Effects site concentrations of propofol using target-controlled infusion in dental treatment under deep sedation among different intellectual disability types

Keyling, S,Salmeron, Salinas,Kim, Hyun Jeong,Seo, Kwang-Suk The Korean Dental Society of Anesthsiology 2019 Journal of Dental Anesthesia and Pain Medicine Vol.19 No.4

Background: We aimed to assess the dose needed to achieve the propofol effect-site concentration using target-controlled infusion in intellectually disabled patients and to detail the most effective method for achieving a safe level of consciousness without hemodynamic changes as well as detail any resulting adverse effects. Methods: We performed a retrospective review of sedation service records of 138 intellectually disabled patients (51, mental retardation; 36, autism; 30, brain lesion, 12 genetic diseases, 9 dementia) aged over 15 years and weighing over 30 kg. These patients had received propofol via target-controlled infusion in the special care dental clinic of Seoul National University Dental Hospital from May 2008 to September 2018 for restorative treatment (112), minor surgery (13), prosthodontics (7), periodontics treatment (5), and implant (1). Results: For all groups, the duration of dental treatments was $43{\pm}18$ minutes, total sedation time was $73{\pm}23$ minutes, and total BIS values was $57{\pm}12$. The propofol maintenance dosage values for each group were: mental retardation, $3{\pm}0.5(2-4){\mu}g/ml$; autism, $3.1{\pm}0.7(2-5){\mu}g/ml;$; brain lesion, $2.8{\pm}0.7(1.5-5){\mu}g/ml;$; genetic disease, $2.9{\pm}0.9(1-4){\mu}g/ml;$ and dementia $2.3{\pm}0.7(1-3.4){\mu}g/ml;$. Conclusions: The dementia group needed a lower dosage to reach a safe, effective propofol effect-site concentration than the other groups. Since there were no complications, deep sedation is a great alternative to general anesthesia for dental treatment of intellectually disabled patients.

Instantaneous Compensation in Three-Phase Four-Wire Systems: Line Power Loss Analysis

J.C. Montano,P. Salmeron,J. Prieto,H. Kim 전력전자학회 2004 ICPE(ISPE)논문집 Vol.- No.-

This paper discusses on the supply-line cable losses of shunt type active power filters (APF) in three-phase four-wire systems according to instantaneous compensation methods whether or not compensating the neutral current. According to instantaneous power compensation theory, the instantaneous-reactive current can be reduced without altering the instantaneous active power. Two compensation approaches are considered in this paper: 1) for eliminating the total instantaneous-reactive current where the neutral current can still flow; 2) for eliminating the modified instantaneous-reactive current where the neutral current is compensated at zero. It demonstrates that, in common situations of medium and low relative-values of the zerosequence voltage, the total cable losses (line and neutral) obtained with the second approach are lower than those obtained with the first approach. Simulation results confirm the theoretical analysis and show the compensator performance.

Fundamental Aspects of Energy Dissipation in Friction

Park, Jeong Young,Salmeron, Miquel American Chemical Society 2014 Chemical reviews Vol.114 No.1

<P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/chreay/2014/chreay.2014.114.issue-1/cr200431y/production/images/medium/cr-2011-00431y_0031.gif'></P>

Photochemical Hydrogen Production from a Water-Methanol Mixture with Iron Oxide Suspensions

Kim, I.K.,Salmeron, M.,Hendewerk, M.,Somorjai, G.A. 圓光大學校 基礎自然科學硏究所 1986 基礎科學硏究誌 Vol.5 No.2

Photochemical hydrogen production has been detected from small particles of doped iron oxide suspended in a methanol-water(1:1) mixture. The systems studied consisted of a pure n-type semiconductor, Fe_(2-x)Nb_XO_3 (x=0.02); a pure p-type semiconductor, La_(1-X)Sr_XFeO_3 (x=0.25), and Mg-doped α-Fe_2O_3. The efficiency of the reaction increased substantially when the powders were loaded with Pt. Of the systems investigated Mg-doped α-Fe_2O_3 showed the highest efficiency. In the case of Mg-doped α-Fe_2O-3 the existence of spinel phase inclusions in the α-Fe_2O_3 corundum structure remarkably enhances the photocatalytic reactivity, which may be a result of a cathodic shift of the conduction band edge of the corundum structure and also an increase in the conductivity of the material material. Hydrogen production from these Mg-doped iron oxides is photocatalytic and occurs mainly as a result of bandgap irradiation, but also occurs with sub-bandgap illumination. There is a linearly increasing dependence of the H_2 production with increasing light intensity.

Superlubric Sliding of Graphene Nanoflakes on Graphene

Feng, Xiaofeng,Kwon, Sangku,Park, Jeong Young,Salmeron, Miquel American Chemical Society 2013 ACS NANO Vol.7 No.2

<P>The lubricating properties of graphite and graphene have been intensely studied by sliding a frictional force microscope tip against them to understand the origin of the observed low friction. In contrast, the relative motion of free graphene layers remains poorly understood. Here we report a study of the sliding behavior of graphene nanoflakes (GNFs) on a graphene surface. Using scanning tunneling microscopy, we found that the GNFs show facile translational and rotational motions between commensurate initial and final states at temperatures as low as 5 K. The motion is initiated by a tip-induced transition of the flakes from a commensurate to an incommensurate registry with the underlying graphene layer (the superlubric state), followed by rapid sliding until another commensurate position is reached. Counterintuitively, the average sliding distance of the flakes is larger at 5 K than at 77 K, indicating that thermal fluctuations are likely to trigger their transitions from superlubric back to commensurate ground states.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancac3/2013/ancac3.2013.7.issue-2/nn305722d/production/images/medium/nn-2012-05722d_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nn305722d'>ACS Electronic Supporting Info</A></P>

Worldwide comparison of ovarian cancer survival: Histological group and stage at diagnosis (CONCORD-2)

the CONCORD Working Group,Matz, M.,Coleman, M.P.,Carreira, H.,Salmeron, D.,Chirlaque, M.D.,Allemani, C. Academic Press 2017 Gynecologic oncology Vol.144 No.2

Objective: Ovarian cancer comprises several histological groups with widely differing levels of survival. We aimed to explore international variation in survival for each group to help interpret international differences in survival from all ovarian cancers combined. We also examined differences in stage-specific survival. Methods: The CONCORD programme is the largest population-based study of global trends in cancer survival, including data from 60 countries for 695,932 women (aged 15-99years) diagnosed with ovarian cancer during 1995-2009. We defined six histological groups: type I epithelial, type II epithelial, germ cell, sex cord-stromal, other specific non-epithelial and non-specific morphology, and estimated age-standardised 5-year net survival for each country by histological group. We also analysed data from 67 cancer registries for 233,659 women diagnosed from 2001 to 2009, for whom information on stage at diagnosis was available. We estimated age-standardised 5-year net survival by stage at diagnosis (localised or advanced). Results: Survival from type I epithelial ovarian tumours for women diagnosed during 2005-09 ranged from 40 to 70%. Survival from type II epithelial tumours was much lower (20-45%). Survival from germ cell tumours was higher than that of type II epithelial tumours, but also varied widely between countries. Survival for sex-cord stromal tumours was higher than for the five other groups. Survival from localised tumours was much higher than for advanced disease (80% vs. 30%). Conclusions: There is wide variation in survival between histological groups, and stage at diagnosis remains an important factor in ovarian cancer survival. International comparisons of ovarian cancer survival should incorporate histology.

Photoassisted Catalytic Dissociation of H_2O to Produce Hydrogen on Partially Reduced α-Fe_2O_3

Khader, M. M.,Vurens, G. H.,Kim, I. K.,Salmeron, M.,Somorjai, G. A. 圓光大學校 基礎自然科學硏究所 1988 基礎科學硏究誌 Vol.7 No.3

The photodissociation of H_2O on partially reduced Fe_2O_3 powders and pellets is shown to be a catalytic process if the semiconductor is illuminated by visible light of energy greater than 2.2eV. Activation of the Fe_2O_3 catalysts involved reduction in a mixture of H_2O followed by oxidation. Up to 380 μmol of H_2 were produced with 190 μmol of Fe_2O_3 powder. The rate was 40 μmol h^-1 g^-1 for the first 200h and started to decay thereafter. O_2 was also produced as shown by using H_2^18O in amounts of up to 40 ± 15% of the amount of H_2 detected in the same experiment. In photoelectroehemical esperiments with use of a three compartment cell the active pellets produced photocurrents of approximately 4 μA cm^-2 mW^-1 at +0.5 V bias (SCE. pH 13). Simultancously, H_2 was produced at a rate of 0.06 μmol h^-1 mW^-1. A lower limit to the conversion efficiency of approximately 10^-3 H_2 molecules per photon is obtained.

Isotope- and Thickness-Dependent Friction of Water Layers Intercalated Between Graphene and Mica

Lee, Hyunsoo,Ko, Jae-Hyeon,Song, Hee Chan,Salmeron, Miquel,Kim, Yong-Hyun,Park, Jeong Young Springer-Verlag 2018 Tribology letters Vol.66 No.1

Internal and External Atomic Steps in Graphite Exhibit Dramatically Different Physical and Chemical Properties

Lee, Hyunsoo,Lee, Han-Bo-Ram,Kwon, Sangku,Salmeron, Miquel,Park, Jeong Young American Chemical Society 2015 ACS NANO Vol.9 No.4

<P>We report on the physical and chemical properties of atomic steps on the surface of highly oriented pyrolytic graphite (HOPG) investigated using atomic force microscopy. Two types of step edges are identified: internal (formed during crystal growth) and external (formed by mechanical cleavage of bulk HOPG). The external steps exhibit higher friction than the internal steps due to the broken bonds of the exposed edge C atoms, while carbon atoms in the internal steps are not exposed. The reactivity of the atomic steps is manifested in a variety of ways, including the preferential attachment of Pt nanoparticles deposited on HOPG when using atomic layer deposition and KOH clusters formed during drop casting from aqueous solutions. These phenomena imply that only external atomic steps can be used for selective electrodeposition for nanoscale electronic devices.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancac3/2015/ancac3.2015.9.issue-4/nn506755p/production/images/medium/nn-2014-06755p_0007.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nn506755p'>ACS Electronic Supporting Info</A></P>

연구원 활동 : 발표논문요약 ; < 화학공학분야 >

(Amir Berman),(Dong June Ahn),(Anna Lio),(Miquel Salmeron),(Anke Reichert),(Deborah Charych) 고려대학교 공학기술연구소 1996 생산기술연구소보 Vol.3 No.-