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        Preparation of Aromatic ${\beta}-Selenolactams$ and Their Bioactivities as Agricultural Chemicals

        Ishihara, Hideharu,Kato, Shinzi,Kimura, Mitsutoshi 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.8

        The purpose of this study was to investigate the possibility of aromatic ${\beta}-selenolactams$ being used in agricultural chemicals. A series of ${\beta}-selenolactams$ with aromatic substituents at the 1-, 2- and 3-positions were synthesized and their bioactivities were evaluated. Acarianicidal and insecticidal activity against common destructive insects, antibacterial activity against seven common plant pathogens, and plant growth activity of typical food crops were investigated. We found that introduction of 4-chloro and 4-methyl groups on 2- or 3-phenyl groups of the ${\beta}-selenolactam$ ring brought about acarianicidal activity against adults and eggs of Plutella xylostella. However, except for moderate to weak effect on fatality of Culex pipiens molestus Forskal, insecticidal activity against two other kinds of insects, antibacterial activity against plant pathogens, and activity on plant growth regulation were not detected among the ${\beta}-selenolactam$ derivatives.

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        Preparation of Aromatic β-Selenolactams and Their Bioactivities as Agricultural Chemicals

        Mitsutoshi Kimura,Hideharu Ishihara,Shinzi Kato 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.8

        The purpose of this study was to investigate the possibility of aromatic β-selenolactams being used in agricultural chemicals. A series of β-selenolactams with aromatic substituents at the 1-, 2- and 3-positions were synthesized and their bioactivities were evaluated. Acarianicidal and insecticidal activity against common destructive insects, antibacterial activity against seven common plant pathogens, and plant growth activity of typical food crops were investigated. We found that introduction of 4-chloro and 4-methyl groups on 2- or 3-phenyl groups of the β-selenolactam ring brought about acarianicidal activity against adults and eggs of Plutella xylostella. However, except for moderate to weak effect on fatality of Culex pipiens molestus Forskal, insecticidal activity against two other kinds of insects, antibacterial activity against plant pathogens, and activity on plant growth regulation were not detected among the β-selenolactam derivatives.

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