical breeding programs. It has been reportedtha
Hwang, Eun Yeong,Park, Geun Ho,Lee, Chun Sun,Kang, Yi Young,Lee, Junseong,Lee, Bun Yeoul The Royal Society of Chemistry 2015 Dalton transactions Vol.44 No.8
<P>Post-metallocenes were constructed for olefin polymerization using 1,2,3,4,7,8,9,10-octahydro[1,10]-phenanthroline and 1,2,3,4-tetrahydro[1,10] phenanthroline derivatives. A series of zirconium complexes LZrCl2( NHMe2)(2) [L = 2,9-H-2-C12H12N2 (4), 2,9-Me-2-C12H12N2 (5), 2,9-nBu(2)-C12H12N2 (6), and 2,9-iPr(2-)C(12)H(12)N(2) (7)] -and hafnium complexes - LHfCl2(NHMe2)(2) [L = 2,9-H-2-C12H12N2 (8), 2,9-Me-2-C12H12N2 (9), 2,9-nBu(2)-C12H12N2 (10), and 2,9-iPr(2)-C12H12N2 (11)] -were synthesized via the reaction of octahydro [1,10]phenanthrolines (2,9-R-2-C12H12(NH)(2)) with (Me2N)(2)MCl2 (DME). The reaction of 2,9-R-2-C12H12(NH)(2) with (PhCH2)(2)ZrCl2 in the presence of a small amount of THF afforded a series of THF adduct analogs, i.e., LZrCl2(THF)(2) [L = 2,9-H-2-C12H12N2 (12), 2,9-Me-2-C12H12N2 (13), 2,9-nBu(2)-C12H12N2 (14), and 2,9-iPr(2)-C12H12N2 (15)]. The treatment of 12 and 13 with excess Me3Al resulted in the formation of unexpected complexes, i.e., (eta(4)-LAlMe2)ZrCl2(Me) [L = 2,9-H-2-C12H12N2 (16) and 2,9-Me-2-C12H12N2 (17)], in which the Me2Al unit forms a five-membered ring through binding with the two nitrogen donors and the MeCl2Zr unit slips to an. 4-binding mode containing the N-C-C-N fragment. The treatment of tetrahydro[ 1,10] phenanthrolines [2,9-R-2-C12NH9(NH)] with M(CH2Ph)(4) afforded tribenzyl zirconium complexes LZr(CH2Ph)(3)-[L = 2,9-Me-2-C12NH9N (18) and 2,9-nBu(2)-C12NH9N (19)] -and hafnium complexes - LHf(CH2Ph)(3) [L = 2,9-Me-2-C12NH9N (20), 2,9-nBu(2)-C12NH9N (21), and 2,9-iPr(2)-C12NH9N (22)]. The structures of 4, 5, 12, 17, and 22 were elucidated by X-ray crystallography. The newly prepared complexes were screened for ethylene/1-octene copolymerization activity: 12 and 16 were potent catalysts (activities of 74 x 106 g mol-Zr h(-1) at similar to 120 degrees C under 30 bar ethylene) for the production of wax-like low-molecular weight polyethylene (Mn: similar to 5000), which is widely used in industry.</P>
Distal hereditary motor neuropathy type 7B with Dynactin 1 mutation
Hwang, Sun Hee,Kim, Eun Ja,Hong, Young Bin,Joo, Jaesoon,Kim, Sung Min,Nam, Soo Hyun,Hong, Hyun Dae,Kim, Seung Hyun,Oh, Kiwook,Lim, Jeong-Geun,Cho, Jeong Hee,Chung, Ki Wha,Choi, Byung-Ok Spandidos Publications 2016 MOLECULAR MEDICINE REPORTS Vol. No.
PERMANENTS OF DOUBLY STOCHASTIC KITE MATRICES
Hwang, Suk-Geun,Lee, Jae-Don,Park, Hong-Sun Korean Mathematical Society 1998 대한수학회지 Vol.35 No.2
Let p, q be integers such that 2 $\leq$ p, q $\leq$ n, and let $D_{p, q}$ denote the matrix obtained from $I_{n}$, the identity matrix of order n, by replacing each of the first p columns by an all 1's vector and by replacing each of the first two rows and each of the last q-2 rows by an all 1's vector. In this paper the permanent minimization problem over the face, determined by the matrix $D_{p, q}$, of the polytope of all n $\times$ n doubly stochastic matrices is treated.d.