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OMICS approaches in cardiovascular diseases: a mini review
Sohag, Md. Mehadi Hasan,Raqib, Saleh Muhammed,Akhmad, Syaefudin Ali Korea Genome Organization 2021 Genomics & informatics Vol.19 No.2
Ranked in the topmost position among the deadliest diseases in the world, cardiovascular diseases (CVDs) are a global burden with alterations in heart and blood vessels. Early diagnostics and prognostics could be the best possible solution in CVD management. OMICS (genomics, proteomics, transcriptomics, and metabolomics) approaches could be able to tackle the challenges against CVDs. Genome-wide association studies along with next-generation sequencing with various computational biology tools could lead a new sight in early detection and possible therapeutics of CVDs. Human cardiac proteins are also characterized by mass spectrophotometry which could open the scope of proteomics approaches in CVD. Besides this, regulation of gene expression by transcriptomics approaches exhibits a new insight while metabolomics is the endpoint on the downstream of multi-omics approaches to confront CVDs from the early onset. Although a lot of challenges needed to overcome in CVD management, OMICS approaches are certainly a new prospect.
Hossain Amzad,Hassan Zahid,Sohag Mehadi Hasan,Khan Mursalin 한국작물학회 2023 Journal of crop science and biotechnology Vol.26 No.4
The exploration of knowledge for crop improvement has been a continuous practice to address the food insecurity of the growing human population, and the necessity of the new knowledge is crucial due to decreasing arable land and climate change. The proper use of technology and knowledgebase has the potential to narrow down poverty in the world, more specifcally in developing countries. This review aimed to assess the role of the endophytic and rhizospheric bacteria as a potential crop improvement tool in climate-smart agriculture. Endophytic and rhizospheric were found to be efcient alternatives to the chemical-based solution to develop crops. Endophytic and rhizospheric bacteria have improved many agronomic traits such as yield, quality, disease resistance, and stress tolerance. Besides, we discussed the recent development of the feld-level application of endophytic and rhizospheric bacteria. These bacteria have potential since they are efcient in developing crops signifcantly without afecting the environment in a deleterious way. In terms of biodiversity, natural resources such as endophytic and rhizospheric bacterial application to crops are unlikely to afect the non-target species. Hence, endophytic and rhizospheric bacteria application in crop improvement is applicable for agricultural development, thereby ensuring food sustainability without afecting the environment, eventually leading us to climatesmart agriculture. This review aims to recapitulate the current knowledge and prospects of endophytic and rhizospheric bacteria to achieve the goal of climate-smart agriculture