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S. Nagini,K.V.P. Chandra Mohan,V. Bhuvaneswari,S.K. Abraham 한국식품영양과학회 2003 Journal of medicinal food Vol.6 No.3
This study was designed to investigate the protective role of pretreatment with graded doses of freshly pre-pared tomato paste against 7,12-dimethylbenz[a]anthracene (DMBA)-induced genetic damage and oxidative stress in maleSwiss mice. The incidence of bone marrow micronuclei and the extent of hepatic lipid peroxidation and the antioxidants glu-tathione, glutathione peroxidase, and glutathione S-transferase were monitored. Three different concentrations (0.5, 1, and 2g/kg body weight) of tomato paste were tested for their anticlastogenic effects against DMBA (35 mg/kg body weight). In-creased frequency of micronuclei and enhanced lipid peroxidation accompanied by compromised antioxidant defenses wereobserved in DMBA-treated animals. Pretreatment with all three doses of tomato paste significantly reduced the frequenciesof DMBA-induced micronuclei and oxidative stress. These findings demonstrate that administration of tomato paste protectsagainst the clastogenic effects of DMBA by decreasing lipid peroxidation and enhancing the antioxidant status.
Highly selective CO<sub>2</sub> capture by S-doped microporous carbon materials
Seema, H.,Kemp, K.C.,Le, N.H.,Park, S.W.,Chandra, V.,Lee, J.W.,Kim, K.S. Pergamon Press ; Elsevier Science Ltd 2014 Carbon Vol.66 No.-
S-doped microporous carbon materials were synthesized by the chemical activation of a reduced-graphene-oxide/poly-thiophene material. The material displayed a large CO<SUB>2</SUB> adsorption capacity of 4.5mmolg<SUP>-1</SUP> at 298K and 1atm, as well as an impressive CO<SUB>2</SUB> adsorption selectivity over N<SUB>2</SUB>, CH<SUB>4</SUB> and H<SUB>2</SUB>. The material was shown to exhibit a stable recycling adsorption capacity of 4.0mmolg<SUP>-1</SUP>. The synthesized material showed a maximum specific surface area of 1567m<SUP>2</SUP>g<SUP>-1</SUP> and an optimal CO<SUB>2</SUB> adsorption pore size of 0.6nm. The microporosity, surface area and oxidized S content of the material were found to be the determining factors for CO<SUB>2</SUB> adsorption. These properties show that the as synthesized S-doped microporous carbon material can be more effective than similarly prepared N-doped microporous carbons in CO<SUB>2</SUB> capture.
S. Nagini,K.V.P. Chandra Mohan,R. Subapriya,Y. Hara 한국식품영양과학회 2006 Journal of medicinal food Vol.9 No.3
We evaluated the comparative chemopreventive efficacy of green tea polyphenols (polyphenon-E) and blacktea polyphenols (polyphenon-B) on 7,12-dimethylbenz[a]anthracene (DMBA)-induced hamster buccal pouch (HBP) carcino-genesis. Lipid peroxidation, reduced and oxidized glutathione (GSH and GSSG, respectively), and the GSH-dependent en-zymes glutathione peroxidase and glutathione S-transferase in the erythrocytes were used as biomarkers of chemoprevention.Enhanced lipid peroxidation in erythrocytes of DMBA-treated animals was accompanied by a significant decrease in the an-tioxidant status. Dietary administration of polyphenon-E and -B to DMBA-treated animals significantly decreased the extentof lipid peroxidation and enhanced the levels of GSH, GSH/GSSG ratio, and activities of GSH-dependent enzymes. Our studyprovides evidence that polyphenon-B is more effective in inhibiting HBP carcinogenesis than polyphenon-E by enhancing theantioxidant status, suggesting that polyphenon-B may have a major impact in the chemoprevention of oral cancer.
Multi-wavelength Study of Blazars Using Variability as a Tool
Kiran S. Baliyan,Navpreet Kaur,Sunil Chandra,Sameer,Shashikiran Ganesh 한국우주과학회 2016 Journal of Astronomy and Space Sciences Vol.33 No.3
Active galactic nuclei (AGN) are too compact to be resolved by any existing optical telescope facility, making it difficult to understand their structure and the emission processes responsible for their huge energy output. However, variability, one of their characteristic properties, provides a tool to probe the inner regions of AGN. Blazars are the best candidates for such a study, and hence a considerable amount of effort is being made to investigate variability in these sources across the electromagnetic spectrum. Here, using the Mt. Abu infrared observatory (MIRO) blazar monitoring program, we present intra-night, inter-night, and long term aspects of the variability in S5 0716+71, 3C66A, and OJ 287. These stars show significant variability on short (a few tens of mins, to a few hours, to a few days) to long term (months to years) timescales. Based on the light travel time argument, the shortest variability timescales (micro-variability) provide upper limits to the size of the emission region. While S5 0716 shows a very high duty cycle of variability (> 80 %), 3C66A shows a much lower intra day variability (IDV) duty cycle (< 20 %). All three show rapid variations within 2.5 to 3.5 hr, which, perhaps, are generated near the vicinity of black holes. Assuming this, estimates of the masses of the black holes are made at ~109, 8×108, and 2.7×109 M⨀ for S5 0716+71, 3C66A, and OJ 287, respectively. Multi-wavelength light-curves for the blazar PKS 1510-089 are discussed to infer the emission processes responsible for the recent flaring episodes in this source.
Age-related differences in the pathogenesis of chronic rhinosinusitis
Cho, S.H.,Hong, S.J.,Han, B.,Lee, S.H.,Suh, L.,Norton, J.,Lin, D.,Conley, D.B.,Chandra, R.,Kern, R.C.,Tan, B.K.,Kato, A.,Peters, A.,Grammer, L.C.,Schleimer, R.P. Mosby 2012 The Journal of allergy and clinical immunology Vol.129 No.3
Although chronic rhinosinusitis (CRS) significantly affects the quality of life of elderly people, the inflammatory mechanisms of chronic rhinosinusitis in the elderly have not been well studied. This study demonstrates that despite the higher severity of CRS observed in elderly patients, they had lower eosinophilic cationic protein compared to non-elderly CRS patients. In addition, S100A8/9 was significantly decreased in CRS with aging process, suggesting that epithelial barrier dysfunction may continue to play an important role in the pathogenesis of CRS while eosinophilic inflammation may subside with age.
Yesudasu Bammidi,Chandra S Angani,K Sambasiva Rao,M. B. Kishore,G. Krishna Podagatlapalli,S. Sreedhar 한국자기학회 2022 Journal of Magnetics Vol.27 No.2
Failures in the industrial components are unavoidable due to material degradation from various sources, thus continuous monitoring and timely inspection is mandatory for structural safety. In the present study, the recently developed Transient Eddy Current Oscillations (TECO) method is used to detect wall-thinning in a stainless-steel plate. Unlike the conventional Eddy Current Testing impedance plane data a new interpretation method has been implemented to identify a thickness variation using the S-domain parameters. Furthermore, time and frequency spectral features are analysed to get more insight into the results. The decay time and the resonant frequency are the basis for the discussion to assess the wall thickness.
Nagaraju, Goli,Cha, Sung Min,Sekhar, S. Chandra,Yu, Jae Su Wiley Blackwell (John Wiley Sons) 2017 Advanced energy materials Vol.7 No.4
<P>Highly flexible and conductive fabric (CF)-supported cauliflower-like nickel selenide nanostructures (Ni3Se2 NSs) are facilely synthesized by a singlestep chronoamperometry voltage-assisted electrochemical deposition (ECD) method and used as a positive electrode in supercapacitors (SCs). The CF substrate composed of multi-layered metallic films on the surface of polyester fibers enables to provide high electrical conductivity as a working electrode in ECD process. Owing to good electrical conductivity, high porosity and intertwined fibrous framework of CF, cauliflower-like Ni3Se2 NSs are densely integrated onto the entire surface of CF (Ni3Se2 NSs@CF) substrate with reliable adhesion by applying a chronoamperometry voltage of -1.0 V for 240 s. The electrochemical performance of the synthesized cauliflower-like Ni3Se2 NSs@CF electrode exhibits a maximum specific capacity (CSC) of 119.6 mA h g(-1) at a discharge current density of 2 A g(-1) in aqueous 1 m KOH electrolyte solution. Remarkably, the specific capacity of the same electrode is greatly enhanced by introducing a small quantity of redox-additive electrolyte into the aqueous KOH solution, indicating the CSC approximate to 251.82 mA h g(-1) at 2 A g(-1) with good capacity retention. Furthermore, the assembled textile-based asymmetric SCs achieve remarkable electrochemical performance such as higher energy and power densities, which are able to light up different colored lightemitting diodes.</P>
Chandra, I.,Kim, S.,Seto, T.,Otani, Y.,Takami, A.,Yoshino, A.,Irei, S.,Park, K.,Takamura, T.,Kaneyasu, N.,Hatakeyama, S. Pergamon Press ; Elsevier [distribution] 2016 Atmospheric environment Vol.141 No.-
<P>Field observations to investigate the correlation between New Particle Formation (NPF) and the long-range transport of air pollutants in the East Asia region were carried out on a rural Island of Japan in the East-China Sea (Fukue Island, 32.8 degrees N, 128.7 degrees E) over three periods (February 23 to March 7, 2013; November 7 to 20, 2013; and November 2 to 24, 2014). Frequent NPF events were identified (16 events in 50 days), typically in association with sudden increases in particle number concentrations and the successive growth of particles to mobility diameters of several tens of nanometers. The NPF events were classified into two types (A and B) according to the initially detected particle sizes (onset diameters). Type-A consisted of strong NPF events with onset diameters as small as 5 nm. Type-B consisted of NPF events whose onset (<10 nm) was not clearly identifiable. The correlations of SO2 concentrations, solar radiation, PM2.5 concentrations, and chemical composition were analyzed based on the types of NPF events. (C) 2016 Elsevier Ltd. All rights reserved.</P>